Gene Information

Name : wze (SPN23F_03210)
Accession : YP_002510377.1
Strain : Streptococcus pneumoniae ATCC 700669
Genome accession: NC_011900
Putative virulence/resistance : Virulence
Product : capsule biosynthesis tyrosine-protein kinase Wze
Function : -
COG functional category : D : Cell cycle control, cell division, chromosome partitioning
COG ID : COG0489
EC number : 2.7.10.1
Position : 306448 - 307137 bp
Length : 690 bp
Strand : +
Note : -

DNA sequence : 
ATGCCAACATTAGAAATCTCACAGGCAAAATTGGATTCTGTAAAAAAGGCAGAGGAATATTATAACGCTTTGTGCACGAA
CCTACAGTTAAGTGGAGATGGTTTGAAAGTATTTTCTATCACTTCTGTGAAAATAGGAGAAGGAAAATCAACGACTTCCG
CCAATATCGCTTGGGCTTTTGCGCGTGCAGGTTACAAAACGCTGCTGATTGATGGAGATATTCGCAATTCTGTTATGTTA
GGTGTCTTTAAAGCAAGGAATAAGATTACAGGCCTGACAGAATTTTTATCAGGAACTACAGACCTATCACAAGGGCTTTG
TGATACCAATATCGAAAATCTCTTTGTAATTCAGGCTGGCTCTGTGTCACCGAATCCGACAGCTCTTCTTCAAAGTAAGA
ATTTCACTACAATGCTTGAAACCTTGCGTAAATATTTTGACTACATCATTGTAGATACTGCTCCTGTTGGTGTCGTGATT
GATGCGGCTATTATTACGCGAAACTGCGATGCTTCTATTTTAGTGACGGAGGCAGGTGAAATAAATCGACGGGATATTCA
AAAAGCAAAAGAACAGTTGGAACACACAGGAAAGCCGTTTTTGGGAATTGTGTTGAATAAATTCGATACTTCAGTAGACA
AATACGGTTCTTATGGAAATTATGGAAATTACGGGAAAAATAAAAAATAG

Protein sequence : 
MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVKIGEGKSTTSANIAWAFARAGYKTLLIDGDIRNSVML
GVFKARNKITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
DAAIITRNCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDKYGSYGNYGNYGKNKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpsFD YP_006310771.1 putative autophosphorylating protein tyrosine kinase Not tested FWisland_4 Protein 1e-65 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wze YP_002510377.1 capsule biosynthesis tyrosine-protein kinase Wze VFG1368 Protein 7e-82 81
wze YP_002510377.1 capsule biosynthesis tyrosine-protein kinase Wze VFG1349 Protein 8e-57 56
wze YP_002510377.1 capsule biosynthesis tyrosine-protein kinase Wze VFG1298 Protein 2e-28 42