Gene Information

Name : lysS (trd_0874)
Accession : YP_002522097.1
Strain : Thermomicrobium roseum DSM 5159
Genome accession: NC_011959
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 853815 - 855404 bp
Length : 1590 bp
Strand : +
Note : identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499

DNA sequence :
ATGCCGCTCAACGATCAGCAGCGCGCACGGCTCGAAAAGCTCCGCGAACTACGCCAACAGGGTATCGACCCGTATCCGGC
TCGTTCGCATCGCCAATTGACTGCAGCGCAGGCGCACGCTGTCTTCACCGAGCGCGAGCCGCACCTCGGTGGCCAGCCCG
ATCCCGAACCAGTCACGCTGGCTGGCCGCGTCGTCTCCGTTCGCGACATGGGACGGACCGTCTTCAGTCATATCCGGGAC
GGGTCAGGAGCGATCCAACTCTTCTTGCGCCGCGAGTTCGTCGGTGATGACCAACTGGCATGGTTCAAGCGCTACGTCGA
CCTGAACGATTTCGTCGAAGCCGATGGGCATCTCTTCCGCACACGAACCGGTGAAGTTTCTCTCGAGGTGCACGCGCTCC
GACTGCTGAGCAAGGCGCTCAATCCGCCACCGGACAAGTGGCACGGGTTGACCGACGTCGAAACGCGCTACCGCCAACGC
TATGTCGACCTCATGGCCAACCCGGACACGCGACAAATCTTCGTGACACGGGCCCGCGTCATTCGCGCGATCCGTCAGTA
CCTGGACGAACGCGGCTTTCTCGAGGTCGAGACACCCACGCTCCAACCGATCTATGGCGGTGCTGCAGCCCGCCCCTTCA
CCACCTACTACCATGCTCTGGATCAGACCTTCTATTTGCGTATTTCCGACGAACTCTATCTCAAGCGGCTTCTCGTCGGT
GGCTACGAGCGCGTTTACGAGATTTGCAAGGACTTTCGCAATGAAGGGATCGATGCTCGGCATAACCCTGAATTCACCAT
GCTCGAGTTTTATGCAGCGTATGCCGATTACCACGATATCATGCAGATGTGCGAGGAATTGATCGTTTTCGCAGCACGCG
AGGCCCTCGGCACTTTGACCTTCCAGTGGGGAGACACGGTTATCGACTTGACACCGCCGTGGGCCCGAATGAGCTTGCGC
GAGGCACTACTTCGTTTCACCGGAATCGATTTTCTGGAAGTGACCGACCAGCCGACACTCTATGCGCGCGCCCGAGCTCT
CGGAGCCGACGTGGAGCCCACCACGGTCTGGCCTCGCATTCTCGACGAACTCCTCAAGACCTTCGTTCGGCCGCGTCTCG
TCCAACCGACGTTCATCTACGATTACCCTGTGGCTCTGTCACCGCTCGCTAAGCGCAAGCCGGAGGATCCACGCCTCGTC
GAGCGTTTCCAACTCTTCGTTGGGGGGCTGGAACTCGCGAACGCATATACCGAGTTGAACGATCCGCTCGATCAGTTGTA
CCGCTTCCTCGAGCAAGCACGCGACCGGGCGCAAGGAGACGAGGAAGCGATGCCGATCGACGAGGACTTCATCAACGCCT
TGATGTACGGTATGCCACCAACGGGCGGATTCGGTCTCGGCATCGACCGGCTGGTCATGCTCTTCACGAATCGGCCAACG
ATCCGCGAGGTCATCTTGTTCCCACAGCTTCGCACCAAACCTCAACCGCTGGGGCTCGCCGAAGACTTACAGCCGTACCT
CGAACTGGTTCCCGGGTTTCAAGAATCGGTGTCGACCGGCAGCGCGTCACCCGAAGGCGAAGCCGGCTGA

Protein sequence :
MPLNDQQRARLEKLRELRQQGIDPYPARSHRQLTAAQAHAVFTEREPHLGGQPDPEPVTLAGRVVSVRDMGRTVFSHIRD
GSGAIQLFLRREFVGDDQLAWFKRYVDLNDFVEADGHLFRTRTGEVSLEVHALRLLSKALNPPPDKWHGLTDVETRYRQR
YVDLMANPDTRQIFVTRARVIRAIRQYLDERGFLEVETPTLQPIYGGAAARPFTTYYHALDQTFYLRISDELYLKRLLVG
GYERVYEICKDFRNEGIDARHNPEFTMLEFYAAYADYHDIMQMCEELIVFAAREALGTLTFQWGDTVIDLTPPWARMSLR
EALLRFTGIDFLEVTDQPTLYARARALGADVEPTTVWPRILDELLKTFVRPRLVQPTFIYDYPVALSPLAKRKPEDPRLV
ERFQLFVGGLELANAYTELNDPLDQLYRFLEQARDRAQGDEEAMPIDEDFINALMYGMPPTGGFGLGIDRLVMLFTNRPT
IREVILFPQLRTKPQPLGLAEDLQPYLELVPGFQESVSTGSASPEGEAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-105 46
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002522097.1 lysyl-tRNA synthetase VFG1668 Protein 2e-105 46