Gene Information

Name : CTN_0467 (CTN_0467)
Accession : YP_002534009.1
Strain : Thermotoga neapolitana DSM 4359
Genome accession: NC_011978
Putative virulence/resistance : Virulence
Product : Flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 461013 - 462308 bp
Length : 1296 bp
Strand : +
Note : -

DNA sequence :
TTGAAGAAAAGGCTGACTGAAGAGGACTTCAATCGCTTCAACGGAAGAGTGACACGCGTTGTCGGTCTCACCGTCGAATC
ACACGGACCCGATGCGTTTCTGGGAGAGATGTGCAAGATCTCCCTGCAGAACGGAAAGAACGCCCTGGCAGAGGTTGTTG
GTTTCAAAGAAGGAAATGTCGTTCTGATGCCCTATGAAGACGTTTCCGGACTGAAGATGGGCTGCGAGGTGATAAGAACA
AACAGAGTCCTGGAAATCGGTGTGGGCAGAAACATGATAGGCCGAATCTTCGACGGACTGGGCCGACCACTCGATGGAAG
ATCTTTCGTCCCGGAAGCGCGATACCCCCTGACAAACTCACCACCTCATCCCCTCAAAAGAAAAAGAATAAAAGATCCTC
TTTCAGTCGGTGTCAGAGCGATCGATGGCTTCATCACCATAGGGAAAGGGCAGAGAATCGGGATATTCGCAGGTAGTGGA
GTTGGAAAGAGCACGCTCCTTGGTATGATCGCACGGAACACAACGGCAGACGTGTGTGTGCTTGCACTGATTGGAGAGAG
GGGAAGAGAGGTCAGGGAATTCATAGAAAGAGACCTCGGTGAGGAGGGTTTGAAGCGCTCCATACTCGTGGTTTCCACTT
CCGATCAACCGGCCCTCGCCAGGGTGAAATCCCTTCTCACGGCCACCAGCATAGCGGAGTACTACAGGGATCTTGGCTAC
GACGTACTCTTGATGGTGGATTCACTCACCCGATGGGCCATGGCACAGAGAGAGGTCGGCCTTGCCATAGGAGAGCCCCC
GACCACCAGGGGCTATCCTCCCAGTGTGTTTGCTGGACTTCCAAAGATACTCGAAAGAGCGGGAAACTCAGACAGAGGGA
GTATAACAGCCGTCTACACGGTCCTCGTTGAGGCAGACGACTTCAACGAACCCATATCCGATACGGTTCGATCCATCGTG
GACGGCCACATCGTTCTTTCAAGGAGACTCGCAGAATCGAATCACTATCCGGCAATCGACGTGCTGGCGAGTGTGAGCAG
GTTGATGAACGACGTGGTTTCGGAAGAACACAAAGAGGCGGCGAACCGCCTCAGATCTTTGCTTGCCTCTTACGAGTCGG
CAAAAGACCTGATAGAGATAGGAGCCTATAAAAAAGGAACCAACCCTCTTGTCGACAAAGCGATTGAAATGCAAGAGGAT
ATCAACGCGTTCTTGAGACAGGGGATCTTCGAGAAATCTTCTTTCGAAGAAACCGTCCAGAGGCTTTTTGAACTTTCTTC
ACGTTCTCTTGACTAG

Protein sequence :
MKKRLTEEDFNRFNGRVTRVVGLTVESHGPDAFLGEMCKISLQNGKNALAEVVGFKEGNVVLMPYEDVSGLKMGCEVIRT
NRVLEIGVGRNMIGRIFDGLGRPLDGRSFVPEARYPLTNSPPHPLKRKRIKDPLSVGVRAIDGFITIGKGQRIGIFAGSG
VGKSTLLGMIARNTTADVCVLALIGERGREVREFIERDLGEEGLKRSILVVSTSDQPALARVKSLLTATSIAEYYRDLGY
DVLLMVDSLTRWAMAQREVGLAIGEPPTTRGYPPSVFAGLPKILERAGNSDRGSITAVYTVLVEADDFNEPISDTVRSIV
DGHIVLSRRLAESNHYPAIDVLASVSRLMNDVVSEEHKEAANRLRSLLASYESAKDLIEIGAYKKGTNPLVDKAIEMQED
INAFLRQGIFEKSSFEETVQRLFELSSRSLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-103 53
escN YP_003236088.1 translocator EscN Virulence LEE Protein 6e-90 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-90 51
escN AAK26715.1 EscN Virulence LEE Protein 1e-89 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-89 50
escN AAL57542.1 EscN Virulence LEE Protein 1e-89 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-89 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-89 50
unnamed AAL06369.1 EscN Virulence LEE Protein 8e-88 50
escN AAC31513.1 L0034 Virulence LEE Protein 3e-89 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-89 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-89 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-89 50
escN AAC38383.1 EscN Virulence LEE Protein 2e-89 50
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-89 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-86 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-86 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-98 49
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-98 49
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-98 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-89 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-89 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-89 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-88 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-88 49
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-96 49
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-96 49
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-98 49
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 6e-98 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-94 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-94 48
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-78 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-81 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-81 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-86 47
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-79 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 5e-79 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 5e-79 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-81 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-87 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-81 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-81 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 9e-82 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-66 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-66 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-66 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-66 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 5e-65 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG0192 Protein 1e-105 55
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG0390 Protein 2e-101 54
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG0048 Protein 2e-99 53
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG2144 Protein 2e-101 52
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG1254 Protein 2e-95 51
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG2331 Protein 4e-92 50
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG0730 Protein 1e-89 50
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG0812 Protein 2e-89 50
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG0515 Protein 1e-89 49
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG2499 Protein 1e-88 49
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG2459 Protein 4e-76 42
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG0555 Protein 5e-67 42
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG1778 Protein 5e-73 42
CTN_0467 YP_002534009.1 Flagellum-specific ATP synthase VFG1008 Protein 3e-66 41