Gene Information

Name : leuS (Ccel_3454)
Accession : YP_002507722.1
Strain : Clostridium cellulolyticum H10
Genome accession: NC_011898
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 4018870 - 4021314 bp
Length : 2445 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCCATACTCAGCAGATATAGATAGAAAGTGGCAAAAAAAGTGGGAAGAAACAGGTATTTATAGGTTTAACCCTGAAGA
AACCGACAAAAAGCTATACTGTCTGGAGATGTTTTCATACCCATCAGGTGCTAACCTTCATGTGGGACATTGGTACAATT
ACGGTTTGACTGATTCCTGGGCCAGAATGAAAAGAATGCAGGGATATAATGTGTTTCATCCCATGGGCTTCGATGCTTTT
GGGCTTCCCGCAGAAAACTATGCAATAAAAACAGGTATTCATCCACAGGACTCTACACTAAAAAATATTGAGACAATGGA
AGGCCAGCTCAAGGAAATGGGTGCTACCTTTGATTGGGATTATGAGATAAAAACCTGTATGCCCGACTATTACAAATGGA
CACAGTGGCTGTTTCTTCAATTATATAAGTCCGGCCTTGCCTATAGAAAAAATGCACCTGTTAACTGGTGCCCGAAATGC
AACACCGTTCTTGCAAATGAGCAGGTGGTTGACGGGTGCTGTGAAAGATGTGATACAGAGGTAACAAAGCGTGACCTGAC
TCAGTGGTTCTTTAAGATAACCGCTTATGCTCAGGAACTTCTGGATAAGCTTGATACTATTGACTGGCCAGAAAAAACAA
AAAAGATACAAACAAACTGGATAGGACGTTCAGAAGGTGCTGAAATATCCTTCAAAGTTGTTGACACAGATATTGAGTTT
CAGGTATTCACAACAAGAGCCGACACCCTTTATGGTGTAACATATGTTGTTCTGGCTCCTGAAAATCCAATAGTTGAGAA
CATAACAAGACCCGAGTATGCAGAAGCAGTTGAAAAGTATAAAAACGATACTAAAAAGCAGACAGAAATAGAAAGGCTTT
CAACAACAAAAGAAAAGACAGGTGTATTCACCGGCAGTTATGCAATTCACCCAATCACGGGGGAAAAAGTACCTGTATGG
ATTGCGGACTACGTTCTTGCAAGCTATGGAACAGGATGTGTAATGGCTGTTCCGTCACATGATGAACGTGACTTTGAATT
TGCAAAGAAATATAACCTGCCTATTAAGAGGGTTATAAAAAGTGCTGACGGTTCAAATGACGAGCTTCCGTACTGTGAAT
ACGGTGTTCTGGTTAATAGTTCAGAATTTGACGGGGTTCCCTCTACTGAAGCGAGAACCGCTATAATAAAGAAGCTGGAA
GCTGACGGCAAAGGAAGTTTGAAGATAAACTACAGACTGAGAGACTGGCTTGTTTCAAGACAAAGGTACTGGGGTGCCCC
TATCCCTGTAGTTTACTGCGAGCACTGCGGCGAAGTTGCAGTCCCGGAAGAAAACCTCCCTGTTACTCTTCCTTACAATG
TTGAATTTAAACCTGACGGAGAATCCCCTCTTAAAAAGAGTGAGGAATTTATGAATACCGTTTGTCCGAAATGCGGTGCT
ACGGCCAAGAGAGATCCTGATACTCTCGATACATTTGTTTGCTCGTCATGGTACCATCTCAGATATCCTGACAATCGAAA
CAATGATAAGCCCTTTGACACCGAATGGATAAACAAGCTGCTCCCTGTTGACAAGTACGTAGGCGGTGCCGAACATGCAG
CAATGCATCTGCTGTATGCGAGGTTTATAACCAAAGCATTGAGAGATTTGGGCTTCCTCAATTTTGACGAACCGTTCCTG
TCACTTGTACACCAAGGTACAATACTTGCCCCAGATGGGAGTAAAATGAGTAAATCAAGAGGAAACACTATTTCTCCTGA
TGATTACGTGAGAAAGTACGGTTCCGATATATTCAGAATGTACCTTGGTTTCGGTTTCAACTATGTTGATGGCGGACCAT
GGAGTGATGACGGAATAAAAGCTATTTCAAGATTTGCAAGCAGAATAGAAAGGCTTGTTGAAAGTCTAGCAGAGCAAAAA
TCAAAGGCTTCCAGAACTGATATAGACAAGGATGACAAGGAGCTGAACTTTGTCCGTCATACTGCTATAAAAGGTGCCAC
TCAGGATACCGACAGATTCCAGTTCAACACCGCAATTTCCCGCTGTATGGAGCTTGTAAACGCACTTTTCAAGTATGATG
CAGAGGTCAAAACTAAGAATATACAACTATTTGAGGATACTATAAAAGACCTGGTCAAGCTTGTTTCTCCTTTTGCACCT
CACTTTGCAGAAGAAATGTGGGAACAGCTGGGCTGCGAATACTCTTTATTCAACCAGAAATGGCCTGAATTTGACGAAAA
TGCGTTAGTTAAAGACACTATAGAGCTTGCAGTACAGGTTAACGGTACAGTCAGGGGCAAAATAGAGATTGCCGCCGATG
CTGACAACAGTGCAGCGGAAGCTGCTGCCTTGGCTGATGAGAAAATAAAGCCTTTCCTTGATGGAAAAGAGATAAAGAAA
GTAATAGTAGTAAAAGGAAGACTCGTTAATATAGTTGCAAAATAA

Protein sequence :
MPYSADIDRKWQKKWEETGIYRFNPEETDKKLYCLEMFSYPSGANLHVGHWYNYGLTDSWARMKRMQGYNVFHPMGFDAF
GLPAENYAIKTGIHPQDSTLKNIETMEGQLKEMGATFDWDYEIKTCMPDYYKWTQWLFLQLYKSGLAYRKNAPVNWCPKC
NTVLANEQVVDGCCERCDTEVTKRDLTQWFFKITAYAQELLDKLDTIDWPEKTKKIQTNWIGRSEGAEISFKVVDTDIEF
QVFTTRADTLYGVTYVVLAPENPIVENITRPEYAEAVEKYKNDTKKQTEIERLSTTKEKTGVFTGSYAIHPITGEKVPVW
IADYVLASYGTGCVMAVPSHDERDFEFAKKYNLPIKRVIKSADGSNDELPYCEYGVLVNSSEFDGVPSTEARTAIIKKLE
ADGKGSLKINYRLRDWLVSRQRYWGAPIPVVYCEHCGEVAVPEENLPVTLPYNVEFKPDGESPLKKSEEFMNTVCPKCGA
TAKRDPDTLDTFVCSSWYHLRYPDNRNNDKPFDTEWINKLLPVDKYVGGAEHAAMHLLYARFITKALRDLGFLNFDEPFL
SLVHQGTILAPDGSKMSKSRGNTISPDDYVRKYGSDIFRMYLGFGFNYVDGGPWSDDGIKAISRFASRIERLVESLAEQK
SKASRTDIDKDDKELNFVRHTAIKGATQDTDRFQFNTAISRCMELVNALFKYDAEVKTKNIQLFEDTIKDLVKLVSPFAP
HFAEEMWEQLGCEYSLFNQKWPEFDENALVKDTIELAVQVNGTVRGKIEIAADADNSAAEAAALADEKIKPFLDGKEIKK
VIVVKGRLVNIVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-160 44