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Name : CTN_1161 (CTN_1161) Accession : YP_002534703.1 Strain : Thermotoga neapolitana DSM 4359 Genome accession: NC_011978 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 1126759 - 1129374 bp Length : 2616 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGTTGTTTTTTGACAAGAACAAGCGCATTTTGAAAAGGTACTCGAAGATCGTCGAAAAGATCAATCAGCTGGACCAGAG CATGAGAAAAAAGAGCAACGAAGAGATAGTTTCTCTGTCTTCTGAGTTAAAAGAGAGAGTAAACTCTCTCGAAGATGCAG ACAGGAACCTTGTGGAGGCCTTTGCCCTTGTGAGGGAAGCGGCTCGAAGGACGCTTGGTATGAGACCTTTCGATGTTCAG GTGATGGGAGGAATTGCCCTTCACGAAGGAAAAGTGGCAGAAATGAAGACGGGAGAGGGGAAGACGCTCGCCGCCACCAT GCCCGTGTACCTGAACGCCCTCATAGGAAAGGGTGTACACGTGGTCACCGTGAACGACTATCTTGCAAGAAGAGACGCCC TGTGGATGGGACCTGTGTACCTGCTTCTAGGGTTGAGAGTTGGGGTGATAAACTCCCTTGGGAAATCCTATGAAGTTGTC TGGAAGGACCCTTCACTGGTTGAGAAAGCGATAAAAGAAAACTGGAGCGTGTGGCCACAGGAGTTCGATGGGGAAATTCT AAAGGAAGAGCAGATGAACAAAGAGGCTCTGAACGCTTTTCAGGTGGAACTCAAAGAGATCTCAAGAAAAGAAGCCTACA TGTGTGATGTGACTTACGGTACAAACAACGAGTTCGGGTTCGACTACCTGAGAGACAACCTCGTTCTGGACTACAACGAC AAGGTCCAGAGAGGACACTTCTATGCCATAGTGGACGAGGCTGACAGCGTGTTGATAGACGAGGCAAGAACTCCCCTGAT CATCTCCGGACCATCTAAAGAGAGTCCTTCCACCTACAGAAGATTCGCTCAAATTGCAAAGAAGTTCGTCAAAGACAAAG ATTTCACGATCGATGAAAAGGCGAGAACGGTCATTTTGACCGAAGAGGGTGTGGCAAAGGCAGAAAAGATCATAGGTGTG GACAACCTCTATGAACCTGGGAACGTCTCCCTTCTGTACCACCTCATAAACGCCCTGAAAGCGCTACATCTCTTCAAAAA GGACGTCGATTACGTCGTCATGAACGGGGAAGTCATCATCGTCGATGAATTCACAGGAAGGCTCCTTCCCGGAAGACGCT ACAGTGGGGGATTACACCAGGCCATAGAGGCAAAAGAAGGGGTTCCGATAAAGGAAGAATCCATAACGTACGCCACGATC ACCTTCCAGAACTATTTCAGGATGTACGAAAAACTCGCGGGAATGACAGGAACCGCCAAGACGGAGGAAAACGAATTTGT TCAGGTTTACGGCATGGAGGTTGTGGTCATTCCAACGCACAGGCCCATGATAAGAAAGGACCACGATGATCTTGTTTTCA GAACACAGAAGGAAAAATACGAAAAGATCGTGGAGGAGATCGAAAAACGCTATAAAAAAGGTCAGCCAGTTCTTGTGGGT ACTACTTCCATAGAAAAGAGCGAACTCCTCAGTTCCATGCTGAAAAAGAAGGGAATACCTCACCAGGTGCTGAATGCAAA GCACCACGAAAAGGAAGCAGAGATCGTTGCCAAAGCCGGACAGAAGGGCATGGTGACCATAGCGACCAACATGGCCGGAA GGGGAACGGATATAAAACTCGGTCCCGGTGTGGCGGAGCTCGGTGGCCTCTGTGTCATTGGAACAGAAAGGCACGAAAGC AGAAGGATAGACAACCAGCTCAGGGGTCGAGCCGGAAGGCAGGGAGATCCTGGAGAATCAATATTCTTCCTCTCGCTGGA AGACGACCTTCTGAGGATCTTCGGTGGAGAACAGATAGGAAAGGTGATGAAAATACTCAAGATAGAAGAAGGTCAGCCCA TACAGCATCCCATGCTTTCAAAGCTCATAGAGAACATACAGAAGAAGGTGGAGGGAATAAACTTTTCCATAAGGAAATCC CTCATGGAGATGGACGAAGTCCTGGACAAACAGAGAAGCACCATATACTCTCTTCGAGATCAGATACTTCTGGAAAAAGA CTACGATGAGTACCTGAAACAGATCTTCGAAGACGTTATCGGAACAAGGGTAGAGGAATTTTGCTCCGGCAAAAACTGGG ATCTCGAAGGTCTGAAAAACTCTCTTTCGTTCCTTCCAAGAGATCTCTTCGAATTCGATGGAAGGCGTTTCGAATCGTCC GAAGAGCTCTACGAGTATCTTTTCAATAGAATGTGGGAGGAGTATCAGAAAAAGAGACAGGAAATAGGAGAAGAATACAG CAAAGTAATCAGGTTTTTAATGCTTCGAATCATCGACGAGCACTGGAGAAGATACCTTGAGGAAGTGGAACACGTCAGGG AAGCGGTTCAGTTGAGGGCGTATGGACAGAAAGATCCTATCGTCGAATTCAAAAAAGAAACGTACCTTATGTTCGATGAG ATGATGAGAAGGATCAACGACACGATAGCCAATTATGTCCTGAGAGTGGTCAAGGTGACGGAAAAGGATGAAAAAGAAGC GAAAGAGGAACTTGGTAAAATAAGACTTGTACACGAGGAATTCAACCTTGTGAACAGGGCCATGAGAAGGGCCATGGAGA AAGGGAAGAAAAAAGGTGGTTCACATGGACTTGGTAAAATAAGAGTGAAGAGGTGA Protein sequence : MLFFDKNKRILKRYSKIVEKINQLDQSMRKKSNEEIVSLSSELKERVNSLEDADRNLVEAFALVREAARRTLGMRPFDVQ VMGGIALHEGKVAEMKTGEGKTLAATMPVYLNALIGKGVHVVTVNDYLARRDALWMGPVYLLLGLRVGVINSLGKSYEVV WKDPSLVEKAIKENWSVWPQEFDGEILKEEQMNKEALNAFQVELKEISRKEAYMCDVTYGTNNEFGFDYLRDNLVLDYND KVQRGHFYAIVDEADSVLIDEARTPLIISGPSKESPSTYRRFAQIAKKFVKDKDFTIDEKARTVILTEEGVAKAEKIIGV DNLYEPGNVSLLYHLINALKALHLFKKDVDYVVMNGEVIIVDEFTGRLLPGRRYSGGLHQAIEAKEGVPIKEESITYATI TFQNYFRMYEKLAGMTGTAKTEENEFVQVYGMEVVVIPTHRPMIRKDHDDLVFRTQKEKYEKIVEEIEKRYKKGQPVLVG TTSIEKSELLSSMLKKKGIPHQVLNAKHHEKEAEIVAKAGQKGMVTIATNMAGRGTDIKLGPGVAELGGLCVIGTERHES RRIDNQLRGRAGRQGDPGESIFFLSLEDDLLRIFGGEQIGKVMKILKIEEGQPIQHPMLSKLIENIQKKVEGINFSIRKS LMEMDEVLDKQRSTIYSLRDQILLEKDYDEYLKQIFEDVIGTRVEEFCSGKNWDLEGLKNSLSFLPRDLFEFDGRRFESS EELYEYLFNRMWEEYQKKRQEIGEEYSKVIRFLMLRIIDEHWRRYLEEVEHVREAVQLRAYGQKDPIVEFKKETYLMFDE MMRRINDTIANYVLRVVKVTEKDEKEAKEELGKIRLVHEEFNLVNRAMRRAMEKGKKKGGSHGLGKIRVKR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 5e-110 | 41 |
