Gene Information

Name : thiC (CCNA_02109)
Accession : YP_002517482.1
Strain : Caulobacter crescentus NA1000
Genome accession: NC_011916
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2258250 - 2260088 bp
Length : 1839 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATATCCAGAGCACCATCAAGGCCGTGGCCGAGACGATCTCGACCGGTCCGATCCCCGGCTCGCGCAAGGTCTATCA
GGCCGGCGAGCTGTTCCCCGAACTGCGCGTGCCGTTCCGCGAGGTGGCGGTCCATCCGTCGGCGAATGAGCCGCCGGTGA
CGATCTATGATCCGTCGGGCCCGTATAGCGACCCAGCCATCCAGATCGACATCGAGAAGGGCCTCCCGCGCACCCGCGAG
GCGCTGGTCGTGGCGCGCGGCGACGTCGAAGAGGTCGCCGATCCTCGCCAGGTGAAGCCCGAGGACAACGGCTTCGCCCA
AGGCAAGCACCTGGCCCCCGAATTCCCGGACACCGGCCGCAAGATCTACCGCGCCAAGCCGGGCAAGCTGGTCACCCAGC
TGGAATACGCCCGCGCCGGCATCATCACGGCCGAGATGGAATATGTGGCCATCCGCGAGAACCTGCGCCGCGAGCAGGAC
CGTCCGTGCGTGCGTGACGGCGAGGACTTCGGCGCCTCGATCCCCGACTTTGTGACGCCCGAGTTCGTGCGTCAGGAAAT
CGCCCGCGGCCGCGCGATCATTCCGGCCAACATCAACCACGGCGAGCTGGAGCCGATGGCGATCGGCCGCAACTTCCTGG
TCAAGATCAACGCCAATATCGGCAATTCGGCGGTGCTCTCGACCGTCGCCGACGAGGTCGACAAGCTGGTCTGGGCCACG
CGCTGGGGCGCCGACACGGTCATGGACCTGTCCACGGGTCGCAACATCCACAACATCCGCGACTGGATCATCCGTAACTC
GAGCGTGCCGATCGGCACCGTGCCGATCTATCAGGCGCTGGAGAAGGTCAACGGCGTGGCCGAGGACCTGAACTGGGAGG
TCTTCCGCGACACCCTGATCGAGCAGTGCGAGCAGGGCGTCGACTATTTCACGATCCACGCCGGCGTGCGCCTGCCGTTC
ATCCCGATGACCGCCAAGCGCGTCACCGGCATCGTGTCGCGCGGCGGCTCGATCATGGCCAAGTGGTGCCTGGCGCACCA
CAAGGAGAACTTCCTCTACGAGCGCTTCGACGAGATCTGTGAGATCATGCGCGCCTATGACGTGTCGTTCTCGCTGGGCG
ATGGTCTGCGTCCCGGCTCGACCGCCGACGCCAACGACGAGGCCCAGTTCTCGGAGCTGCGCACCCTGGGCGAGCTGACC
AAGGTGGCCTGGAAGCACGGCGTCCAGGTGATGATCGAAGGGCCGGGCCACGTGGCCATGCACAAGATCAAGGCCAATAT
GGATGAGCAGCTGAAGCACTGCCACGAGGCCCCGTTCTACACCCTCGGCCCGTTGACCACGGACATCGCGCCTGGCTACG
ACCACATCACCTCGGCCATCGGGGCGGCGATGATCGGCTGGTTCGGCACGGCGATGCTCTGCTACGTCACGCCCAAGGAG
CACCTGGGCCTGCCGGACCGCGACGACGTGAAGACCGGCGTCATCACCTACAAGCTGGCCGCTCACGCCGCTGACCTCGC
CAAGGGCCATCCGGGCGCTGCGATGTGGGACGACGCCATCAGCCGCGCGCGGTTCGAGTTCCGCTGGGAGGACCAGTTCA
ACCTGGGCCTCGACCCGGAAACCGCCCGCAAGTTCCACGACGAGACCCTGCCCAAGGAGGCGCACAAGACCGCGCACTTC
TGCTCGATGTGCGGACCCAAGTTCTGCTCGATGAAGATCAGCCAGGAGGTTCGAGACTTCGCGGCCGGCAAGGCGCCCAA
CAGCGCCGAACTGGGCATGGCCGAGATGAGCGAGAAGTTCCGCGAGCAGGGCTCGGAGATCTATCTGAAGACCGAGTGA

Protein sequence :
MNIQSTIKAVAETISTGPIPGSRKVYQAGELFPELRVPFREVAVHPSANEPPVTIYDPSGPYSDPAIQIDIEKGLPRTRE
ALVVARGDVEEVADPRQVKPEDNGFAQGKHLAPEFPDTGRKIYRAKPGKLVTQLEYARAGIITAEMEYVAIRENLRREQD
RPCVRDGEDFGASIPDFVTPEFVRQEIARGRAIIPANINHGELEPMAIGRNFLVKINANIGNSAVLSTVADEVDKLVWAT
RWGADTVMDLSTGRNIHNIRDWIIRNSSVPIGTVPIYQALEKVNGVAEDLNWEVFRDTLIEQCEQGVDYFTIHAGVRLPF
IPMTAKRVTGIVSRGGSIMAKWCLAHHKENFLYERFDEICEIMRAYDVSFSLGDGLRPGSTADANDEAQFSELRTLGELT
KVAWKHGVQVMIEGPGHVAMHKIKANMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKE
HLGLPDRDDVKTGVITYKLAAHAADLAKGHPGAAMWDDAISRARFEFRWEDQFNLGLDPETARKFHDETLPKEAHKTAHF
CSMCGPKFCSMKISQEVRDFAAGKAPNSAELGMAEMSEKFREQGSEIYLKTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 67
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 67
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 65