Gene Information

Name : thyA (CCNA_02208)
Accession : YP_002517581.1
Strain : Caulobacter crescentus NA1000
Genome accession: NC_011916
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2355989 - 2356828 bp
Length : 840 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAGCACCGCCGTCCTCGACGCCCCCAAAGCCGCGACCGACCATCCCGAGCGGCAGTACCTGACCCTGCTGGCCGACAT
CCTGGAGAATGGCGTCCAGCGCGGCGACCGCACGGGCACGGGGACACTGGGCGTATTCGGCCGCCAGATCCGCTTTGACC
TGGCCAAGGGCTTCCCGGTCCTGACCACCAAGAAGCTGCACCTGCGCTCGATCATCATCGAGCTGCTGTGGTTCCTGAAG
GGCGACACCAACATCGCCTATCTCAAGGACAACGGCGTGCGCATCTGGGACGAGTGGGCCGACGAGAACGGCGACCTGGG
TCCCGTCTATGGCAAGCAGTGGCGCTCCTGGGCCACGCCTGACGGCCGGGTGATCGACCAGATCTCGGCCCTGGTCGAGA
ACCTGAAGGCCAACCCCAACAGCCGCCGCCACATCGTCACGGCCTGGAACCCGGCCGATGTCGACGACATGGCCCTGCCG
CCTTGCCACTGCCTGTTCCAGTTCTTCGTGGCGGATGGAAAACTGAGCTGCCAGCTCTACCAGCGCAGCGCCGACGTGTT
CTTAGGGGTGCCGTTCAACATCGCCAGCTACGCCCTGCTCACCCTGATGGTCGCCAAGGTCGTGGGCCTGGAGCCCGGCG
AGTTCGTCCACACCTTCGGCGACGCCCACCTCTATCTGAACCACCTGGATCAGGCCCGCGAGCAACTGACCCGCGAGCCC
TTCGACTTTCCCACGATGAAGATCGCCGACAAGCGCGACCTCTTCGGGTTCGAGTACGAGGACTTCACGCTGGAGGGCTA
TCAGGCCCACCCGCACATCAAGGCCGAGGTTTCGGTCTAG

Protein sequence :
MSTAVLDAPKAATDHPERQYLTLLADILENGVQRGDRTGTGTLGVFGRQIRFDLAKGFPVLTTKKLHLRSIIIELLWFLK
GDTNIAYLKDNGVRIWDEWADENGDLGPVYGKQWRSWATPDGRVIDQISALVENLKANPNSRRHIVTAWNPADVDDMALP
PCHCLFQFFVADGKLSCQLYQRSADVFLGVPFNIASYALLTLMVAKVVGLEPGEFVHTFGDAHLYLNHLDQAREQLTREP
FDFPTMKIADKRDLFGFEYEDFTLEGYQAHPHIKAEVSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 7e-81 62