Gene Information

Name : Ccel_2569 (Ccel_2569)
Accession : YP_002506877.1
Strain : Clostridium cellulolyticum H10
Genome accession: NC_011898
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 3092206 - 3093948 bp
Length : 1743 bp
Strand : -
Note : TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; pyruvate kinase barrel; pyruvate kinase alpha/beta; KEGG: csc:Csac_1831 pyruvate kinase

DNA sequence :
ATGAGAAGAACAAAAATTATTTGTACATTGGGGCCTGCTTCGGATAATGAGGATATATTGAGGAAAATGATGCTTGGTGG
TATGAGTCTGGCAAGAATGAATTTTTCACACGGGACTCATGAAGAACACAAAAAAAGGGCAGACTTAGTAAAGAAAATAA
GAGAAGAACTTAATCTTCCGATACCTTTATTGCTTGATACAAAGGGTCCTGAAATAAGAACAGGTAAATTTAAGAACGAC
CAGGCTATACTAAAGGAAAATAATGAGTTTATACTTGTTAACGAGGATATACTAGGTGATGAAACAAAATGTACAATTAC
CTATAAGGAACTGTACAAGGATGTTTCAAGAGGAAGCAAGATACTTATTAATGACGGTTTGGTTGAGCTTGAGGTTACAG
AGATAAAAAATAAGGATATCTACTGTAGAGTGCTTAACGGCGGTGCAGTGGGAAATCACAAGGGAATAAATGTACCCGGT
GCGGAAATTAAACTTCCTTCATTGACAGAGCAGGACATTGACGATATTAAATTCGGAATAAAGAATGACTTTGATATTAT
AGCGGCTTCATTTGTGAGAAAAGCTTCCGATGTTGTGGAAATAAGGAAGGTTCTTGAGAAGAACGGCGGCAAGGATATAC
TGATAATAGCAAAAATAGAGAACAGGGAAGGTATAAAGAACTTCAATGATATCCTTAAGGTATCTGACGGAATAATGGTA
GCAAGAGGAGACCTGGGAGTGGAAATACCTGTCGAAGAGGTTCCGATTGTTCAGAAAAATATTATAGAGAAATGCTATCA
GAACGGTAAACCGGTTATAACAGCCACTCAAATGCTTGACTCCATGATAAGAAATCCAAGACCTACAAGAGCCGAAGCGA
GTGATGTTGCAAATGCCATTTTCGACGGAACAAGCTGTGTGATGCTTTCAGGAGAAACAGCTGCCGGTAAATATCCCATT
GAAACCATTGAGGTAATGGCAAAAATAGCTGAAAAGGCAGAAAAATCCATGGACTACTGGAATAGATTTGCAACCGCACG
TACAGAATTAGATACCAGTGTAACGAATGCTATCAGTCATGCGACCTGTACCACCGCTCTGGATCTAAAGGCTGCCGCCA
TAATAACGGTTACACAGTCGGGACACACTGCAAGAATGATAGCAAGATTCCGACCTGCATGCCCTATTATTGCAACGACA
GCAAATCCCAAGGTACAAAGGCAGTTAAATTTATCCTGGGGAGTTATGCCATATCTTGTAGGAATTGCAAAAACAACTGA
TGATATGTTTGACAACGGAGTTGAAAAGGCATTGGAATCCGGCCTGGTAAAAAACGGTGACCTTGCAGTAATAACAGCCG
GTATGCCTGCCGGAATAAGCGGAACAACCAATACACTTAAAGTTCATATTGTAGGAAGGGTATTGGTTCAGGGAGTGGGA
ATCGGTACGTCATCTGTTACGGGCGAATTATGTGTTGCCCAGAATACTAAAGAGGCAATGGATAAATTCACCGATGGCAA
TATTATAGTAGCTCCATTCACAGATAACTCCATGCTTCCGGTTATTAAGAGGGCATCCGCCATAGTGGTTGAAGAGCATG
GACAGTCGTGCCATGCTGCAACAGTGGGGCTTGCACTGGATATTCCTGTGATACTGGGGGCTGAAAATGCTACAAAAATA
TTGAAAGCCGGCTCTGTTGTAACAGTTGATTCTGAAAGAGGGCTGGTTATAAGATGTAACTGA

Protein sequence :
MRRTKIICTLGPASDNEDILRKMMLGGMSLARMNFSHGTHEEHKKRADLVKKIREELNLPIPLLLDTKGPEIRTGKFKND
QAILKENNEFILVNEDILGDETKCTITYKELYKDVSRGSKILINDGLVELEVTEIKNKDIYCRVLNGGAVGNHKGINVPG
AEIKLPSLTEQDIDDIKFGIKNDFDIIAASFVRKASDVVEIRKVLEKNGGKDILIIAKIENREGIKNFNDILKVSDGIMV
ARGDLGVEIPVEEVPIVQKNIIEKCYQNGKPVITATQMLDSMIRNPRPTRAEASDVANAIFDGTSCVMLSGETAAGKYPI
ETIEVMAKIAEKAEKSMDYWNRFATARTELDTSVTNAISHATCTTALDLKAAAIITVTQSGHTARMIARFRPACPIIATT
ANPKVQRQLNLSWGVMPYLVGIAKTTDDMFDNGVEKALESGLVKNGDLAVITAGMPAGISGTTNTLKVHIVGRVLVQGVG
IGTSSVTGELCVAQNTKEAMDKFTDGNIIVAPFTDNSMLPVIKRASAIVVEEHGQSCHAATVGLALDIPVILGAENATKI
LKAGSVVTVDSERGLVIRCN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-98 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-97 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-98 48
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-98 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ccel_2569 YP_002506877.1 pyruvate kinase VFG0479 Protein 3e-98 48