Gene Information

Name : phoP (trd_1600)
Accession : YP_002522802.1
Strain : Thermomicrobium roseum DSM 5159
Genome accession: NC_011959
Putative virulence/resistance : Virulence
Product : alkaline phosphatase synthesis transcriptional regulatory protein PhoP
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1592372 - 1593091 bp
Length : 720 bp
Strand : -
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence :
GTGCCCACGATCTTGCTCGTCGAAGACGACGACACACTGCAAGCGACGATCCGCTACAACCTCGAGCGGGAGGGCTATTC
GGTCATCGTGGCCGACGCTGGCGAGGCCGCGCTCGAGCAGGCAGCGTTCGCCCGCCCCGACCTGGTCATTCTGGACATCA
TGCTGCCTGGTCTCGACGGCTTCCAGGTCTGCCGCCAACTGCGCGAGCAGAGCACTGTGCCGATCCTCATCCTGACGGCC
CGCGATACCGAGGTCGATCGCGTGCTCGGGCTGGAGCTGGGCGCCGACGACTACCTCACCAAACCCTTCTCGATGCGCGA
ACTCCTCGCGCGCGTCAAGGCGCTCCTCCGCCGCCGCGAGCTTTTGGCCAGAGAACTGGCTGCCGGCTTCTCCCCCGACA
TCCTGGAGATCGGCCCGTTGCGGATCGATCTCGAGCAACGGCGCGTCTGGCGCGAAGGGCGCGAGGTCGCGCTCAAGCCT
CGCGAGTTCGATTTGCTCGCCTACCTGGCCCGGCACCGGGAGCGCGTCTGCCGCTCCGAGGAACTGCTTCGCGCGGTCTG
GGGCTACGACACGTTCGGCGATTTCCGCACGCTGGCTGTGCACGTGCACGGGCTGCGCGAAAAGCTCGAGGACGATCCAC
GCCGTCCGCGGTTGATCGAGACGGTTCGGGGCATCGGCTATCGCTTGACCGCGCGCTCACCACAAGCGACACGCCGCTGA

Protein sequence :
MPTILLVEDDDTLQATIRYNLEREGYSVIVADAGEAALEQAAFARPDLVILDIMLPGLDGFQVCRQLREQSTVPILILTA
RDTEVDRVLGLELGADDYLTKPFSMRELLARVKALLRRRELLARELAAGFSPDILEIGPLRIDLEQRRVWREGREVALKP
REFDLLAYLARHRERVCRSEELLRAVWGYDTFGDFRTLAVHVHGLREKLEDDPRRPRLIETVRGIGYRLTARSPQATRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-28 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 9e-28 42
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-21 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002952.2859905.p0 Protein 5e-40 48
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_009641.5332272.p0 Protein 5e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_013450.8614421.p0 Protein 5e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_007793.3914279.p0 Protein 5e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_007622.3794472.p0 Protein 5e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002745.1124361.p0 Protein 5e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_009782.5559369.p0 Protein 5e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002951.3237708.p0 Protein 5e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_003923.1003749.p0 Protein 4e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002758.1121668.p0 Protein 5e-40 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_012469.1.7685629. Protein 8e-38 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP AE000516.2.gene3505. Protein 1e-35 46
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP BAC0083 Protein 1e-22 46
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP AE016830.1.gene1681. Protein 8e-37 45
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP BAC0638 Protein 1e-15 44
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP BAC0197 Protein 4e-21 43
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP HE999704.1.gene1528. Protein 2e-24 42
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP AF155139.2.orf0.gene Protein 4e-35 42
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP FJ349556.1.orf0.gene Protein 1e-34 42
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP BAC0347 Protein 3e-20 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP VFG1389 Protein 2e-25 47
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP VFG1390 Protein 3e-27 44
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP VFG1563 Protein 9e-29 42
phoP YP_002522802.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP VFG1702 Protein 4e-28 42