Gene Information

Name : trd_1825 (trd_1825)
Accession : YP_002523024.1
Strain : Thermomicrobium roseum DSM 5159
Genome accession: NC_011959
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase aldh
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1835659 - 1837164 bp
Length : 1506 bp
Strand : -
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGACGACCGAAACCGGAATTCGCACCTACGGTCTGCTCATCGACGGCCAGTTCGTCCCCGCCGCGAGCGGTGAGACGTT
CCCGACCTACAATCCGGCGACGAACGAGGTCATCGGCTACGTCGCCAGGGCGAGTCGGGAGGATGTCGACCGTGCGGTCC
GCGCAGCCCGTCGTGCCTTCGACGAAGGCCCTTGGGGGCGTATGACGCCCAACGAGCGGGCCCGCCGCTTGCGCCGTGTC
GCCGAGATCCTCCGTGAGCGCGTCGACGAACTCGCGCGTCTGGAGACGCTGAACTGCGGGAAGATCATCGTCGAGTCGCG
GATGGACATCTTGTCTGCCGCCAACTGCTTCGACTATTACGCCAACCTGACAGGTCAGATCTGGGGCGAGACGATCCCGA
TGAACGGACCGCTCCTCGACTACACGGTTCGCGAACCGTACGGGGTGTGCGGACAGATCATTCCCTGGAACTTCCCCATC
CTCATGGCCGCATGGAAACTGGCACCGGCACTCGCGGCCGGAAATACGGTCGTTCTCAAGCCTGCCAGCTATACCCCGAT
CACCGCGCTCATCCTGGGGCAGATCTGCCTCGAAGCCGGTATCCCTGAAGGCGTTGTCAACGTCGTGACGGGGCCGGGCA
GCGAGGTCGGTGCCGCGATCTGCGAGCACCCGCTGGTCGACAAGATCGCCTTCACCGGCGAGACGGAGACCGGTCGCGAG
ATCTTGCGCCTGAGTGCGGGGACGATCAAGAAGGTTTCCCTCGAACTCGGTGGCAAGTCGCCGAACATCGTCTTCCCGGA
CGCCGACCTCGAAGAGGCGGTCAACGGCTCGCTGTTCGCTATCTTCACCAATGCGGGTCAGCGCTGCACGGCACGTACGC
GTCTCCTGCTGCACGAGTCGATCCATGATCAGTTCATGGATCTCTTTCTGCGCAAGGCATCCGCTCTGCGGATCGGTGAC
CCGTTGGATGAGCGCACCCAGCTCGGTCCGTTGGTCTCGCGCCGACAGTGCGAGCGCGTCCTGAGCTATGTCGAGCGCGC
CAAGGCGGAAGGGGCTGCGCTCCGCTTGGGTGGGAAGCGGCCGGACGACCCGGTGCTCCAGCGCGGGAACTTCGTCGAGC
CGACGATTTTCGACGAGGTGCAGCCCCAGATGACGATCGCCCGCGAGGAAGTCTTCGGTCCGGTGCTCGCCGTCATTCCG
TTCCGCACCGAGGACGAGGCGGTCGAGATCGCCAATGCGACGATCTACGGGCTCGCTGCCACGATCTGGACGAACGACAT
CAAGCGGGCACATCGCTTGGCGGCGCGGATCAAGGCCGGCAACATCAGCATCAACTATCCCGTCGTCAATCCACCGGAGG
CCCCCTTCGGCGGCTTCAAGCAGAGCGGTATCGGGCGGGAACTGTCGCGGCACGCGCTCGACCTCTACACGCAGGTCAAG
AATGTCGTCGTGGGGTTGAGCGAACAACGCTTCGACTGGTACGGAAACTGGCCACCTGGACGGTGA

Protein sequence :
MTTETGIRTYGLLIDGQFVPAASGETFPTYNPATNEVIGYVARASREDVDRAVRAARRAFDEGPWGRMTPNERARRLRRV
AEILRERVDELARLETLNCGKIIVESRMDILSAANCFDYYANLTGQIWGETIPMNGPLLDYTVREPYGVCGQIIPWNFPI
LMAAWKLAPALAAGNTVVLKPASYTPITALILGQICLEAGIPEGVVNVVTGPGSEVGAAICEHPLVDKIAFTGETETGRE
ILRLSAGTIKKVSLELGGKSPNIVFPDADLEEAVNGSLFAIFTNAGQRCTARTRLLLHESIHDQFMDLFLRKASALRIGD
PLDERTQLGPLVSRRQCERVLSYVERAKAEGAALRLGGKRPDDPVLQRGNFVEPTIFDEVQPQMTIAREEVFGPVLAVIP
FRTEDEAVEIANATIYGLAATIWTNDIKRAHRLAARIKAGNISINYPVVNPPEAPFGGFKQSGIGRELSRHALDLYTQVK
NVVVGLSEQRFDWYGNWPPGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-72 47
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-69 44
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 9e-70 44
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 9e-70 44
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 9e-70 44
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-69 44
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-76 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
trd_1825 YP_002523024.1 aldehyde dehydrogenase aldh VFG0082 Protein 8e-70 44