Gene Information

Name : serS (trd_1742)
Accession : YP_002522941.1
Strain : Thermomicrobium roseum DSM 5159
Genome accession: NC_011959
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1746722 - 1748059 bp
Length : 1338 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGACCTCAGGCTGATCCGAGAGCATCCGGACCTGGTGCGCGAGGCCTTGCGCAAGCTCAATACCGAGGCTCCGCT
CGACGAGATCCTGGAACTCGACGAGCGACGTCGCCAGCTGGTCGCTGAAGTCGAGCAGCTCAAGGCTCAACGCAACGCCG
AGTCCAAGCGGATCGGCCAGTTGCCAGCTGGGCCGGAGCGGGAAGCCACCATCGCCGCCATGCGTGCACTCGGCGACCGA
ATCGAGGCACTCGACCGCGAACTCGCCGCGATCGAAGAGCGGCTCCAGGCGCTGCTCTTGGAGGTTCCCAACCTGCCCGA
TCCCGATGTTCCCGTCGGCCCCGATGAAAGTGGCAACGTCGTCGTGCGTCACTGGGGAGAACCGCGACCGTTCGACTTCC
CGGTCAAGCCGCACTGGGAACTGGCGGAGGAGCTCGGGCTGATCGATTTCGCCCGCGGAGTCAAGATCGCGGGGAGTCGC
TTCTACGTGCTCCGCGGTGATCTCGCGCGGCTCCAGCGCGCCCTCATCGCCTGGATGATCGATCTCCACGTCAACGAGCA
TGGGTATTTGGAAGTCTATCCGCCGTTCCTCGTCCGCCGCGAGGCGATGATCGGGACGGGAAATCTCCCGAAGTTCGGGG
ACAATCTCTATCACGACGAGGAAACCGATCTCTGGCTGATTCCCACCGCTGAGGTGCCCGTTACCAATCTCTTCCGCGAC
GAAATCCTCCCGCCGGGTTCGCTCCCCATCTATCTCGTCGCGGCTACTCCTTGCTTCCGCAAGGAGAGAGTCTCAGCCGG
CCGCGATGTACGCGGAATCAAGCGCGTCCATCAGTTCGAGAAGGTGGAGATGGTCAAGTTCGTCGAGCCGGATCGCTCTG
ACGAGGAACTCCAGCGACTCGTCGCTGATGCCGAAGACGTGTTGCGCCGGCTGGAACTTCCCTACCGTGTCGTCCAAATG
TGCACTGGTGATCTTTCCTTCACGGCAGCCAAGAAGTTCGATCTCGAGGTCTGGGCACCTGGCTCCCAGGAGTGGCTGGA
GGTCTCGTCCTGCTCGAATTTCCGCGACTTCCAGGCCAGACGGGCCAATATCCGCTACCGGCCGAGCGAGGGAGCACGCC
CCCAGTTCGTGCACACGCTCAACGGATCGGGACTCGCTCTCCCCCGGACACTCATCGCGATCATGGAAAACTACCAGCAG
CCAGATGGGACGATCGAGATCCCAGCTGTCTTGCGCCCCTACATGGGTGGGCAACAGCGGATCGGCCGACAACCAGCTTA
TTGGGAACCAGCGCAGGCACGGCGCGCCCGCGAGCAGGCTCGGGCGGGGGACTCGTGA

Protein sequence :
MLDLRLIREHPDLVREALRKLNTEAPLDEILELDERRRQLVAEVEQLKAQRNAESKRIGQLPAGPEREATIAAMRALGDR
IEALDRELAAIEERLQALLLEVPNLPDPDVPVGPDESGNVVVRHWGEPRPFDFPVKPHWELAEELGLIDFARGVKIAGSR
FYVLRGDLARLQRALIAWMIDLHVNEHGYLEVYPPFLVRREAMIGTGNLPKFGDNLYHDEETDLWLIPTAEVPVTNLFRD
EILPPGSLPIYLVAATPCFRKERVSAGRDVRGIKRVHQFEKVEMVKFVEPDRSDEELQRLVADAEDVLRRLELPYRVVQM
CTGDLSFTAAKKFDLEVWAPGSQEWLEVSSCSNFRDFQARRANIRYRPSEGARPQFVHTLNGSGLALPRTLIAIMENYQQ
PDGTIEIPAVLRPYMGGQQRIGRQPAYWEPAQARRAREQARAGDS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 9e-104 51