Gene Information

Name : guaA (Ccel_2202)
Accession : YP_002506524.1
Strain : Clostridium cellulolyticum H10
Genome accession: NC_011898
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2574335 - 2575870 bp
Length : 1536 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGAACAATGAAATGATATTAGTTCTTGATTTCGGCGGACAGTACAATCAGCTGATAGCACGCCGAGTGAGAGAAGCAAA
TGTTTATTGCGAGGTAATTCCTTATAACGCATCTTTAGAACGTATAAAATCATACAACGCAAAAGGAATAATTTTTACTG
GTGGGCCCAATTCAGTTTTGGATGAGGGAGCACCAAAGTGTGACCCGGGTGTTTTTGAGCTGGGAATACCTGTTCTGGGC
ATATGCTATGGTATGCAGCTCATGAGTGTTATGCTGGGCGGAAGTGTAACTGCTGCTAATCAGCGTGAATATGGAAAGGT
TGAAATTTGTGTAGATAAATCACAGCCTTTGTTCAGGGATGTGGACGAAAATACAATATGCTGGATGAGTCATACCTACT
ATGTTGATACACCTCCTAAGGGTTTTGAAGTAATAGCAAAGTCAGCAAATTGTCCAACAGGTGCAATGCAGCATGTTGAA
AAGAACCTCTATGCGGTCCAGTTCCACCCGGAGGTAATGCATACGCCTAAAGGAAAAGAAATGCTTAAAAACTTCCTATA
CAATATTTGCGGCTGTAAAGGCGACTGGAAGATGTCATCATTTGTTGAAAACTCGATTAATGCAATACGTGAGAAGGTTG
GAGACAAAAAGGTATTGTGTGCACTGTCCGGCGGGGTTGATTCATCTGTGGCGGCAGTACTGATTCATAAGGCTATTGGA
AAGCAGCTGACTTGTATATTTGTTGACCATGGACTTTTGAGAAAATATGAGGGAGACCAGGTTGAGCAGATTTTCAGAAA
GCAGTATGATATCAACCTGATTCGTGTAAATTGTGAAGACAGATTTTTGCAGAGACTTAAAGGCGTTTCTGATCCCGAAA
CCAAAAGAAAAATTATTGGTGAAGAATTTATAAGAGTATTTGAAGATGAGGCAAAGAAAATTGGAAAGGTTGATTTCCTT
GTTCAGGGAACAATTTATCCTGATGTCATTGAAAGCGGAATCGGTGATGCAGCCGTTATAAAGAGCCATCATAATGTTGG
AGGTCTGCCAGAACATGTTGATTTTAAGGAGATTATCGAACCTCTCAGAAGCCTTTTCAAGGACGAAGTAAGAAGGGCGG
GAGAGGAATTGGGTATTCCTGAAGACTTGGTTTGGAGACAGCCATTCCCGGGCCCCGGACTTGCTATAAGGGTTATCGGT
GATTTGACAAAAGAAAAGCTGGACACTCTAAGAGATACCGACTACATTTTCCGTGAAGAAATCAAGGCTGCCGGATTGGA
CAAAGAGATTAACCAGTATTTCACAGTTTTGACAAATATGCGAAGTGTAGGCGTGATGGGTGACGAAAGAACTTATGACT
ACGCCTTGGCACTGCGTGCGGTAACGACCACCGACTTTATGACAGCCGACTGGGCAAGAATCCCATACGATATTCTGGAG
AAGGTCTCCACTCGTATTGTCAACGAAGTCAAGCAAATCAACAGAATTGTGTATGATATCACCTCGAAGCCACCAGCTAC
GATTGAGTGGGAATAA

Protein sequence :
MNNEMILVLDFGGQYNQLIARRVREANVYCEVIPYNASLERIKSYNAKGIIFTGGPNSVLDEGAPKCDPGVFELGIPVLG
ICYGMQLMSVMLGGSVTAANQREYGKVEICVDKSQPLFRDVDENTICWMSHTYYVDTPPKGFEVIAKSANCPTGAMQHVE
KNLYAVQFHPEVMHTPKGKEMLKNFLYNICGCKGDWKMSSFVENSINAIREKVGDKKVLCALSGGVDSSVAAVLIHKAIG
KQLTCIFVDHGLLRKYEGDQVEQIFRKQYDINLIRVNCEDRFLQRLKGVSDPETKRKIIGEEFIRVFEDEAKKIGKVDFL
VQGTIYPDVIESGIGDAAVIKSHHNVGGLPEHVDFKEIIEPLRSLFKDEVRRAGEELGIPEDLVWRQPFPGPGLAIRVIG
DLTKEKLDTLRDTDYIFREEIKAAGLDKEINQYFTVLTNMRSVGVMGDERTYDYALALRAVTTTDFMTADWARIPYDILE
KVSTRIVNEVKQINRIVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-155 61
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-155 61
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-155 61
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-136 54