Gene Information

Name : CTN_0488 (CTN_0488)
Accession : YP_002534030.1
Strain : Thermotoga neapolitana DSM 4359
Genome accession: NC_011978
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATPase subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 482581 - 485043 bp
Length : 2463 bp
Strand : -
Note : -

DNA sequence :
ATGTTTGATAAGTTCTCGGAAAAAACGGCTCAGATCTTTGTGACCGCCCAGGAAGAGGCAAAAGAACTCGGACATTCTTA
CGTGGGAACAGAACACCTTCTGCTCGCAATCCTGAAGGTAGATAAAGGTCCTGCTGTAGAAGTCCTTGAAGAGATGGGCG
CATCTTACTCGAAGGTAAGATCGGAGATCATCTCCATGGTTGGCATGGGGATGAGAGGTTTTGTCCCCTCACCTCAGATG
ACCCCCAGAGCCAAGAGGGTAACTGAGCTCGCCTATGAAGAGGCAAAGATCCTTGGAAGTGACAAGATAAATCCCGAGCA
CATTCTCCTTGGCATCCTCAGAGAAGGTGAAGGGATAGCGATCCACATACTGAGAAAACTGGGAGTGGATCTCAACGCTT
TGAGAAGGGAGATCATAGACCTGTACTCCTACTCTTCGAATAAAGGTTTGGAATACGAAGAGGAAGAAGACTACACCTAC
AGGTCCGTGAAACAACTCGAGGGATTCGGTGTCAACCTCACGGAACTTGCCGCAAAGAAAGAGTTAGACCCGGTCATAGG
AAGAGAAGAGGAAATAGAGAGGGTCATGCAGGTTCTTGTGAGAAGGAAGAAGAACAATCCAGTTTTGATAGGAGATCCAG
GAGTTGGTAAAACCGCCATCGTCGAAGGGCTCGCTCAGAGGATAGTGGCGGGTGACGTTCCGGAGATTTTGAGAAACAAG
GTTATCTTCTCGCTGGACGTCGCCGCTCTGGTTGCCGGCACAAAGTACAGAGGAGAGTTTGAAAAGAGAATGAAGAAGTT
GCTTCAGATAGTGACGAAAGACAAAAACATCATACTCTTCATAGACGAAATACACACGATCGTTGGAGCAGGTTCAGCGG
AGGGTGCCATCGACGCTGCAAACATTCTGAAACCCGCTCTTGCTCGGGGAGAGATAAGCTGTATAGGTGCAACCACACCG
GATGAGTACAGAAAGTACATAGAGAAAGATGCGGCCCTGGAAAGAAGGTTTCAGAAGATATATGTGAAGGAACCAACCGA
AGAGGAAACACTCGAGATCTTGAAAGGTCTGAAGAAGAAATACGAATCACACCACAGGGTGATATACACGGACAAAGCAT
TGGAGGCAGCAGTTTACCTGTCCAAAAGGTACATAACCGATCATTTCCTCCCGGATAAGGCGATCGATGTGATCGATGAA
GCGGGAGCCCGGGCAAGGCTCAAGGTCTTCATCATTCCTCCTGAGTTGAAATCAATCAAAAACGAACTGGAAAAGATAAG
AACCGACAAGGAACTTGCCGTTTTGAATCAGGATTACGAAAAGGCAGCAAAGTTGAAAGAGAAAGAAATGGAGCTTGAGA
CAGAGTACAGAAGAAAATATGCCGAGTGGAGAAGAAAGGCGGAAACGGCCGTTGTGAAAGTGGATGTCGATGATATAGCA
GAGGTTGTGTCCTCCTGGACAGGAGTGCCTCTCAAGAAGATCGAAGAAACGGAAGTGGAGAAACTCCTCAATCTCGAAGA
AGCGCTCCACCAGAGGATCGTCGCCCAGGACGAGGCAATAAAGGCTGTTGCGAGGGCTATAAGGAGAGCAAGAAGTGGCT
TGAAAGATCCAAGAAGACCGATTGGTGTCTTCCTCTTCCTTGGACCGACGGGAGTTGGAAAAACAGAACTTGCAAAGGCT
CTCGCAGAGTATCTGTTTGGTGATGAAAGAGCGCTCATAAGATTCGACATGAGCGAGTACATGGAGAGATTCTCTGTCTC
CAGGCTCATCGGAGCACCTCCTGGGTACGTGGGTTACGAAGAAGGAGGAACGCTCACAGAAAAAGTGAGAAGAAGGCCGT
TCTCCGTCATCCTGTTCGACGAAATAGAAAAGGCTCATCCAGATGTTTTCAACTTGCTTCTTCAGATCATGGATGATGGA
AGGCTCACCGACTCCCAGGGTCGCGAGGTCGATTTCAGAAACACCATAATCATCATGACAAGCAACATCGGAAGTTCCTA
CATCAACAAGTCCAAGAGGACCCTTGGATTCGTCGGTGACGATGACGAAGAGAAAGAATTCGATAAAATAAAGGAACTCG
TGCTCGATGAGGTGAAGAGGACATTCAGACCAGAGTTCCTGAACAGGATCGATGAGACCATCATCTTCCATCCACTCAGG
AAGGAACACATAGAACAGATCATCGATATACTCCTGAGGGATCTCAGAAAGAGATTGGCAGAGAAGAACATGAAACTTGT
TTTGACCAAGAGTGCAAAGGAATTTCTGGTTGAAAAAGGATTCGATCCAGTGTACGGTGCCAGACCTTTGAAGAGGGCGA
TTCAGAGATACGTTGAAGATCCTCTCTCCGAGGAGATACTGAAGAGCAAGTTCGAAGAAGGAGACACGATCGTCTGCAGG
GCTCACAAAGATGGTCTGAGATTCACGAAGAAGAAGGAAAAGAAAGAGAAGGTGGTCCAGTGA

Protein sequence :
MFDKFSEKTAQIFVTAQEEAKELGHSYVGTEHLLLAILKVDKGPAVEVLEEMGASYSKVRSEIISMVGMGMRGFVPSPQM
TPRAKRVTELAYEEAKILGSDKINPEHILLGILREGEGIAIHILRKLGVDLNALRREIIDLYSYSSNKGLEYEEEEDYTY
RSVKQLEGFGVNLTELAAKKELDPVIGREEEIERVMQVLVRRKKNNPVLIGDPGVGKTAIVEGLAQRIVAGDVPEILRNK
VIFSLDVAALVAGTKYRGEFEKRMKKLLQIVTKDKNIILFIDEIHTIVGAGSAEGAIDAANILKPALARGEISCIGATTP
DEYRKYIEKDAALERRFQKIYVKEPTEEETLEILKGLKKKYESHHRVIYTDKALEAAVYLSKRYITDHFLPDKAIDVIDE
AGARARLKVFIIPPELKSIKNELEKIRTDKELAVLNQDYEKAAKLKEKEMELETEYRRKYAEWRRKAETAVVKVDVDDIA
EVVSSWTGVPLKKIEETEVEKLLNLEEALHQRIVAQDEAIKAVARAIRRARSGLKDPRRPIGVFLFLGPTGVGKTELAKA
LAEYLFGDERALIRFDMSEYMERFSVSRLIGAPPGYVGYEEGGTLTEKVRRRPFSVILFDEIEKAHPDVFNLLLQIMDDG
RLTDSQGREVDFRNTIIIMTSNIGSSYINKSKRTLGFVGDDDEEKEFDKIKELVLDEVKRTFRPEFLNRIDETIIFHPLR
KEHIEQIIDILLRDLRKRLAEKNMKLVLTKSAKEFLVEKGFDPVYGARPLKRAIQRYVEDPLSEEILKSKFEEGDTIVCR
AHKDGLRFTKKKEKKEKVVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTN_0488 YP_002534030.1 ATP-dependent Clp protease, ATPase subunit VFG0079 Protein 0.0 56
CTN_0488 YP_002534030.1 ATP-dependent Clp protease, ATPase subunit VFG0080 Protein 8e-138 53