Gene Information

Name : trd_1184 (trd_1184)
Accession : YP_002522393.1
Strain : Thermomicrobium roseum DSM 5159
Genome accession: NC_011959
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1173002 - 1174585 bp
Length : 1584 bp
Strand : +
Note : identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888

DNA sequence :
GTGTCACGATTGCTTCCCTCGACGACCAACCAGCACCCAACCTCTCCATCATTCGATAGTGTCGTCATCTTGGATTATGG
CTCGCAATACGCACAACTCATCGCGCGACGCGTGCGCGACGCCCATGTCTACTGTGAACTCGTTCCGTACGACACCGACT
GGTCAGCGCTGAAGCACCTTTCGCCGAAGGGGATCATCCTCTCCGGTGGACCAGCCAGCGTATACGAACCAGACGCCCCG
CAACTCCCCAGCTGGGTTCTCGAGAGTGGCCTCCCCGTCCTGGGGATCTGTTACGGCATGCAACTACTGGCCCACACATT
GGGCGGCAGGGTCGCGCCAGCGCAACGACGCGAATACGGCCCCGCAGTGGTCGAGCGTGTCGCAGACCATCCGATTTTCG
CCGGGCTTCCGGCGCGCTTCGATGTGTGGATGAGTCACGGCGATCGCATCGACGCGCTGCCTCCCGGATTCGAGGTGCTC
GCGCGCTCGGCCAACGCCCCCTACGCGGCAATGGCACGGGACCATCTCATCGGTCTCCAATTCCATCCGGAAGTCGCGCA
TACACCGCTCGGGAGCGTTATCTTGCGCAACTTTCTCTTCGATGTGTGTGGTTGCGCACCAACCTGGACAGCCGAGTCGT
TCGTCGAGCAGGCTATCCGCGAGATCAGGGAGCGGGTCGGCAAGGACCGGGTCCTGCTTGCGCTTTCCGGTGGCGTCGAT
TCGAGTGTCGCTGCGGCGCTGATCCACCGAGCGATCGGTGACCAGTTGACACCTGTTTTCGTCGATACTGGTTTGCTCCG
GGAAGGCGAAGCGGAGACGATTCGAGAAGTGTTCGGTCGGCACTTCCGCATGCCGCTCGTCGCGATCGACGCCCGTCAGC
GTTTCCTGGTTCGACTGCGCGGCGTAAGCGACCCGGAACAGAAACGCCGACTGATCGGCGAAGAGTTCGTCCGCGTTTTC
GAGGAAATCGCGCGCAGCCAAGGGCCATTCCGTTTCCTGGCACAAGGGACACTCTATCCTGACGTGATCGAGAGTGCTGC
TCCCGGAGCGTCGCGAACTGCCGCCAAGATCAAAACGCACCACAACGTCGGCGGTTTGCCCCAGGACCTCGAGTTCGAAC
TTCTCGAGCCGTTGCGCTATTTGTTCAAGGACGAGGTGCGCGCGATCGGACGCCTCCTCGGCCTTCCCGAGGAGATCGTG
CAGCGTCAACCGTTCCCTGGTCCTGGTTTGGCTGTGCGCATTCTCGGGGAAGTGACCGAGGAAGCGCTTGCGATCGTCCG
GCGAGCCGACACCATCGTCCGCGAAGAAGTCGAGGCTGCTGGACTCAGCGATGGACTCTGGCAGTTCTTCGCCGTCCTCC
TGCCAGTGCACTCGACAGGCGTGATGGGTGACCAACGCACGTACGCGCGGGTCATCGCGATCCGTGCCGTGACGAGTACG
GACGCCATGACCGCTGACTGGGCACGCTTGCCGCACGACCTTTTGGCCCGGCTCGCCAATCGGATCGTCAACGAAGTGCC
TGGTGTCAATCGCGTCGTCTACGACATCACCTCGAAGCCACCGGCCACCATCGAATGGGAGTGA

Protein sequence :
MSRLLPSTTNQHPTSPSFDSVVILDYGSQYAQLIARRVRDAHVYCELVPYDTDWSALKHLSPKGIILSGGPASVYEPDAP
QLPSWVLESGLPVLGICYGMQLLAHTLGGRVAPAQRREYGPAVVERVADHPIFAGLPARFDVWMSHGDRIDALPPGFEVL
ARSANAPYAAMARDHLIGLQFHPEVAHTPLGSVILRNFLFDVCGCAPTWTAESFVEQAIREIRERVGKDRVLLALSGGVD
SSVAAALIHRAIGDQLTPVFVDTGLLREGEAETIREVFGRHFRMPLVAIDARQRFLVRLRGVSDPEQKRRLIGEEFVRVF
EEIARSQGPFRFLAQGTLYPDVIESAAPGASRTAAKIKTHHNVGGLPQDLEFELLEPLRYLFKDEVRAIGRLLGLPEEIV
QRQPFPGPGLAVRILGEVTEEALAIVRRADTIVREEVEAAGLSDGLWQFFAVLLPVHSTGVMGDQRTYARVIAIRAVTST
DAMTADWARLPHDLLARLANRIVNEVPGVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-139 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-139 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-139 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-127 53