Gene Information

Name : Hore_03220 (Hore_03220)
Accession : YP_002508078.1
Strain : Halothermothrix orenii H 168
Genome accession: NC_011899
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 330449 - 332203 bp
Length : 1755 bp
Strand : +
Note : PFAM: PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGAGGAAAACAAAGATTGTGTGTACGATTGGACCTGTTAGTGAAAGCAAAGAAATGCTGAAAAAACTTGCAGAAGCTGG
TATGAATGTAGCCAGGCTTAACTTCTCCCATGGTGACCATGAAGAACATGGAAATCGAATTGATACCATCCGTAAAGTAG
AGGCTGAACTTGGTAAACCAATTGGAATTATGCTGGATACAAAAGGTCCAGAAATCCGTACTGGTATGTTAAAGGATGAT
AAGGTTGAATTAAAAAAGGGAGAAGAGATTATTCTGACTACAGAAGACATAGAAGGCGATGAGAACAGGGTTTCTGTAAG
TTATAAAGGCCTTCCTGATGATCTCCATGAAGGGGCTACTGTTTTAATTGATGATGGATTGATTGGTTTAGAGGTATTGG
AGATTAAGGGTACCGAAATAAGATGTAAAATTGTAAATGGTGGTCTCCTTGGCTCCAGAAAAGGGGTAAATCTTCCTGGA
ATATCTGTAAATTTACCGGCCCTGACCGAAAAAGATGAAAGTGATATTAGATTTGGAGTAAGAAAAGGTATTCATTTTAT
TGCAGCCTCTTTTGTTAGAAAGGCCCAGGATGTTATCGAAATTCGTAAAATACTGGAAGAAGAAGGAAAAGAAGATATAC
TTATTATTGCCAAGATAGAAAACCAGGAAGGTGTCGATAATATTGATGAAATAATTGATGTGGCTGATGGAATTATGGTT
GCCAGGGGTGACCTGGGGGTTGAGATTCCTGCAGAACAGGTACCTGTAATCCAGAAGTCTATCATCAAAAAGTGTAATGA
AAAGGCAAAACCGGTTATTACTGCAACTCAAATGTTGGATTCAATGATAAGAAATCCGAGACCAACAAGGGCCGAAGCTT
CCGATGTGGCCAATGCTATTTTTGACGGCACTGATGCTACTATGCTTTCTGGAGAATCAGCTGCCGGTGATTATCCGGTA
GAAGCAGTAAAGACTATGGCACGTATAGCCGAAGAGACAGAAAAATCCCTTTATTACCGGGATGTAATAAGCAATAGAAG
GACCTATAGACCTCAGACTGTGACCGATGCTATCAGTTTTGCTTCTTGTGAAACTGCAACTGATTTAGGAGCCCAGGCCA
TTATTACATCTACCGAGTCTGGTTTAACAGCCAGGATGGTGTCAAGATACAGGCCATTGGTACCTATTGTTGCTGTTACC
CCTGATGAGAGGGTTCAACATGCCTTAACTGTCAGCTGGGGTGTTTATCCATTAACAGTTAAGAAGAGTAACTCTACTGA
TGAAATGATGGATGTTTCTATAAAGACAGCCCAGGAGAACAGATTAATTAAAAGTGGTGATTTAGTTGTAATTACAGCCG
GTGCCCCAGTAGGTATACCGGGAACTACTAATCTTATTAAAGTTGATGTCGTTGGTGAACCACTGGTTGAAGGTCAGGGT
GTTGGCAAAGGAATTGTAACCGGTCAGGTTAAAATTGCTCATACTGCTAAAGAAGCTGTTGAAAAAATTGAAGAAGGGGA
TATACTGGTAACCGGTATTACCGATAAGGAATATTTACCTGCTATGAAAAAAGCAGGGGCTATAATAGCTGAACAGGGGG
GTCTAACATCACATCCCGCTATTGTGGGGTTAGAACTGGGTATTCCCGTAATAGTAAAGGCTGAAAAGGCTACTGAAAAT
CTTGTAGAAGGAGAAATTATAACTATCGATGGAGTACGGGGCCTGGTTTACCCTGGAACTGTTCATCTAAAATAG

Protein sequence :
MRKTKIVCTIGPVSESKEMLKKLAEAGMNVARLNFSHGDHEEHGNRIDTIRKVEAELGKPIGIMLDTKGPEIRTGMLKDD
KVELKKGEEIILTTEDIEGDENRVSVSYKGLPDDLHEGATVLIDDGLIGLEVLEIKGTEIRCKIVNGGLLGSRKGVNLPG
ISVNLPALTEKDESDIRFGVRKGIHFIAASFVRKAQDVIEIRKILEEEGKEDILIIAKIENQEGVDNIDEIIDVADGIMV
ARGDLGVEIPAEQVPVIQKSIIKKCNEKAKPVITATQMLDSMIRNPRPTRAEASDVANAIFDGTDATMLSGESAAGDYPV
EAVKTMARIAEETEKSLYYRDVISNRRTYRPQTVTDAISFASCETATDLGAQAIITSTESGLTARMVSRYRPLVPIVAVT
PDERVQHALTVSWGVYPLTVKKSNSTDEMMDVSIKTAQENRLIKSGDLVVITAGAPVGIPGTTNLIKVDVVGEPLVEGQG
VGKGIVTGQVKIAHTAKEAVEKIEEGDILVTGITDKEYLPAMKKAGAIIAEQGGLTSHPAIVGLELGIPVIVKAEKATEN
LVEGEIITIDGVRGLVYPGTVHLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-106 53
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-106 53
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-106 53
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-106 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hore_03220 YP_002508078.1 pyruvate kinase VFG0479 Protein 5e-107 53