Gene Information

Name : Tgr7_2823 (Tgr7_2823)
Accession : YP_002514883.1
Strain : Thioalkalivibrio sulfidophilus HL-EbGR7
Genome accession: NC_011901
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 2965656 - 2967671 bp
Length : 2016 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGCGTGTTTCTGTGCGAAAAGCCTTCGCAAGGCAAGGACATCGCCAGGGTGTTGGGCGCCCGGCAGCGCGGCAACGG
CTGCTACAGCGGTTCGGGTATCACGGTGACATGGTGCATCGGCCATCTTGTCGAGGCGGCACCGCCGGAAACCTACGGCG
AGCAGTACAAGCAGTGGTCCATCGAGCAGTTGCCTATTCTTCCAGAGCGCTGGCGCATCGAGGTCAAGGCCAAGACCGCC
GCGCAGTTCAAGATCGTGAAGCAGTTCGTCGCCCAGGCCGGCGAGCTGGTGATCGCCACCGACGCCGACCGCGAAGGCGA
AATGATCGCGCGCGAGATCATCGATCTGTGCGGCTACCGTGGCCCGATCCAGAGGCTGTGGCTGTCGGCGCTCAACGATG
CGTCGATCCGCAAGGCGCTGACTCAACTCAAGCCGGGTGGCGAAACGCTGCCACTGTATTTTTCCGCACTGGCCCGTTCG
CGCGCGGATTGGCTGATCGGCATGAACCTGAGCCGCCTGTTCACGGTGCTGGGTCGGCGGTCTGGGTATCAGGGCGTGCT
GTCGGTCGGTCGCGTACAGACACCGACACTGAAACTGGTGGTGGACCGCGACCGCGAGATCGCACGCTTCGTCTCCGTAC
CGTATTGGACCATCGACGTCACGCTGTCCCACGCGGGCCAGTCCTTCGCGGCAAGCTGGATGCCGCCCGACGGCACCACG
GATGCAGCCGGTCGCTGCCTGCAGCAGCCAGTGGCGCAGCAGGCTGCCGACCGCATCCGTGCGGGTCGTGAATCGAAGGT
GCTGTCGGTGGAAACCGAGCGTGTGCGCGAAGCCGCACCGCTGCCGTTCGACCTCGGCACCTTGCAGGAAGTGTGTTCGC
GGCAACTCGGGCTGGACGTACAGGAGACGCTGGACATCGCGCAGTCCTTGTACGAAACGCACAAGGCGACGACTTATCCG
CGCAGTGACTCCGGCTACCTGCCCGAGAGCATGCTGGCCGAAGTGCCGACCGTGCTCGACGCGCTGCTCGCCACCGATCC
CGGCCTACGCCCGTTGATCGACCGGCTCGACAGGACACAGCGCTCGCGCGTCTGGAACGACAGCAAGATAACGGCGCACC
ACGGCATCATTCCCACGCTGGAGCCTGCGAACCTCTCGGCCATGTCGGAGAAGGAGCTGGCGGTATACGCGCTGATCCGG
GCGCACTACCTGGCGCAGTTCCTGCCGCATCACGAATTCGACCGCACACTGGTGATGCTCGACTGTGCAGGGCAATCGTT
ACAGGCCGTCGGCAAACGGGTGATCGTGCCTGGCTGGCACCTGGCGCTCCCCGGCAAGGGGCAGGATGCGGCGGACGACG
AGCCGGCCCAGCGCAGCCAGATCCTGCCGCCGCTGGACACCGGAGCGCGCTGCGGTGTCCAGCAGGTCGAACTGAAGGCA
CTGAAGACGCTGCCCCCCAAGCCTTACACCCAGGGCGAATTGATCAAGGCGATGAAGGGTGTCGCCAAGCTGGTCACCGA
TCCACGGCTGAAGCAGAAGCTGAAGGAGACGACGGGCATCGGCACCGAAGCCACGCGCGCCGGCATCATCAACGGCCTGT
TGGCTCGCGGCTATCTGGTGAAGAAGGGTCGCGCCATCCGCGCGTCGGATGCTGCCTTCACACTCATCGACGCGGTGCCG
GCGGCGATCACCGATCCCGGCACGACGGCGATCTGGGAACAGGCGCTGGACATGATCGAGGCCGGCCAGATGACGCTGGA
CACCTTCATCAACAAGCAATCGGCCTGGGTCGCGCAGTTGGTTCAGCAATATCGAGGCACCGTCCTGTCGATCAAGCTGC
CCGAAGGGCCGGCCTGCCCGGTATGCGGTGCGGCGACGCGCCAGCGCAACGGCAAGAACGGTGCCTTCTGGTCGTGCAGC
CGCTATCCCGACTGCAAGGGCACGCTGCCGGCCGAATCCTCGACGGGCAGGCGCAGGGCTTCGCGCCAGCGGCGCGCTGC
GCCCAAGGCATCCTGA

Protein sequence :
MRVFLCEKPSQGKDIARVLGARQRGNGCYSGSGITVTWCIGHLVEAAPPETYGEQYKQWSIEQLPILPERWRIEVKAKTA
AQFKIVKQFVAQAGELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALTQLKPGGETLPLYFSALARS
RADWLIGMNLSRLFTVLGRRSGYQGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWTIDVTLSHAGQSFAASWMPPDGTT
DAAGRCLQQPVAQQAADRIRAGRESKVLSVETERVREAAPLPFDLGTLQEVCSRQLGLDVQETLDIAQSLYETHKATTYP
RSDSGYLPESMLAEVPTVLDALLATDPGLRPLIDRLDRTQRSRVWNDSKITAHHGIIPTLEPANLSAMSEKELAVYALIR
AHYLAQFLPHHEFDRTLVMLDCAGQSLQAVGKRVIVPGWHLALPGKGQDAADDEPAQRSQILPPLDTGARCGVQQVELKA
LKTLPPKPYTQGELIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAGIINGLLARGYLVKKGRAIRASDAAFTLIDAVP
AAITDPGTTAIWEQALDMIEAGQMTLDTFINKQSAWVAQLVQQYRGTVLSIKLPEGPACPVCGAATRQRNGKNGAFWSCS
RYPDCKGTLPAESSTGRRRASRQRRAAPKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 79
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 76
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 67
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 4e-172 52
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 5e-172 52
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 5e-172 52
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 7e-170 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-165 50
topB AAW83109.1 TopB Not tested GGI Protein 2e-125 41