Gene Information

Name : Geob_0224 (Geob_0224)
Accession : YP_002535697.1
Strain : Geobacter daltonii FRC-32
Genome accession: NC_011979
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 270828 - 272480 bp
Length : 1653 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: sen:SACE_2694 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGATAAAAAATGGTTTTACTGAATGGCCGGAGGATTTCGCGCAAGCGTACCGGGATGCCGGTTACTGGCGAGACCAGAC
AATCGGCGAGGTGCTTGCAGAACGCTTCGCACGTTTCGCGGACAGAACCGCACTTATCGCTGAAGACGGGGCACACTATA
CCTATGCCGATCTGGACCGGCTTTCCACCCGCCTTGCCCTGCATTTCAAAAACCTGGGACTCCAACCATACGATCGGGTC
ATCCACCAGATCCCCAACGGCCCGGTAAGCGTCCTGACTTTTCTCGGGCTGCTCAAGGCGGGCGCCGTACCGGTGATGAC
ACTGCCCCCCCACCGGGAAGCGGAGATCGGCCACTTTGCCCGGCTTTCCGGGGCGCGTGGCTACGCCATAGCCAGCCAGG
TGCGTGAGTTCGACTTCCAGGCCCTGGCCGGCACGGTGCAGGAACAGAATCCGTCCCTGGAATTTGTACTGGTAACCGGC
GGCATGCCCGGTCCCGGCTATCAGTCCATCGATGCCATGCTGCTCGACCCCATCGAGGAACGGGCAGGCAGTACCAGCCT
GCCGCGACCCGATCCGGATTTTCCTGCCGTGCTGCTCCTGTCCGGTGGGACCACCGGCATTCCAAAGCTCATACCGAGAA
CCCACAACGACTATGCGTACAACTTTCTTCGCTGCGCCGAAGTATGCGGGCTTGACGGGGAGACCTCCGTACTCGTCGCC
GTGCCGCAGGCACACAATTTTGCCCTTGCCTGCCCGGGGCTGTTGGGCACCCTTGCCACCGGCGGCTGCGAACTGCTGTC
GGCAAACACCGCTACCGAACAGCTCATGAAGCTGATAGAGACGCACCGGTTGACCCATTTCATTGCCGTGCCGACGATGA
TTCTCGGCCTCCTCGACCATCCCGAGCGTGGCAAGTACGACCTCTCCTCCCTGCGGATGATCCTCACCGGCGGCTCGAAA
CTCAACCCGGAAGTGGCCCTGCGTCTGCGTCCGGAACTGGGATGTGACGTCCTGCAGGTCCTGGGCATGGCAGAAGGACC
TCTCTATTGGACACGTCTGGAAGACCCGGACGACGTGCGGCTGCATACCCAGGGCCGCCCCCAGTCCCCCGGCGACGAAT
TCCGTATCGTTGACCCGGAGAGCGGCAAAGAGGTGGCGCCGGGAGAAGTGGGAGAGCTCTGGTGCCGAGGACCCCACACG
ATCCGTGGCTATTATCGCGCCGACGAGCACAATACGCGGGCCTTCAGCTCCGACGGATTCTACAAGTCGGGAGACCTGGT
GCGGCTGCACGAAAGCGGCAACATCGTTGTCGAGGGACGGAACAAGGACTGCATCAACCGGGGAGGGGAAAAGATCAGCG
CCGAAGAGATCGAAAACCATCTCATCGCCCATGGGTCGGTGCTCAATTGTGCGGTCGTCGCCATGCCGGATGCCATTTTC
GGTGAAAAATGCTGTGCCTTTGTCGTCCCCGCTCCGGGCGCTTCCCTGACCCTGGAGGGTCTGTGCGACTTTCTCATCAA
GGAAAGAAAGATCGCCCGGTTCAAGCTTCCGGAGCGGTTGGAAACCTTGGACGCCCTTCCCCTGACAAACGTGGGCAAGA
TCAATAAAAAAGCCCTGCGTGAGATCATCGTGCAACTTCAGCAGGCTGCGTGA

Protein sequence : 
MIKNGFTEWPEDFAQAYRDAGYWRDQTIGEVLAERFARFADRTALIAEDGAHYTYADLDRLSTRLALHFKNLGLQPYDRV
IHQIPNGPVSVLTFLGLLKAGAVPVMTLPPHREAEIGHFARLSGARGYAIASQVREFDFQALAGTVQEQNPSLEFVLVTG
GMPGPGYQSIDAMLLDPIEERAGSTSLPRPDPDFPAVLLLSGGTTGIPKLIPRTHNDYAYNFLRCAEVCGLDGETSVLVA
VPQAHNFALACPGLLGTLATGGCELLSANTATEQLMKLIETHRLTHFIAVPTMILGLLDHPERGKYDLSSLRMILTGGSK
LNPEVALRLRPELGCDVLQVLGMAEGPLYWTRLEDPDDVRLHTQGRPQSPGDEFRIVDPESGKEVAPGEVGELWCRGPHT
IRGYYRADEHNTRAFSSDGFYKSGDLVRLHESGNIVVEGRNKDCINRGGEKISAEEIENHLIAHGSVLNCAVVAMPDAIF
GEKCCAFVVPAPGASLTLEGLCDFLIKERKIARFKLPERLETLDALPLTNVGKINKKALREIIVQLQQAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 43
ybtE CAA21394.1 - Virulence HPI Protein 2e-92 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-92 43
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-92 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-92 43
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-92 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 43
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-92 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Geob_0224 YP_002535697.1 AMP-dependent synthetase and ligase VFG0168 Protein 2e-95 46
Geob_0224 YP_002535697.1 AMP-dependent synthetase and ligase VFG1817 Protein 3e-92 44