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Name : pyk (SPN23F_08190) Accession : YP_002510826.1 Strain : Streptococcus pneumoniae ATCC 700669 Genome accession: NC_011900 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 805087 - 806592 bp Length : 1506 bp Strand : + Note : catalyzes the formation of phosphoenolpyruvate from pyruvate DNA sequence : ATGAACAAACGTGTAAAAATCGTTGCAACTTTGGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTCGGTGAGGACGG ATACTGGGGTGAAAAACTTGATGTTGAAGCTTCAGCTAAAAACATTGCTAAATTGATTGAAGCTGGTGCTAACACATTCC GATTCAACTTCTCACACGGCGACCACCAAGAACAAGGTGAGCGTATGGCAACTGTTAAACTTGCGGAAAAAATTGCAGGT AAAAAAGTTGGTTTCCTTCTTGACACAAAAGGACCTGAAATCCGTACAGAATTGTTCGAAGGTGAAGCTAAAGAATATTC ATACAAAACTAGTGAAAAAATTCGTGTTGCAACTAAACAAGGAATCAAATCAACTCGTGAAGTGATTGCGTTGAACGTTG CTGGTGCTCTTGATATCTATGATGATGTTGAAGTTGGTCGTCAAGTTTTGGTTGACGATGGTAAACTTGGTCTTCGTGTG GTTGCTAAAGATGATGCAACTCGTGAATTTGAAGTTGAAGTTGAAAACGATGGTATCATCGCTAAACAAAAAGGTGTGAA CATCCCTAACACTAAAATTCCTTTCCCAGCTCTTGCTGAACGCGATAACGACGATATCCGTTTCGGTCTTGAACAAGGTA TCAACTTCATCGCAATTTCATTCGTACGTACTGCAAAAGATGTGAACGAAGTTCGTGCAATCTGTGAAGAAACTGGAAAC GGACATGTTCAATTGTTCGCTAAAATCGAAAACCAACAAGGTATCGATAACTTAGACGAAATCATCGAAGCAGCTGATGG TATTATGATTGCTCGTGGTGATATGGGTATCGAAGTACCGTTCGAAATGGTTCCAGTTTATCAAAAAATGATTATCAAGA AAGTCAATGCTGCAGGTAAAGTTGTTATCACTGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCAACTCGT TCAGAAGTATCAGACGTATTCAACGCTGTTATCGACGGAACTGACGCTACAATGCTGTCAGGCGAGTCTGCAAACGGTAA ATACCCACTCGAGTCAGTAACTACAATGGCTACAATCGACAAGAACGCTCAAGCTCTTCTTAATGAATACGGACGTCTTG ATTCAGATTCATTTGAGCGTAACTCTAAGACAGAAGTAATGGCTTCTGCTGTTAAAGATGCTACTAGCTCAATGGATATC AAATTGGTTGTAACTCTTACTAAGACAGGTCATACTGCACGTTTGATTTCTAAATACCGTCCAAATGCTGACATCTTAGC ATTGACATTTGACGAATTGACAGAACGTGGCTTGATGTTGAACTGGGGTGTTATCCCAATGTTGACAGATGCTCCATCTT CAACTGACGATATGTTCGAAATCGCTGAACGTAAAGCGGTAGAAGCAGGTCTCGTTGAGTCAGGCGATGATATCGTTATC GTTGCTGGTGTGCCAGTAGGAGAAGCTGTTCGCACAAACACAATGCGTATCCGCACAGTACGTTAA Protein sequence : MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAKLIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAG KKVGFLLDTKGPEIRTELFEGEAKEYSYKTSEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN GHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATR SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVKDATSSMDI KLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTDAPSSTDDMFEIAERKAVEAGLVESGDDIVI VAGVPVGEAVRTNTMRIRTVR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-80 | 44 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 2e-80 | 44 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 8e-80 | 44 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-80 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pyk | YP_002510826.1 | pyruvate kinase | VFG0479 | Protein | 1e-80 | 44 |
