Gene Information

Name : CTN_1212 (CTN_1212)
Accession : YP_002534754.1
Strain : Thermotoga neapolitana DSM 4359
Genome accession: NC_011978
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 1174381 - 1175658 bp
Length : 1278 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATAGACATAAAACTCATCAGGCAGGATCCCGATTTTGTGAAAGATGCCCTGAAAAAACGTGGTGAAGACACAGATAT
CATAGATGAGATACTGAAGATCGACAGCGAGTGGCGTTCTGTGACCACAGAACTCAACGAACTGAGGGCAAAAAGGAACG
ACATTTCCAAGAATGTGGCCAAGTTGAAGAAGGAAGGAAAGTCCTCCGAAGCGAACGCGCTGATCGAGGAAGGAAAAAGA
ATCGGTGAGGAAATAAAGTCACTCGAGGAGAAAGAAAAAGAACTTCAGTCAAAGCTAAGAGATCTTCTCCTCAGAGTGCC
GAACATTCCACATGAATCCGTTCCCGTTGGTTCCGATGAGTCTCAAAACGTTGAAGTGAGAAGGTGGGGCGAACCGAGGA
AATTCGACTTTGCTCCCCTGGCACACTGGGACCTCGGACCTGCCTGGGGACTCATGGACTTCGACAGGGCCTCCAAACTC
AGCGGCTCCAGGTTCACGGTGATGTACGGGAAACTTGCAAGACTGGAGAGGGCCCTCATAAACTTCATGCTCGACGTTCA
TACAAGAGAACACGGTTACACGGAGGTGTGGGTTCCACATCTTGTGAAAAGAGAAACGATCACGATCACAGGGCAGCTTC
CAAAGTTCGAAGAAGAGCTTTACCTGACAGAAAAAGACGACCTGTTTCTTATACCAACAGCAGAAGTTCCTCTGGTAGCC
CTCCACAGTGGAGAGATCCTTGAAGAAAAAGACCTTCCAAAGAAATACGTTGCCTACACTCCATGTTACAGAAGAGAAGC
CGGCAGTTACGGAAAAGATGTACGTGGAATGATCAGGCAGCACCAGTTCGACAAGGTGGAGCTCGTCTGGATAACCACAC
CGGAGAGATCCTTCGACGATCTGGAACAACTGGTAAGAGATGCCGAAACCATCCTTCAAAGGCTGGGGCTTCCCTACAGG
GTCGTCTCTCTCTGCACGGGAGATCTTGGATTCGCTTCCGCCAAAACGTATGACATAGAGGTGTGGCTTCCGTCCTACAA
CGCATACAAGGAGATCTCATCCTGCAGTAACGTGACGGACTTTCAGGCAAGAAGGGGTAACATGAGGTACAGAAGAAGGT
CAGACGGCAAACTCACACTCGTTCATACCCTTAACGGCTCAGGTATCGCGGTGGGAAGAACGCTGGTCGCGATTCTGGAG
AATTACCAGCAGCCAGATGGAAGCGTGAAGGTTCCAGAGGCACTAGTTCCTTACACGGGATTTGAGGTGATACCGTAG

Protein sequence :
MIDIKLIRQDPDFVKDALKKRGEDTDIIDEILKIDSEWRSVTTELNELRAKRNDISKNVAKLKKEGKSSEANALIEEGKR
IGEEIKSLEEKEKELQSKLRDLLLRVPNIPHESVPVGSDESQNVEVRRWGEPRKFDFAPLAHWDLGPAWGLMDFDRASKL
SGSRFTVMYGKLARLERALINFMLDVHTREHGYTEVWVPHLVKRETITITGQLPKFEEELYLTEKDDLFLIPTAEVPLVA
LHSGEILEEKDLPKKYVAYTPCYRREAGSYGKDVRGMIRQHQFDKVELVWITTPERSFDDLEQLVRDAETILQRLGLPYR
VVSLCTGDLGFASAKTYDIEVWLPSYNAYKEISSCSNVTDFQARRGNMRYRRRSDGKLTLVHTLNGSGIAVGRTLVAILE
NYQQPDGSVKVPEALVPYTGFEVIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-98 52