Gene Information

Name : dhbE (BCQ_2296)
Accession : YP_002530013.1
Strain : Bacillus cereus Q1
Genome accession: NC_011969
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 2258746 - 2260362 bp
Length : 1617 bp
Strand : +
Note : Code: Q; COG: COG1021

DNA sequence : 
ATGCTAACAGGTTATACAAAATGGCCAAAAGAATTTGCTGATCGTTATCGAGAGGAAGGGTGTTGGCTTGGGGAAACATT
TGGCGGGATGTTAAGAGAGCGAGCTGAAAAATATGGCGATCAAATTGCAGTTGTAAGTGGTAATACGCATATTACGTATA
GTGAGTTTGATAAAAAAGTAGATCGATTAGCTTCAGGGCTACTGAATTTAGGAATAAAGCAAGAGGATCGAGTTGTAATC
CAGCTACCTAACGTTATTGAGTTTTTCGAAGTATGTTTTGCGCTATTTCGAATTGGGGCACTTCCTGTTTTTGCATTACC
TTCACATCGAAGCAGTGAAATTAGTTATTTTTGTGAGTTTGGTGAGGCGAGTGCTTACGTTATTTCAGATAAAGCTCTCG
GTTTTGATTATCGAAAACTAGCAAGAGAAGTGAAAGAGAAAGTGCCAACTTTACAACATGTAATTGTAGTGGGAGAAGAA
GAAGAATTTGTGAACATAAGTGATTTATATATAGATCCCGTTCCATTACCAGAAGTTCAGCCAAGTGATGTTGCGTTTCT
CCAATTATCAGGGGGGACAACAGGACTTTCTAAATTAATTCCTCGAACGCATGATGATTATATTTATAGTTTACGTGTTA
GCGCTGAAATTTGTAATTTAAGTGCAAAGAGTGTCTATATGGCCGTTCTTCCAGTAGCACATAATTACCCGATGAGCTCT
CCTGGAACATTTGGAACTTTCTATGCGGGTGGAAAAGTAGTGCTGGCAACTGGAGGTAGTCCAGATGAGGCATTTGCACT
TATTGAAAAAGAAAAAGTTACGATTACTGCTCTCGTACCGCCATTAGCAATGATATGGCTTGATGCTGCATCTTCACGTA
ATAACGATTTATCGAGTCTAGAAGTGATTCAAGTAGGTGGCGCGAAATTTAGTGCTGAAGTTGCAAAACGTATACGCCCT
ACATTTGGATGTACATTACAGCAAGTATTCGGTATGGCGGAAGGATTAGTGAACTATACAAGATTAGATGATCCTGAAGA
AATTATTATTCATACACAAGGTAGACCAATGTCTGCACTCGATGAAGTACGAGTTGTTGATGAAAATGACAACGATGTAA
AACCTGGCGAAGTAGGTAGTTTATTAACAAGAGGGCCATATACAATTCGTGGTTATTATAAAGCAGAAGAGCATAATGCA
CAATCGTTTACAAAGGATGGATTTTATCGCACAGGAGATCTTGTGAAAGTAAATGAACAAGGTTACATCATTGTAGAAGG
AAGAGATAAAGATCAAATTAATCGTGGTGGTGAGAAAGTTGCCGCGGAAGAAGTTGAAAATCATCTATTAGCACATGATG
CAGTACATGATGTAGCGATTGTATCTATGCCTGACGATTATTTAGGAGAACGTACTTGTGCATTTGTTATAGCTCGCGGA
CAAGCTCCGGCAGTAAGTGAATTAAAAAAATTTTTAAGAGAGCGTGGTATAGCAGCTTATAAGATTCCAGATCGAATTGA
ATTTATTGAATCATTCCCGCAAACAGGCGTTGGAAAGGTAAGCAAAAAAGAACTACGTAAAGTCATTGCTGAAAAACTTA
TTACAGTAAAACAATAA

Protein sequence : 
MLTGYTKWPKEFADRYREEGCWLGETFGGMLRERAEKYGDQIAVVSGNTHITYSEFDKKVDRLASGLLNLGIKQEDRVVI
QLPNVIEFFEVCFALFRIGALPVFALPSHRSSEISYFCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEE
EEFVNISDLYIDPVPLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSAKSVYMAVLPVAHNYPMSS
PGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSRNNDLSSLEVIQVGGAKFSAEVAKRIRP
TFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQGRPMSALDEVRVVDENDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNA
QSFTKDGFYRTGDLVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTCAFVIARG
QAPAVSELKKFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKELRKVIAEKLITVKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-120 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 6e-120 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-120 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-120 50
ybtE CAA21394.1 - Virulence HPI Protein 6e-120 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-120 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 4e-120 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-120 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 8e-120 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_002530013.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 3e-136 52
dhbE YP_002530013.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-112 47
dhbE YP_002530013.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 3e-111 44