Gene Information

Name : smpB (Tgr7_0962)
Accession : YP_002513037.1
Strain : Thioalkalivibrio sulfidophilus HL-EbGR7
Genome accession: NC_011901
Putative virulence/resistance : Unknown
Product : ssrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1040326 - 1040799 bp
Length : 474 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGTCGAAACAGGCCAAACAAGCGGGCACCAGCACCATTGCGCTCAACAAGAAGGCGCGCCACGAATACTTCATCGAGGA
ACGCTTCGAGGCGGGCCTCGCCCTGGAGGGCTGGGAGGTCAAGAGCCTGCGAGACGGGCGCGTGCAGCTCAACGAGAGCT
ACGTGCTCATCAAGGACGGCGAGGCCTGGCTGTTCGGCGCCCACATCAGCCCCCTGCCCACCGCCTCCACCCACATCCAC
CCCGACCCCATGCGCAGCCGCAAGCTGCTGCTGCACAAGGAAGAACTCAACAAGCTCATCGGCCAGGTGGAGCGCAAGGG
CTACACCCTGACCCCGCTCGCGCTCTACTGGAAGCGCGGCCGGGCTAAGCTGGAGATCGGCCTCGCCAAGGGCAAGAAGG
AACATGACAAGCGCGCCACCATCAAGGACCGGGACTGGCAGCGGGAGAAGGAACGGGCGCTGAAGAAGGGTTGA

Protein sequence :
MSKQAKQAGTSTIALNKKARHEYFIEERFEAGLALEGWEVKSLRDGRVQLNESYVLIKDGEAWLFGAHISPLPTASTHIH
PDPMRSRKLLLHKEELNKLIGQVERKGYTLTPLALYWKRGRAKLEIGLAKGKKEHDKRATIKDRDWQREKERALKKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 8e-38 59
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-21 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-19 44