Gene Information

Name : Tgr7_2810 (Tgr7_2810)
Accession : YP_002514870.1
Strain : Thioalkalivibrio sulfidophilus HL-EbGR7
Genome accession: NC_011901
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2953455 - 2955857 bp
Length : 2403 bp
Strand : +
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: sfr:Sf

DNA sequence :
ATGAGCGAACACAGCCCAGAAGGGTGTGACTGTGCGGCCACACCGATCATTCCAGCCGCAACGCAAGCCCGACCTATCGC
CGAATCGGCCGAGGCTGTCTACCGCATCGAGAACATGGATTGCCCGACTGAAGAGGCACTGATCCGAAGCAAACTAGGCG
GCCTATCGGGTGTGATCGGACTCGACTTCAATCTGATGCAGCGTACCTTGGCGGTGCGACATGAACTGCCTTCGCTGTTG
CCGGTTGAACAAGCCCTGAAGGCGATCGGCATGCAGGCTGTACGCATGGATGCAGCCGTGGCCGGGCAGACCACCAGATT
ATCCATTGCCAAGATGGATTGCCCGACCGAAGAAACGCTGATCCGTAACAAGCTGGCAACCGTGGCCGGCGTCTCCTATC
TCGATTTCAATCTGGTGCAACGCACCCTGTCCGTGCGTCATGCCGACCACGCGCTGCCAAATGTGCTCGCCGCACTGCAA
GCGCTTGGATTCGAGGCACAGGTGCTTGAGGCAGCGGACACCACTACATCGGCTGCCCCGGCGACAGCACCTACCAAGTG
GTGGCCGCTTGCCGTCTCCCTAGTGGCGGCATCGGCAGCGGAGGTCGTCTACTGGCTTCATGACGGCAACCACTGGTCAG
TCATCGCTCTGGCGCTCGTCGCCATTTTCACGGGAGGTCTCTCCACCTACAAGAAGGGCTGGTTTGCGCTCAAGAACCTC
AATCTCAACATGAACGCCCTGATGTCGATTGCCGTCACGGGCGCAATGCTGATCGGTCACTGGCCGGAAGCGGCGATGGT
GATGGCGCTTTTCACGCTGGCCGAGGTGATCGAAGCCAGATCGCTGGATCGCGCCCGTAACGCCATACGCGGGCTACTCG
ACTTGGCCCCGGAAAAGGCCACCGTGCGACAACCCGACGACACATGGCGCGATGTGGACGCCAAGCAGGTCGCCATTGGC
GCCCGTGTTCGAGTCAAACCGGGAGAACGGATCGCCCTCGACGGCGAAATACTGGTAGGACATTCCACGGTCAATCAGGC
GCCGATCACCGGCGAAAGCCTCCCGGTTGAAAAGACGCTTGGCGATCCGGTGTTCGCCGGCACGATCAACGAATCCGGTT
CGTTCGAATACCGCGTCACAGCCATAGCCACCAACTCTACGCTAGCCCGCATCATCCATGCCGTAGAGGCCGCCCAAGGC
AGCCGTGCGCCGACCCAGCGCTTTGTGGATCAGTTTGCCCGCTGGTACACCCCAATCGTCTTCGTCGTAGCCATCGTCGT
CGCATTGGTACCACCGCTGTTCATGGGCGCAGCGTGGCTGGACTGGATTTACCGCGCGCTGGTTCTGTTGGTCGTTGCCT
GTCCGTGCGCTCTCGTGATTTCCACGCCTGTCACCATCGTCAGCGGATTGGCCGCCGCTGCGCGCCGCGGCATTCTCATC
AAGGGTGGTGTCTATCTGGAAGAAGGCCGCAAGCTGCGCTGGCTGGCGCTGGACAAGACCGGCACGATCACGCATGGCAA
GCCAGCGCAATCCGATTTCGTGGCGTGGGCCAATGCACAGCCTAGCGACAGCCGCAGAATTGCCGCGAGTCTGGCGGCTC
GCTCGGACCATCCCGTATCCAAGGCTGTGGCGCAAGCCGCCAAGGCTGATGGGGTCGCCTTGCTCGAAGTTGCCGATTTC
ACCGCATTGCCCGGCAGAGGGGTGAGTGGCCGCATCGACGGTGAGACCTATCACCTCGGCAACCATCGGATGCTCGAAGA
GCTGGGGCACTGCACGCCGGAACTGGAACAGCGCATCTCCGCGATGGAAGTCGAAGGCAAGACCGTGGTGACGCTGGTAT
GTACAAGTGGCGCGCAAGCCCTTATCGCGGTAGCGGACACCATCAAGGACAGCAGCACGAGCGCCATCGAGGATCTGCAT
GCCCTGGGCATCAAAACCATGATGCTGACCGGCGACAACCCACATACGGCACAGGCCATTGCCAGGCAAGCCGGCATCGA
CCGCGCGCAGGGCAACCTATTGCCAGACGACAAACTGCGCGAGATCGAACAACTGGCGCGGACGGGGAAGGTCGGCATGG
TGGGCGACGGCATCAACGATGCGCCCGCCTTGGCTCGCGCTGACATCGGCTTCGCGATGGGTGCCGCCGGTACCGACACG
GCCATCGAAACGGCTGACGTAGCGCTGATGGATGACGACCTGCGCAAGATTCCGACGTTCATTCGCCTGTCACGTGCAAC
CGCGCGCGTGCTGACGCAGAACATCGTGCTGGCGCTTGGCATCAAGGCGGTCTTTCTTGCGCTCACTTTCTCGGGACACG
CCACGATGTGGATGGCGGTGTTCGCCGACATGGGCGCAAGCCTGATTGTGGTGCTCAACGGATTGCGTTTGCTGCGCCAC
TGA

Protein sequence :
MSEHSPEGCDCAATPIIPAATQARPIAESAEAVYRIENMDCPTEEALIRSKLGGLSGVIGLDFNLMQRTLAVRHELPSLL
PVEQALKAIGMQAVRMDAAVAGQTTRLSIAKMDCPTEETLIRNKLATVAGVSYLDFNLVQRTLSVRHADHALPNVLAALQ
ALGFEAQVLEAADTTTSAAPATAPTKWWPLAVSLVAASAAEVVYWLHDGNHWSVIALALVAIFTGGLSTYKKGWFALKNL
NLNMNALMSIAVTGAMLIGHWPEAAMVMALFTLAEVIEARSLDRARNAIRGLLDLAPEKATVRQPDDTWRDVDAKQVAIG
ARVRVKPGERIALDGEILVGHSTVNQAPITGESLPVEKTLGDPVFAGTINESGSFEYRVTAIATNSTLARIIHAVEAAQG
SRAPTQRFVDQFARWYTPIVFVVAIVVALVPPLFMGAAWLDWIYRALVLLVVACPCALVISTPVTIVSGLAAAARRGILI
KGGVYLEEGRKLRWLALDKTGTITHGKPAQSDFVAWANAQPSDSRRIAASLAARSDHPVSKAVAQAAKADGVALLEVADF
TALPGRGVSGRIDGETYHLGNHRMLEELGHCTPELEQRISAMEVEGKTVVTLVCTSGAQALIAVADTIKDSSTSAIEDLH
ALGIKTMMLTGDNPHTAQAIARQAGIDRAQGNLLPDDKLREIEQLARTGKVGMVGDGINDAPALARADIGFAMGAAGTDT
AIETADVALMDDDLRKIPTFIRLSRATARVLTQNIVLALGIKAVFLALTFSGHATMWMAVFADMGASLIVVLNGLRLLRH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 71
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-103 47
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-103 47
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-105 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tgr7_2810 YP_002514870.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 74