Gene Information

Name : Ccel_1310 (Ccel_1310)
Accession : YP_002505644.1
Strain : Clostridium cellulolyticum H10
Genome accession: NC_011898
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase subunit
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : -
Position : 1615000 - 1615485 bp
Length : 486 bp
Strand : +
Note : PFAM: dihydrofolate reductase region; KEGG: gtn:GTNG_1670 dihydrofolate reductase

DNA sequence :
ATGATTTCAATGATATGGGCTATGGGCCGCAACAACGCCCTTGGATGTAAAAACAGAATGCCCTGGTACATTCCCGCAGA
TTTTGCATATTTCAAAAAAGTTACAATGGGAAAACCGGTCATTATGGGGAGAAAAACTTTTGAATCTATCGGTAAACCTT
TACCGGGCAGAAAGAACATAGTAATTACTCGAGACACAGGATATGATCCACAAGGCTGTATTGTGGTTAATTCTATAGAA
AAAGCCATGGAGTATACAGAAGAAAAGGAAGTCTTTATAATAGGGGGAGCAGAAATATACAAAGAATTTCTTCCTATTGC
AGACAGACTATATATAACTCTGATAGAAAAAGAGTTTGAAGCGGATGCATTTTTCCCGGAAATAGACTATAGTAAGTGGA
AGCAGATATCCTGCGAAACAGGAATCAAGGATGAAAAAAATCCATATGAGTATAAGTGGTTGGTATACGAAAGAGTTAAA
CAATAA

Protein sequence :
MISMIWAMGRNNALGCKNRMPWYIPADFAYFKKVTMGKPVIMGRKTFESIGKPLPGRKNIVITRDTGYDPQGCIVVNSIE
KAMEYTEEKEVFIIGGAEIYKEFLPIADRLYITLIEKEFEADAFFPEIDYSKWKQISCETGIKDEKNPYEYKWLVYERVK
Q

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA5 AET25387.1 dihydrofolate reductase Not tested PAGI-2(C) Protein 1e-14 43
dfrA5 AFG30110.1 dihydrofolate reductase Not tested PAGI-2 Protein 1e-14 43
dfrA1 ADZ05803.1 trimethoprim-insensitive dihydrofolate reductase Not tested AbaR3 Protein 6e-15 42
unnamed AEL12695.1 DfrA5 Not tested AbaR21 Protein 6e-15 42
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 6e-27 41