Gene Information

Name : guaA (RSKD131_1313)
Accession : YP_002525674.1
Strain :
Genome accession: NC_011963
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1345817 - 1347373 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAGCACGACCGTCTCCTCATCATCGATTTCGGGTCGCAGGTGACCCAGCTCATCGCGCGCCGCCTGCGCGAGCT
GAATGTCTACTGCGAGATCCATCCCTATCAGAACGTGACCGAAGCCTTCCTGAAGGGCTTCGCTCCGAAGGCCGTCATCT
TCTCCGGCGGCCCCTCCTCGGTCTTCGCCGAGGGCGCGCCGATGCCCCCCGCGGGCGTGTTCGACCTCGGCGTGCCGATC
CTCGGGATCTGCTACGGGCAGCAGGTGATGATGCACTGCCTCGGCGGCAAGGTCGAGCGCGGCCACGGCACCGCCGAATT
CGGCCGCGCCTTCGTGACCCCCACGGCGGAGCGTCTGGCGATCCTCGACGGCTGGTTCGAGGAAGGCCGCGAGCAGGTCT
GGATGAGCCACGGCGACCATGTCTCGCAGATCGCGCCGGGCTTTCAGGTGTTCGGCACTTCGCCCAACGCGCCCTTCGCC
ATCACCGGCGATCCCGCGCGCCATTTCTATGCGGTGCAGTTCCACCCTGAGGTGCACCACACGCCGAAGGGCGCGAAGCT
CTACGAGAATTTCGTGCGCCTCGCGGGCTTCAAGGGCGACTGGACGATGGGGGCCTACCGCGAGGAGGCGATCGCCAGGA
TCCGGGCCCAGGTGGGCGACCAGAAGGTGATCTGCGGCCTCTCGGGCGGCGTCGACAGTTCGGTCGCAGCGGTGCTGATC
CACGAGGCCATCGGCGATCAGCTGACCTGCGTATTCGTCGACCACGGCCTGCTGCGCCTCGGCGAGGCCGAGCAGGTGGT
CAAGATGTTCCGCGACCATTACAACATGCCGCTGATCCATGCCGACGAATCCGATCTCTTCCTCGGCGCGCTCGAGGGCG
TCTCGGACCCGGAAGTGAAGCGCAAGACCATCGGCCGGCTCTTCATCGACGTGTTCCAGAAGCACGCGGCCGACGTGGGC
GGCGCCACCTTCCTCGCGCAGGGCACGCTCTATCCCGACGTGATCGAGTCGGTGAGCTTCTCGGGCGGTCCCTCGGTCAC
GATCAAGTCGCACCACAATGTGGGCGGCCTGCCCGAGAAGATGGGCCTGAAGCTCGTCGAACCGCTGCGCGAACTCTTCA
AGGACGAGGTCCGCGCCCTCGGGCGCGAGCTCGGCCTGCCCGAGAGCTTCATCGGCCGCCACCCCTTCCCCGGCCCCGGC
CTCGCGATCCGCTGCCCCGGCGAGATCACCCGCGAGAAGCTCGAGATCCTGCGCCGGGCCGATGCGGTCTATATCGACCA
GATCCGCCGCCACGGGCTCTACGACGAGATCTGGCAGGCCTTCGTGGCGCTCCTGCCGGTGCGCACCGTGGGCGTGATGG
GCGACGGGCGAACCTACGACTATGCCTGCGCGCTCCGCGCCGTGACGAGCGTCGACGGCATGACCGCCGACTATTATCCC
TTCACCCACGACTTCCTCGGCGAGACGGCGACGCGGATCATCAACGAGGTGCAGGGCATCAACCGCGTGACCTACGACAT
CACCTCGAAGCCGCCGGGCACGATCGAGTGGGAATGA

Protein sequence :
MTQHDRLLIIDFGSQVTQLIARRLRELNVYCEIHPYQNVTEAFLKGFAPKAVIFSGGPSSVFAEGAPMPPAGVFDLGVPI
LGICYGQQVMMHCLGGKVERGHGTAEFGRAFVTPTAERLAILDGWFEEGREQVWMSHGDHVSQIAPGFQVFGTSPNAPFA
ITGDPARHFYAVQFHPEVHHTPKGAKLYENFVRLAGFKGDWTMGAYREEAIARIRAQVGDQKVICGLSGGVDSSVAAVLI
HEAIGDQLTCVFVDHGLLRLGEAEQVVKMFRDHYNMPLIHADESDLFLGALEGVSDPEVKRKTIGRLFIDVFQKHAADVG
GATFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPEKMGLKLVEPLRELFKDEVRALGRELGLPESFIGRHPFPGPG
LAIRCPGEITREKLEILRRADAVYIDQIRRHGLYDEIWQAFVALLPVRTVGVMGDGRTYDYACALRAVTSVDGMTADYYP
FTHDFLGETATRIINEVQGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-126 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-126 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-126 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-113 52