Gene Information

Name : Hore_04860 (Hore_04860)
Accession : YP_002508239.1
Strain : Halothermothrix orenii H 168
Genome accession: NC_011899
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 525669 - 528281 bp
Length : 2613 bp
Strand : +
Note : PFAM: 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I

DNA sequence :
GTGAAGAAAAAGCTTTATTTGCTGGATGGACAAAGCCTGGCCCACAGGGCTTTTTATGCATTGCCCCTGCTTTCAACTTC
CCGGGGGGAGTATACTAATGCTGTGTTTGGATTTACCAGGATGTTATTAAAACTACTTGACGAGGAAAAACCTGATTTAA
TTGCGGTTGCCTTTGATAAAAAGGCCCCTACCTTCCGACATAAGGAATATAAAGAATACAAGGCTCATCGCAAAAAGATG
CCGGAAGAATTAAAACCACAGCTGTCTTTAATTAAAGAAGTACTTAAATCTTTTAGTATTCCCATTATTGAAATTGAGGG
TTTTGAGGCCGATGATATTATAGGGACAATGGCACGAAAGGGGGAAGAGGAGGGATTTGAGGTCGTTATTGTAACCGGTG
ACCGGGATGCCCTCCAGCTGGTTACAGAAGATGTTTCTGTAATGTATACCAAAAGAGGCATATCAGATATTGTAAGGTAT
GATTTAAATAAGGTAAGGGAAAGGTACGAACTGGAACCTCAACAGCTTATCGATATGAAGGGTTTGATGGGAGATAGTTC
TGACAATATTCCCGGTGTTCCTGGTATCGGTGAAAAGACGGCCATAAAGTTATTAAAGGAGTTTTCTTCACTGGAAGAGA
TCCTTGACAATATTGATAAGGTCTCCGGTAAAAAGCGGAAGGAAAACCTCCAAAAATATGCTGATCAGGCCCGGCTTAGT
AAGAGACTGGGTGAAATAAAGGTTGATGTTCCCCTGGATGTAGAACTTGACGAGTGCCACCTTGGTAAGTTCCATAAAAA
GAACATCAGGGAGTTATTTGAAAGACTTGAGTTTGCCAGTCTATTGAACAGGTTTAAAGAGAAAACGAGTATTAGTATTG
ATGATATCTCTGTAAAAGAACTGGACAGGAAGGGGCTTGAAAATATCTGTGATAAAGCCCGGAATTTGGGAAAATTGGGG
TTAACCTTAAGGCTTAATAATTATACTACCCCTGTCCGGGCTCATGCCAGCCAGGGAATAATTTCCCTGGGGGAAGGAAA
CCTTTACATCTTTACTGATATAAATGAGGCCATAAGTATTTTAAAACCTATTTTGACAGATATTAGTGTTAAGAAATATA
TTTTAAATTCCAAGGAATGTACTGTATTTTTAAAAAAACACGATATCGAGTTAGAAGGGCTTGTTTTTGATCCTTTACTG
GCATATTACCTCCTCAAACCATCGGGTAAACTACCCGGCCTCAGGGACTTACTGGATCAGGAGTTAAGCCTGTCTCTACC
TGAGGACATAAAAGAAGATAATCTGTATCTTGTTTTCATGGATAATATCTTCAAACTGGCTGAGGGTATGGTTCCTAAAC
TTGAGGATATGGAGCTTATAGAATTATTTAATGATATTGAAATACCTTTAATTACAGTTTTAGCAGAACTGGAGTATAAT
GGTATCAAAGTTGATGCTGAATACCTTGAAAGCCTTTCCCGAAAATGGGAAGAAGAACTAAATGGACTGGAGAGTAAAAT
CCATGAGCTTGCCGGTGAAAAGTTCAATATTAATTCACCCAAACAGCTCGGGGGAATTCTCTTTGAAAAACTGGGGCTCC
CGGTGATAAAGAAAACAAAGACTGGTTATTCTACAGGGGCTAAGGTCCTGGAAAAGCTGGAAGATAAACATCCGATAATA
CCCTTGATTTCTGAATACAGGCAGCTTATGAAGTTGAAGTCAACCTATGTTGATGCCCTGCCTCCGATGATTAACCCCGA
TACCGGGCGGCTCCACACCAGTTTTAATCAGATGGTTACTGCAACCGGGAGGTTAAGCAGTACTGAACCCAACCTTCAGA
ATATTCCTGTAAGGACTGATGAGGGTCGAGAAATTAGACGGGCCTTTATTACAGAAAATGAAGACTGGGTCCTTCTGGCA
GCAGATTATTCCCAGATAGAATTGAGGGTACTGGCCCATATCAGTGATGATGAAGGTTTAAAGGCAGCCTTTAACACCGG
TCAGGATATTCATACCCAGACCGCCAGTGAGGTTTTTGAAGTTGAACCTGATGAAGTAACTCCAAATATGAGGCGGCATG
CCAAGGTTATTAACTTCGGTATTGCTTATGGAATGAGCCCGTATGGACTGGCCCGGGACCTGGGTATTTCTAGACAGGAG
GCCAGTGATTATATAAATAAATATTTTGAGAGGTTTACCGGGGTAAAAGATTATATGGAAAGGGTTGTAACTGAGGCCAA
AACTAAAGGTTATGTAACCACTATTTTTAACCGGAGACGGTATATTCCCGAAATTAATAGTCGTAATTACCACCGGCGTT
CATTTGCTGAAAGAACAGCAATAAATACTCCCATTCAGGGTACTGCTGCTGATATTATGAAACTGGCCATGATAAAAGTT
TATAATCGTCTTAAAGAAAATGGCTCCCCGGCCCGGATTTTACTCCAGGTTCATGATGAGCTAATTCTTGAGGTGCCCCG
GGAGGACCTTACTGAAATGGCCCGGATTGTTAAATCAGAGATGGAAAAAGCAGTTGATATGAAAGTCCCACTTGTGGTTA
ACTTGGAGAGTGGTCCCAACTGGCTTAATAAAGAGGAATTAGATATAGAGTAA

Protein sequence :
MKKKLYLLDGQSLAHRAFYALPLLSTSRGEYTNAVFGFTRMLLKLLDEEKPDLIAVAFDKKAPTFRHKEYKEYKAHRKKM
PEELKPQLSLIKEVLKSFSIPIIEIEGFEADDIIGTMARKGEEEGFEVVIVTGDRDALQLVTEDVSVMYTKRGISDIVRY
DLNKVRERYELEPQQLIDMKGLMGDSSDNIPGVPGIGEKTAIKLLKEFSSLEEILDNIDKVSGKKRKENLQKYADQARLS
KRLGEIKVDVPLDVELDECHLGKFHKKNIRELFERLEFASLLNRFKEKTSISIDDISVKELDRKGLENICDKARNLGKLG
LTLRLNNYTTPVRAHASQGIISLGEGNLYIFTDINEAISILKPILTDISVKKYILNSKECTVFLKKHDIELEGLVFDPLL
AYYLLKPSGKLPGLRDLLDQELSLSLPEDIKEDNLYLVFMDNIFKLAEGMVPKLEDMELIELFNDIEIPLITVLAELEYN
GIKVDAEYLESLSRKWEEELNGLESKIHELAGEKFNINSPKQLGGILFEKLGLPVIKKTKTGYSTGAKVLEKLEDKHPII
PLISEYRQLMKLKSTYVDALPPMINPDTGRLHTSFNQMVTATGRLSSTEPNLQNIPVRTDEGREIRRAFITENEDWVLLA
ADYSQIELRVLAHISDDEGLKAAFNTGQDIHTQTASEVFEVEPDEVTPNMRRHAKVINFGIAYGMSPYGLARDLGISRQE
ASDYINKYFERFTGVKDYMERVVTEAKTKGYVTTIFNRRRYIPEINSRNYHRRSFAERTAINTPIQGTAADIMKLAMIKV
YNRLKENGSPARILLQVHDELILEVPREDLTEMARIVKSEMEKAVDMKVPLVVNLESGPNWLNKEELDIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 8e-155 43