Gene Information

Name : Tgr7_1966 (Tgr7_1966)
Accession : YP_002514034.1
Strain : Thioalkalivibrio sulfidophilus HL-EbGR7
Genome accession: NC_011901
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 2086664 - 2088046 bp
Length : 1383 bp
Strand : -
Note : KEGG: noc:Noc_2356 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN

DNA sequence :
ATGCCGGTGACGGCCATGGCGCTCCCTGAGGGCCTGGATCCCGAGCTGCGTCTGGCCCGGCTGCGGGACAGCCTGCGCCG
GGGCGCCCGGCGCGTGGAGCAGGCCCGACCGCTGACCGCCGAAGGGCGCCTGGTGCGCATGGTGGGCCTGACCCTGGAGG
CCGAGGGGGTGCGCATGCCCGTGGGTGGACGTTGCCGGGTGGTGAGCGCGGGCGGCGCCGAGGTGGAGGCCGAGGTGGTG
GGTTTCTCCGGCGAACGGGTGTTCCTCATGCCCGTGGGCGACATCAGCGGGCTCACCCCCAATGCCCGGGTGATCCCCAC
CCAGCATGCCCGTGAGGCCCGGGTGGGCGAGGCCCTGCTGGGTCGCGTACTGGACGGTGCGGGCCGGCCCCTGGACGGTC
TGCCGCCTCCGGATTGCGAGGCCAGCGTGTCCTTGAACGGCCGTCCCCTCAACCCCCTGGCGCGGCGTCCCATCCACGAG
CCCCTGGACGTGGGCGTGCGCGCCATCAACGGCCTGCTCACCGTGGGCCGCGGCCAGCGCATGGGCCTGTTCGCCGGCAG
CGGCGTGGGCAAGAGCGTGCTGCTGGGCATGATGACCCGCTACACCAATGCCGATGTCACGGTGGTGGGGCTGATCGGCG
AGCGTGGCCGGGAAGTGAACGAATTCGTGCAGAACATCCTCGGTCCCGAGGGCATGGCCCGGGCGGTGGTGGTGGCGGTA
CCCGCCGACCATCCGCCGCTGATGCGCCTGCACGGCGCCATGCTGGCCACCTCCATCGCCGAGTACTTCCGGGACCAGGG
CCTGAACGTGCTGCTGCTCATGGATTCCCTGACCCGTTTCGCCCAGGCCCAGCGCGAGATCTCGCTGGCCATCGGCGAAC
CGCCTGCCACCAAGGGTTATACGCCGTCCGTGTTCGCGCGCCTGCCGCACCTGGTGGAGCGTGCCGGCAACAGCGACCGG
GGCGAGGGCACCATGACCGCCTTCTACACGGTGCTCACCGAGGGCGACGACCAGAACGACCCCATCGCCGATGCGGCCCG
GGCGATCCTCGATGGACACGTGGTGCTGTCCCGGCGCATCGCCGAGGCCGGCCGCTATCCCGCCATCGACATCGAGGCCT
CCGTGAGCCGGCTCATGAACGAGATCGCCGACCCGGGCCAGATCCAGGCCGCGCGCCTGTTCAAGCAGATCTACGCCACC
TACCAGCAGAACCGGGACCTGATCAGCGTCGGCGCCTACCAGAAGGGCGCCGACCCCCGGGTGGACGCCGCCATCCAGTA
CTATCCTCACCTCGAGCAGTACCTCTCCCAGGACATGCGCGAGGCCGTGGATTTCAAGGAAAGCCTGCGGGCGCTGGACG
CGCTGATGAACGAGGAGGCGTGA

Protein sequence :
MPVTAMALPEGLDPELRLARLRDSLRRGARRVEQARPLTAEGRLVRMVGLTLEAEGVRMPVGGRCRVVSAGGAEVEAEVV
GFSGERVFLMPVGDISGLTPNARVIPTQHAREARVGEALLGRVLDGAGRPLDGLPPPDCEASVSLNGRPLNPLARRPIHE
PLDVGVRAINGLLTVGRGQRMGLFAGSGVGKSVLLGMMTRYTNADVTVVGLIGERGREVNEFVQNILGPEGMARAVVVAV
PADHPPLMRLHGAMLATSIAEYFRDQGLNVLLLMDSLTRFAQAQREISLAIGEPPATKGYTPSVFARLPHLVERAGNSDR
GEGTMTAFYTVLTEGDDQNDPIADAARAILDGHVVLSRRIAEAGRYPAIDIEASVSRLMNEIADPGQIQAARLFKQIYAT
YQQNRDLISVGAYQKGADPRVDAAIQYYPHLEQYLSQDMREAVDFKESLRALDALMNEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-82 53
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-79 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-74 47
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-74 47
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-72 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-72 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-62 47
escN AAC31513.1 L0034 Virulence LEE Protein 2e-72 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-72 47
escN AAK26715.1 EscN Virulence LEE Protein 1e-71 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-72 47
escN AAL57542.1 EscN Virulence LEE Protein 1e-71 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-72 47
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-71 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-72 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-71 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 7e-72 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 8e-72 47
escN AAC38383.1 EscN Virulence LEE Protein 4e-72 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-82 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 9e-84 46
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-83 46
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 46
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-82 46
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-80 46
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-83 46
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-80 46
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-83 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-62 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-72 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-72 46
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 8e-72 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-62 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-63 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-63 46
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-70 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-64 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-68 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 6e-64 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 4e-64 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-64 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-59 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-59 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-64 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-64 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-64 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-64 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-60 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG1254 Protein 1e-118 64
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG2499 Protein 2e-114 62
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG2331 Protein 6e-113 61
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG0390 Protein 3e-80 50
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG0048 Protein 2e-79 49
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG0192 Protein 4e-84 48
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG2144 Protein 1e-81 48
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG0515 Protein 3e-72 47
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG0812 Protein 1e-72 47
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG0730 Protein 2e-72 47
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG2459 Protein 4e-64 43
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG0555 Protein 1e-64 42
Tgr7_1966 YP_002514034.1 flagellar biosynthesis/type III secretory pathway ATPase, FliI/YscN VFG1778 Protein 3e-61 41