Gene Information

Name : leuS (trd_1240)
Accession : YP_002522448.1
Strain : Thermomicrobium roseum DSM 5159
Genome accession: NC_011959
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1224492 - 1226981 bp
Length : 2490 bp
Strand : -
Note : identified by match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396

DNA sequence :
ATGGCGACGACGCAGGAGGTCCGGCAGGCCGAGCGGTACGAGCCGCAAGTGATCGAGCCCAAATGGCAGCAAATCTGGGA
GGAGACGGGTATCTACTCCAACGTGCAGGAGGATCCCACTCGTCCCAAATGGTATCACCTGGTCATGTTCCCCTATCCAT
CAGGAAATTTGCACATCGGTCATTGGTTCTCCTACGCACCAGCTGATGCTGCTGCCCGCTACAAGCGGATGCGTGGTTAC
AATGTCCTCTTCCCATTTGGGTTCGACGCCTTCGGGTTGCCGGCAGAGAACGCGGCGATCAAACACGGTATTCATCCCCG
CGTGTGGACCATGCAGAACATCGCGCACATGAAAAAGCAGCTGCGCTCTCTCGGCGGGATGTTCGATTGGTCCAAGGAAG
TGATCACGTGCCTTCCCGAGTATTACCGCTGGAACCAGTGGTTCTTCCTCCAGTTCTACAAGCGGGGTCTGGCCTACCGT
GCCAAGGCGCCAGTCTGGTGGTGCCCGACATGCCAGACGGTGCTGGCCAATGAGCAAGTCATCGATGGACGCTGCGAGCG
CTGCAGCACCGAGGTGTACCGACGAGACCTCGAACAGTGGTTCTTGCGCATCACCGCGTATGCTGAAGAACTTCTGCGCT
TCGATGGGATCGACTGGCCGGAGCGCGTCATCACGATGCAGCGCAACTGGATCGGCCGATCGGAGGGCGCGCGGATCGTC
TTTCGCTCCGAGCAGGGAGACCCGATCGAAGTGTTCACGACACGCCCGGATACCCTCTGGGGGGCAACCTTCCTGGTGTT
GGCGCCGGAACATCCACTCGTGCAGAAGCTGACGACCCCTGAGCGGCGAGCCGAAGTCGAGGCGTACATCGATCAGGCGC
GGCGGCGGAGCGACATCGAGCGAACCTCGACTGAACGTGAAAAGACGGGTGTCTTCATCGGCGCGTACGCGATCAATCCG
GCGAACGGGCAGCGGATCCCCATCTGGATCGCCGATTACGTGCTCATGCAGTACGGTACCGGCGCCATCATGGCGGTGCC
GGCGCACGATCAGCGCGACTTCGAGTTCGCACGCGCCTTTGGCCTACCGATCGTGGTCGTGATCCAGCCACGAGACCGGA
CACTGGATCCGGCGACCATGGAAGAGGCATACGACGGCGAGGGCGTGATGGTCAATTCTGGTCCCTTCGACGGTACGCCG
ACGGAGGGAGGCGAAGCGATCCGCCGCGTCATCGCGTGGCTGGAGGAGCGAGGGGTGGGCCGAGGTGAAGTGACGTACCG
GTTGCGTGATTGGCTCATCTCGCGCCAGCGTTATTGGGGAACGCCCATCCCGATCGTCTATTGTGATCACTGCGGCATCG
TTCCGGTCCCAGAGGACCAGCTTCCCGTGCTGTTGCCGGAGGATGCGGAGTTCATGCCGACCGGGCAATCGCCCTTGATC
ACCCACGAGGCCTTCGTGAACACCACCTGTCCACAGTGCGGTGCTCCGGCACGGCGCGAAACCGATACGATGGATACCTT
CGTAGACTCGTCTTGGTACTGGTACCGCTATCTGAGTCCGCACGAGAACGAGCGGCCGTTCGATCCTGAAAAGGTCGCCT
ATTGGACGCCGGTCGATCAGTATACCGGTGGCATCGAGCACGCTATCCTGCATCTCCTCTACAGCCGCTTCTGGACGAAG
GCGCTCGCTGACCTCGGATTGGTGAATCATCGCGAGCCGTTTCTCCGGCTCTTCAATCACGGCGTCATTTTGGGCGAAGA
TGGCGAGAAGATGTCCAAGAGCCGCGGCAATGTCGTCGATCCCGACGACCTCGTGGCCCGGTTGGGAGCAGACACGGTTC
GACTGTACCTGATGTTCATCGGTCCTTGGTCGCAGGGCGGCCCGTGGAGTTCTCGCGGGGTCGCGGGTGTGCAGCGCTTC
TTGCAGCGTGTTTGGGCGCTCGTGACCGAAACGCTCGATGTGCCGGTCGACACAGCGGAGGACGAGCAGGCCCGAGCTTT
GCGCCGGCTCGTGCACCGGACGATCAAGCACGTGACCGACGACTTCGAAACGTTCAGCTTCAATACCGCAATCGCGCGGA
TGATGGAACTCGTGAACGAGTTGTCACGCTTGCGAGAGACCACGGTCGTGCGGATGCCGGTCTGGCGGGAGGCGTTGGAG
ACGCTCGTCCTCTTGCTCGCGCCGGGAGCACCGCATTTGGCGGAAGAGCTTTGGCAGAGACTCGGCAAGCCGTACAGCGT
GCACCAGCAATCCTGGCCGGCGTATGATCCAGCACTGGCGGCTGAGGAGACGGTCGAACTAGTGATTCAAGTGAATGGGC
GGGTGCGCGATCGCCTGCTGGTTCCGGCTGCGATCGATGAGGACGAAGCGGTGGCGCGAGCCCGCGAACTGGAGCGCGTG
CAGGCCTACTTGGCAGGGAAGCGGATCGAGCGAGTCGTCTACGTGCCCGGTCGGCTCGTGAACTTCGTTGTCAGTGACAC
GGCCGACTGA

Protein sequence :
MATTQEVRQAERYEPQVIEPKWQQIWEETGIYSNVQEDPTRPKWYHLVMFPYPSGNLHIGHWFSYAPADAAARYKRMRGY
NVLFPFGFDAFGLPAENAAIKHGIHPRVWTMQNIAHMKKQLRSLGGMFDWSKEVITCLPEYYRWNQWFFLQFYKRGLAYR
AKAPVWWCPTCQTVLANEQVIDGRCERCSTEVYRRDLEQWFLRITAYAEELLRFDGIDWPERVITMQRNWIGRSEGARIV
FRSEQGDPIEVFTTRPDTLWGATFLVLAPEHPLVQKLTTPERRAEVEAYIDQARRRSDIERTSTEREKTGVFIGAYAINP
ANGQRIPIWIADYVLMQYGTGAIMAVPAHDQRDFEFARAFGLPIVVVIQPRDRTLDPATMEEAYDGEGVMVNSGPFDGTP
TEGGEAIRRVIAWLEERGVGRGEVTYRLRDWLISRQRYWGTPIPIVYCDHCGIVPVPEDQLPVLLPEDAEFMPTGQSPLI
THEAFVNTTCPQCGAPARRETDTMDTFVDSSWYWYRYLSPHENERPFDPEKVAYWTPVDQYTGGIEHAILHLLYSRFWTK
ALADLGLVNHREPFLRLFNHGVILGEDGEKMSKSRGNVVDPDDLVARLGADTVRLYLMFIGPWSQGGPWSSRGVAGVQRF
LQRVWALVTETLDVPVDTAEDEQARALRRLVHRTIKHVTDDFETFSFNTAIARMMELVNELSRLRETTVVRMPVWREALE
TLVLLLAPGAPHLAEELWQRLGKPYSVHQQSWPAYDPALAAEETVELVIQVNGRVRDRLLVPAAIDEDEAVARARELERV
QAYLAGKRIERVVYVPGRLVNFVVSDTAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-165 45