Gene Information

Name : trd_1035 (trd_1035)
Accession : YP_002522245.1
Strain : Thermomicrobium roseum DSM 5159
Genome accession: NC_011959
Putative virulence/resistance : Virulence
Product : ClpC ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1001854 - 1004307 bp
Length : 2454 bp
Strand : -
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGGCGGACAAGTTCGAGAAGTTCACGGAACGAGCCCGGAAAGTGCTCGCGCTGGCCCAAGAGGAAGCGCGACGCTTCAA
TCACAACTACATCGGCACCGAGCACCTGCTCCTCGGTCTCGTGCGCGAGGGGGAAGGTGTGGCGGCACGCGTGCTCCAGA
GCATGGGCGTGCAGCTGCCCAAGGTGCGTAGTGCCGTCGAGTTCATCATCGGGCGAGGGGAAAGCACGGTCGTCGGTGAG
ATCGGGCTGACCCCGCGCGCTCGCAAGGTGATCGAGTATGCCGTGGATGAAGCGCGCCGACTCGGGCACCACTACATCGG
AACGGAGCATCTGTTGCTCGGGCTCGTTCGCGAGGGTGAGGGTATCGCTGCGGGCGTGCTGGAGAGCCTCGGCGTGAACC
TGGAAAAGGTTCGCCAGCAGGTCCTACAGGTGCTCGCCCAAGGGACCGCCTACCAGCAGCGTGCGCAGCAGACCAAGACG
CCGTACCTCGATGCGCTCGGGTTCGACCTCACCGAGGCAGCTCGGCTCGGGAAGCTCGATCCAGTCATCGGTCGGCACAA
CGAAATCGAACGAGTGATGCAGATCCTCTCGCGCCGGACGAAGAACAACCCAGCCTTGATCGGTGAGCCAGGGGTCGGTA
AGACCGCGATCGTGGAGGGGCTGGCGCAGCGGATCGTTGCCGGTGACGTGCCGGAGCCACTGCAGGGCAAGCGCCTGGTC
GCCCTGGATATCGGTGCCTTGGTCGCTGGAACCAAGTATCGAGGCGAGTTCGAAGAGCGGCTGAAGAAGATCGTCGCGGA
GGTCAAGGAGTCTGGGACGATCCTGTTCATCGACGAACTCCACACGTTGGTCGGTGCCGGGGCGGCCGAGGGAGCAGTCG
ATGCGGCGAACATCTTGAAGCCCGCCTTGTCGCGCGGTGAGGTGCAAACGATCGGTGCCACGACGCTCGACGAGTATCGG
AAGTACATCGAGCGAGATGCAGCATTGGAGCGGCGATTCCAACCCGTCATCGTGAACGAGCCGACTGTCGAGGAAACGAT
CGAGATCCTGAAGGGGATCCGTGAGCGGTACGAGGAGCATCACAAGCTCAAGATTTCGGATGAGGCGCTTCACGCGGCCG
CTGTGTTGGCAGCACGTTACGTGACCGATCGGTTCTTGCCTGACAAGGCGATCGACCTGGTCGATGAGGCTGCATCGCGT
GTCCGGATGTACCGTTCTGCCTCACCACCGTCGCTCAAGGAGGCTCGTCGCGGGCTGGAGTCGCTGCGGCGCGAACTGGA
TGCCGCGGTGGCCAGCCAGGAGTTCGAGTTGGCTGCCGAGTTGCGCGAGCGCGAGCGACAGTTGGTGCATCGTATCCACG
AGCTGGAGCAGCATTGGCGCGAAGAACAAGGCCAGGAAGAGCCGATCGTCACGGAAGAGGATATTGCCCAGGTCGTCTCG
ATGTGGACGGGTATTCCGCTCACCCGTTTGCACACCGAGGAAAGCGAGCGCCTACTCCATATGGAGGAAGCGCTGCATGA
GCGTGTGATCGGGCAGGACGAAGCGATTTCGACGCTCGCTCGTGCTGTGCGCCGTGCTCGTGCGGGACTCAAGGACCCGC
GTCGACCGATCGGGACCTTCATCTTCCTCGGACCGACGGGAGTGGGGAAGACGCTGTTGGCGCGTGCGCTCGCTGAGTTC
ATGTTCGGTAGTGAGGATGCGCTGATCAAGATCGACATGAGCGAATTCATGGAGCGGCACACGGTGTCGCGTCTGGTGGG
GGCGCCGCCCGGCTACATCGGGTACGAGGAAGGTGGACAGCTGACGGAAGCCGTGCGCCGCAAGCCGTACTCGGTGATCC
TGCTCGACGAGATCGAGAAAGCGCATCCGGAAGCGTTCAACATCCTCCTCCAGATCATGGAGGATGGGAACCTGACGGAT
GCGAAAGGCCGGCGTGTCGACTTCCGGAACACCATCTTGATCATGACGTCGAACATCGGGGCGGAACTGATCCAGCGCGA
AGGTAGCCTCGGCTTTGCAGTGGCTGACGATCCGACCAAGAAGATGCAAGCTGATTACACTGCGATGAAGGACAAAGTCC
TCTCGCAGCTCAAGCAGACCTTCCGGCCGGAGTTCCTGAACCGAATCGATGCGGTCATCGTCTTCCATCCGCTGACGCCA
GAACACGTCCGACAGATCGTCGATCTGGAACTCAAGCGGATCCGCAAGCAGCTGGCGGAGCAACAGATCGGTCTCGAAGT
CACCGATGCGGCGAAGGATCTTTTGGCGAAGCGCGGCTACGACCGGCAGTTCGGAGCCCGTCCATTGCGGCGGATCATCC
AGAACTTGATCGAGGATCCGTTGGCGGAAGCGATCCTCGCTGGTCGGTTCAAGCCGGGGAGCACGGTCGTCATCAATGTC
CGCGACGACTTGCTCACCATCGAACCGGCAGAGGCACTGAGCACAGTCTCTTAA

Protein sequence :
MADKFEKFTERARKVLALAQEEARRFNHNYIGTEHLLLGLVREGEGVAARVLQSMGVQLPKVRSAVEFIIGRGESTVVGE
IGLTPRARKVIEYAVDEARRLGHHYIGTEHLLLGLVREGEGIAAGVLESLGVNLEKVRQQVLQVLAQGTAYQQRAQQTKT
PYLDALGFDLTEAARLGKLDPVIGRHNEIERVMQILSRRTKNNPALIGEPGVGKTAIVEGLAQRIVAGDVPEPLQGKRLV
ALDIGALVAGTKYRGEFEERLKKIVAEVKESGTILFIDELHTLVGAGAAEGAVDAANILKPALSRGEVQTIGATTLDEYR
KYIERDAALERRFQPVIVNEPTVEETIEILKGIRERYEEHHKLKISDEALHAAAVLAARYVTDRFLPDKAIDLVDEAASR
VRMYRSASPPSLKEARRGLESLRRELDAAVASQEFELAAELRERERQLVHRIHELEQHWREEQGQEEPIVTEEDIAQVVS
MWTGIPLTRLHTEESERLLHMEEALHERVIGQDEAISTLARAVRRARAGLKDPRRPIGTFIFLGPTGVGKTLLARALAEF
MFGSEDALIKIDMSEFMERHTVSRLVGAPPGYIGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEAFNILLQIMEDGNLTD
AKGRRVDFRNTILIMTSNIGAELIQREGSLGFAVADDPTKKMQADYTAMKDKVLSQLKQTFRPEFLNRIDAVIVFHPLTP
EHVRQIVDLELKRIRKQLAEQQIGLEVTDAAKDLLAKRGYDRQFGARPLRRIIQNLIEDPLAEAILAGRFKPGSTVVINV
RDDLLTIEPAEALSTVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
trd_1035 YP_002522245.1 ClpC ATPase VFG0079 Protein 0.0 61
trd_1035 YP_002522245.1 ClpC ATPase VFG0080 Protein 8e-136 51