Gene Information

Name : thyA (BCQ_2174)
Accession : YP_002529891.1
Strain : Bacillus cereus Q1
Genome accession: NC_011969
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 2150347 - 2151303 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACATGCTGAAAATGAATACTTAAATTTATGCCGCCATGTAATGGAGCATGGTACGAAGAAAGAAGATCGTACAGG
GACAGGCACTGTATCTGTATTTGGTTATCAAATGCGTTTTGATCTAAGTAAAGGTTTTCCTTTATTAACGACAAAGAGGG
TGCCATTTCGCCTTGTAGCAAGTGAATTGCTTTGGTTTATGAAAGGCGATACAAATATTCGTTATTTATTGCAGCATAAT
AACAACATTTGGAATGAATGGGCATTTAAGAGTTGGGTAGAAAGTGACGAGTATACGGGTCCTGACATGACTGATTTCGG
TCTTCGCTCACAACAAGATGAGGAATTTAAAGTTCAGTACGATGAGCAAATGGAATTGTTTAAAAAGAACGTTTTAGAAG
ATGATGATTTCTCAAATAAATATGGTTATTTAGGAGACGTATACGGTAAGCAGTGGCGTGCTTGGAAAACGACAGCTGGT
GAGACGCTTGATCAATTAAAAGATGTAATTGAAATGATAAAAAAAACGCCAGATTCACGTCGCCTAATTGTATCTGCTTG
GAATCCTGAAGATGTACCAAGTATGGCATTACCACCTTGTCATACGTTATTCCAATTTTATGTAGCAGATGGCAAACTTT
CTTGTCAGCTATATCAAAGAAGTGGTGATATATTCCTTGGAATTCCATTTAACATTGCAAGTTACTCGTTACTAACACAT
TTAATTGCACATGAATGCGGACTTGAAGTGGGAGAATTTGTTCATACAATTGGAGATGCCCACATTTATACGAATCATTT
TGAGCAAGTAGAAAAGCAATTGGCGCGTGAACCACGTCCGTTCCCAAAACTTACATTAAATCCAGGTGTGAAATCTGTGT
TTGATTTTGAAATGGAAGATTTAACGATTGAAGGATATGATCCACACCCAGCAATTAAAGCACCGGTTGCAGTGTAA

Protein sequence :
MKHAENEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHN
NNIWNEWAFKSWVESDEYTGPDMTDFGLRSQQDEEFKVQYDEQMELFKKNVLEDDDFSNKYGYLGDVYGKQWRAWKTTAG
ETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTH
LIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPGVKSVFDFEMEDLTIEGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-105 65