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Name : leuS (CTN_0519) Accession : YP_002534061.1 Strain : Thermotoga neapolitana DSM 4359 Genome accession: NC_011978 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 520004 - 522523 bp Length : 2520 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : TTGATATTATTAGTAGAGAGCAGAGAAAAATCAGGAGGTGCGTCTATGAAGGAGTATAGGCCCCAGGAAATAGAAGAAAA ATGGCAGAAAGTTTGGGAAGAAAAGGGAGTGTTTCATACTCCACAGCGCTCTGAAAAACCGAAATACTACGCCCTTGTGA TGTTTCCCTATCCCTCCGGAACACTCCATGTGGGACATGTGAAAAACTACGTCATAGGAGACATCGTTGCCAGGTACAAG AGGATGAGAGGATACAACGTTCTCCATCCGTTTGGCTACGATGCCTTCGGATTGCCCGCAGAGAACGCGGCGATCGAGAA GGGAATACACCCTGAGGAGTGGACCAGGAAGAACATTTCCATCATCAGAAAACAGGTGAAGAGACTGGGTATAAGCTACG ACTGGAACAGAGAAATTGCAACTTGTGACGAGGAGTACTACAAATGGACTCAGTGGATATTCCTCCAGCTCTACAAGAAC GGACTTGCTTACAAGAAAAAGGCAGCCGTCAACTGGTGTCCAAAGTGCAAGACCGTCCTTGCCAACGAACAGGTGAAGGA CGGAAAATGTGAAAGGTGTGGAACGAGTGTGACCATAAAGCACCTTGAACAGTGGTTCTTCAAAATAACCGATTACGCGG AAAGACTGCTGAACGATCTGGAAAAGCTTACTGGCTGGCCCGAACACGTCAAGACGATGCAGAGAAACTGGATAGGAAAG AGCACGGGTGCAGAGATAGAGTTCCCCGTCGAGGGATCGGACACGAAAATAAGAGTCTTCACGACAAGACCCGACACGCT CTGGGGTGTCACCTTCATGGCGCTGGCACCGGAGTCACCACTCGTGGAGGAACTGGTGCCTGATGACAGAAAAGAAGATC TTCAGGCGTTTCTGGAACGTGTAAAACAGCAGGACAGATTCAAGAGAACGTCCGTGGAGGCGGAAAAAGAGGGATTCTTC CTGGGAAGGTATGCGGTGAATCCGGTGAACGGAGAGAGAGTACCCATCTACGTTGCAAACTACATACTCATGGAGTACGG AACGGGTGCCATCATGGGGGTGCCGGCTCACGATCAGAGGGACTTCGCCTTTGCCAGGAAATACGGAATACCCATAAAGG TGGTAATAAAACCTGTGGATGGAGAACTCGACCCGGATAAAATGGAAGAAGCATACGAAGGTGAAGGAATCATGGTCAAT TCCGGACCGTTCACAGGAACTCCAAGTAAGGAAGGTATTGAAAAGGTTATAAACTGGCTCGAGGAGAAGGGAATCGGTAA GCGGTCGGTTCAGTACAAGCTCAGAGACTGGCTCATATCCCGTCAGAGATACTGGGGGGCTCCCATTCCCATCATCTACT GCGAAAAGTGCGGAACCGTTCCGGTTCCGGAAGAAGATCTTCCGGTCAGACTTCCAAAAGACGTGGAGTTTCTCCCAACC GGACAGTCTCCCCTCTCTTTCCATGAAGGCTTCAAGAAGACAAAATGTCCGATCTGCGGCGGAGAGGCCCAGAGAGAAAC CGACACCATGGACACGTTCGTTGATTCCTCCTGGTACTTCCTCAGGTATGTGAATCCACATCTGGATGACAAGCCCTTCG AACCGGATGATGTGAACTACTGGCTCCCCGTGGACCAGTACATAGGTGGTGTGGAGCACGCCATTTTGCATCTGTTGTAC TCGAGGTTCATAACCAAAGTACTTCACGACCTTGGATATTTGAATTTCGACGAACCTTTCACCAATCTTTTCACTCAGGG AATGATATACAAAGATGGCGCCAAGATGTCGAAGTCGAAGGGGAACGTGGTATCTCCCGACGACATGATAGAAAAGTACG GAGCAGACACCCTGAGAATGTACATACTCTTCATGGCGCCTCCGGAAAAAGATGCCGAGTGGAGTGATGCAGGTATCGAA GGAGTGCACAGATTCATCAGAAGGCTCTGGAACACATTCTACACAATTTTGCCGCACGTGAAGGAAGAAACTGTCGAAGG GCTTTCGTTGACAACTCCCGTTGAAAAGGAACTCAGAAGAAAACTGCACAGCATCATCAAAAAGATAACAGAAGATATCG AAGGCGGATTCAAGTTCAACACGGCCATCAGTGGTCTCATGGAACTGATCAACCATCTGAATCAGTACCTGAGCGGTGTA CCAGAAGATCAGTGGAACAGAAAGCTTTTGAGGGAGATCGCAGAGAACCTCACACTGGTTCTATCACCGTTCGCACCACA TCTGGCGGAAGAGTTCTGGCACGAGCTGGGACAGGAGGGTCTTGTTGTTCAGCAATCGTGGCCATCCTACGATCCAAAAG CCCTTGAGGTCGAAGAAATGGAGATCGCCATTCAGATAAACGGAAAAGTGAGGGACAAGATCCTTGTTCCGGTGGACATC TCAGAGGAAGAACTGAAGAAGATGGTGATGGAGAGGGAAAGAGTCAAAGAATACATCGATGGAAAGACCGTGAAGAAGTT CATCTACGTGAAGGGAAGAATAGTAAATATCGTGATATGA Protein sequence : MILLVESREKSGGASMKEYRPQEIEEKWQKVWEEKGVFHTPQRSEKPKYYALVMFPYPSGTLHVGHVKNYVIGDIVARYK RMRGYNVLHPFGYDAFGLPAENAAIEKGIHPEEWTRKNISIIRKQVKRLGISYDWNREIATCDEEYYKWTQWIFLQLYKN GLAYKKKAAVNWCPKCKTVLANEQVKDGKCERCGTSVTIKHLEQWFFKITDYAERLLNDLEKLTGWPEHVKTMQRNWIGK STGAEIEFPVEGSDTKIRVFTTRPDTLWGVTFMALAPESPLVEELVPDDRKEDLQAFLERVKQQDRFKRTSVEAEKEGFF LGRYAVNPVNGERVPIYVANYILMEYGTGAIMGVPAHDQRDFAFARKYGIPIKVVIKPVDGELDPDKMEEAYEGEGIMVN SGPFTGTPSKEGIEKVINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCEKCGTVPVPEEDLPVRLPKDVEFLPT GQSPLSFHEGFKKTKCPICGGEAQRETDTMDTFVDSSWYFLRYVNPHLDDKPFEPDDVNYWLPVDQYIGGVEHAILHLLY SRFITKVLHDLGYLNFDEPFTNLFTQGMIYKDGAKMSKSKGNVVSPDDMIEKYGADTLRMYILFMAPPEKDAEWSDAGIE GVHRFIRRLWNTFYTILPHVKEETVEGLSLTTPVEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELINHLNQYLSGV PEDQWNRKLLREIAENLTLVLSPFAPHLAEEFWHELGQEGLVVQQSWPSYDPKALEVEEMEIAIQINGKVRDKILVPVDI SEEELKKMVMERERVKEYIDGKTVKKFIYVKGRIVNIVI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 4e-169 | 45 |
