Gene Information

Name : clpC (BCQ_0095)
Accession : YP_002527902.1
Strain : Bacillus cereus Q1
Genome accession: NC_011969
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpc/mecb (ATP-dependent clp protease)
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 89509 - 91944 bp
Length : 2436 bp
Strand : +
Note : Code: O; COG: COG0542

DNA sequence :
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCGATTCGTATTGGGCATAA
CAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCGTTGATTGCTCTTG
GATTAAGCCCGGAGAAAGTTCAAAAAGAAGTAGAAGCGTTAATTGGACGCGGAACAGAAGCTTCTCAAACCGTACATTAT
ACACCGCGTGCTAAAAAGGTTATTGAGCTGTCTATGGATGAAGCTCGTAAATTAGGTCATTCTTACGTTGGAACAGAACA
TATTCTACTTGGTTTAATCCGCGAGGGTGAAGGGGTAGCAGCACGTGTTTTAAATAACTTAGGTGTTAGCTTAAATAAGG
CAAGACAACAAGTATTGCAACTTCTTGGAAGTAATGAAGCAAGTTCAGGTCATCAAGGTGGTTCTTCAACAAATGCAAAT
ACACCAACACTTGATAGCTTAGCACGTGATTTAACAGTTGTTGCACGTGAAAATCGTTTAGACCCTGTTATTGGACGTGG
TAAAGAAATTCAACGTGTAATTGAAGTTTTAAGCCGTAGAACGAAAAACAATCCTGTATTAATTGGGGAGCCTGGTGTAG
GTAAAACGGCAATTGCAGAAGGATTAGCACAACAAATCGTAAATAATGAAGTTCCTGAAACTTTAAGAGATAAGCGTGTT
ATGACACTAGATATGGGTACAGTGGTAGCCGGAACGAAATACCGTGGTGAATTTGAAGACCGTTTGAAGAAAGTAATGGA
TGAAATCCGCCAAGCAGGAAATATCATTCTATTTATTGATGAACTTCATACATTAATTGGTGCAGGTGGAGCAGAAGGTG
CTATTGACGCATCGAACATTTTAAAACCATCTTTAGCTCGTGGGGAATTACAATGTATTGGAGCGACAACGTTAGATGAA
TACCGCAAATATATTGAAAAAGACGCAGCTTTAGAGAGACGTTTCCAACCAATTCACGTTGATGAGCCAAGTTTAGATGA
ATCAACTCAAATTTTGAAAGGTTTACGCGATCGTTATGAGGCACATCACCGCGTATCTATTACAGATGATGCAATTGATG
CAGCTGTAAAGCTTTCAGATCGTTATATTACAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAGGTTCGCTTACGCTCTTATACAACACCACCAAATCTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTAGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAGTTTGAAAAAGCTGCTTCCTTACGTGATATGGAACAACGTTTACGTGAGAAGT
TAGAAGATACGAAGCGTCAATGGAAAGAGCAACAAGGAAAAGAAAACTCAGAAGTGACAGTAGAAGATATTGCAAATGTT
GTTTCTACGTGGACTCGTATCCCGGTTTCTAAGCTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCGATTCT
TCACGATCGTGTTATTGGTCAAGATGAAGCGGTAGTAGCTGTAGCGAAAGCTGTTCGTCGTGCTAGAGCAGGCTTGAAAG
ATCCGAAACGTCCGATTGGTTCATTTATTTTCTTAGGACCAACAGGTGTAGGTAAAACGGAGCTAGCAAGAGCGTTGGCA
GAATCTATGTTCGGTGATGAGGATGCAATGATTCGCATCGATATGTCTGAGTACATGGAGAAGCATTCTACTTCTCGTTT
AGTTGGATCTCCTCCAGGATATGTTGGATATGAAGAAGGTGGACAATTAACAGAAAAGGTTCGCCGTAAGCCATATTCAG
TTGTCTTATTAGATGAAGTAGAGAAAGCTCATCCTGATGTGTTTAACATTTTACTACAAGTATTAGAAGATGGTCGCTTA
ACAGATTCTAAAGGGCGTACAGTTGATTTCCGTAATACAATTGTTATTATGACATCTAACGTTGGTGCAGAAGCGTTAAA
ACGTAATAAACATCTTGGATTTAACGTACAAGATGAGAGCCGCGATTATTCAGATATGAAAGGTAAAGTAATGGATGAAC
TGAAAAAGGCATTCCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTGTTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACACTTATGGTAAATCAGTTAGTAAATCGCTTAAAAGAGCAAGAAATTGAATTGCATTTAACAGAAGG
AGCGATTTCGGCTATTGCTGATAAAGGGTTTGACCGAGAGTACGGTGCTCGTCCGCTTCGTAGAGCAATTCAGAAACATG
TAGAAGATAGACTATCGGAAGAACTTTTAAAAGGTGCTATTGAGAAAGGACAAAAAGTTATCTTTGATGTTGAAGGAGAA
TCATTTGTCATTCATAGTGCTGAAAAGGTAAAATAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLDESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_002527902.1 negative regulator of genetic competence clpc/mecb (ATP-dependent clp protease) VFG0079 Protein 0.0 77
clpC YP_002527902.1 negative regulator of genetic competence clpc/mecb (ATP-dependent clp protease) VFG0080 Protein 5e-148 52