Gene Information

Name : Hore_16980 (Hore_16980)
Accession : YP_002509442.1
Strain : Halothermothrix orenii H 168
Genome accession: NC_011899
Putative virulence/resistance : Virulence
Product : nucleoside-diphosphate sugar epimerase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 1816782 - 1818245 bp
Length : 1464 bp
Strand : -
Note : PFAM: 3-beta hydroxysteroid dehydrogenase/isomerase family; short chain dehydrogenase; NAD dependent epimerase/dehydratase family; Male sterility protein; Polysaccharide biosynthesis protein; RmlD substrate binding domain

DNA sequence :
ATGAAAAATTTATTAATTATAGGAGCTGGAAGTGCCGGTAAGCTTGTTCTTGAGGAAATTTTAAAAAATAACGAGAGCTA
TAATTATAATATAATTGGTTTTTTAGACGCTGATATTAATAAGCATGGGACAAGCATTCATGGCTATAAAGTTTTAGGTC
ATCATGATAATATTTCCTTTTATATTGATCAATACAGTGTTGATGAAGTTATAGTAGCCACTACAGAAATTGACCGTGCT
GGATTAGAAAAAATATACCAAAACACAAAGAAATTTCAAATTGGGATAAAAGTTTTACCAACCCTTCAAGAGTTACTTAT
GGAAGAACCTTTCACTAAACAATTGAGAGAAGTAAGGGTAGAAGATTTATTAGGTAGAGAGCCTGTAAAAATTAATAGTG
ATAACATCTATAAATATATCAATCATAAAAAGGTGTTGGTTACTGGGGCTGCTGGATCAATAGGAAGTGAACTTTGTCGC
CAGATTGCTAAATATGATCCCCGGGAGTTAATAATATTAGACATAAATGAAAATGAACTCTATTTTTTAAATCTATTTTT
AAAAAGACATTATAATTTAAATGTCAGTTTAGAAATATGTAATATAAGGGAAAAAAGCAAATTAGAATATTTATTTAACT
ATTACAAACCTCAGCTTGTATTCCATGCTGCAGCCCACAAACATGTACCATTAATGGAAAAAAATATAGATGAAGCTATA
AAAAATAATGTTTTTGGTACTAAAAACCTGCTGGATCTTTCTGACAAATATGGAGTGGAAAAGTTCGTTTTAATATCAAC
TGATAAAGCCGTTAATCCTACCAATGTTATGGGGGCTACTAAACGTTTATCAGAAATTATGTTGGAGAAGATCAATAAAT
ATTCTAAAACCCAGTACATGGCAGTAAGATTTGGAAATGTCTTAGGAAGTAATGGCAGTGTGGTACCTTTATTTAAAACT
TTAATTAAAGAGGGTAAAGATTTAACAGTTACCCATGAAGAGGCAACCCGTTACTTTATGACCATACCGGAAGCTGTCCA
ACTTGTCCTTGAAGCTGGTTTTATAGGTAAAGGGGGAGAAGTTTTTGTTCTGGATATGGGTGAACCTGTTAAAATAATAG
ATTTAGCTAAAAAGATGATTGAGTTGTCAGGTTTAACCCTGGGTAGGGATATTAATATAAAAATTACTGGTTTAAGGCCT
GGTGAAAAATTACATGAAGAACTTATGCATGATATTAACTCTTGTGAAAAGACACAGAATAAAAAAATATATATTGCAAA
GATAAGAGAAGAAAATGTAGATATAGAAAAAGGTTTACAGGATTTAAAACGATATTTGATGTCTTTTGACAGAAAAAAAC
TGGTAAAAAAGCTTAAAGAATTGGTACCTACTTATAAAGACAATAGTTATAGTGAGGAGAATATAGATGGAAGACAAACT
AAATATTCCGTTATCAGTACCTAA

Protein sequence :
MKNLLIIGAGSAGKLVLEEILKNNESYNYNIIGFLDADINKHGTSIHGYKVLGHHDNISFYIDQYSVDEVIVATTEIDRA
GLEKIYQNTKKFQIGIKVLPTLQELLMEEPFTKQLREVRVEDLLGREPVKINSDNIYKYINHKKVLVTGAAGSIGSELCR
QIAKYDPRELIILDINENELYFLNLFLKRHYNLNVSLEICNIREKSKLEYLFNYYKPQLVFHAAAHKHVPLMEKNIDEAI
KNNVFGTKNLLDLSDKYGVEKFVLISTDKAVNPTNVMGATKRLSEIMLEKINKYSKTQYMAVRFGNVLGSNGSVVPLFKT
LIKEGKDLTVTHEEATRYFMTIPEAVQLVLEAGFIGKGGEVFVLDMGEPVKIIDLAKKMIELSGLTLGRDINIKITGLRP
GEKLHEELMHDINSCEKTQNKKIYIAKIREENVDIEKGLQDLKRYLMSFDRKKLVKKLKELVPTYKDNSYSEENIDGRQT
KYSVIST

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-71 45
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 2e-68 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hore_16980 YP_002509442.1 nucleoside-diphosphate sugar epimerase VFG1300 Protein 3e-72 45