Gene Information

Name : trpE (MLBr_01269)
Accession : YP_002503544.1
Strain : Mycobacterium leprae Br4923
Genome accession: NC_011896
Putative virulence/resistance : Unknown
Product : anthranilate synthase component I
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 1512163 - 1513752 bp
Length : 1590 bp
Strand : +
Note : with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine

DNA sequence :
GTGCACGCCCACCTCGCCGCCACCACGTCACGTGAGGACTTTCGCCAGCTAGCTGTCGATCATCGGGTGGTTCCAGTGAC
CCGCAAAGTCTTGGCCGATAGCGAAACGCCGCTATCGGCATACCGGAAGCTCGCCGCCAATCGTCCGAGCACCTTCCTGC
TAGAGTCGGCCGAGAACGGCAGATCCTGGTCGCAGTGGTCGTTCATTGGCGTGGGTGCCCCATCGGCTTTGACAATTCGT
GACGGCGAAGCGGTGTGGCTGGGCACTGTACCGCAGGACGCGCCCACTGGCGGTGACCCCCTGCATGTCCTGCAGGCCAC
GCTCGAGCTACTTGCCACCGCGGCAATGCCCGGGTTGCCACCGCTATCGAGTGGTATGGTGGGCTTCTTCGCCTACGACA
TGGTGCGGCGCCTGGAGCGCCTGCCTGAACTGGCCTTAAATGATTTGCAGTTGCCCGATATGCTGCTGCTGTTGGCCACC
GATGTAGCGGCCGTTGACCACCACGAGGGCACGATCACCCTGATTGCCAACGCTGTGAACTGGAACGGTACCGATGAGCG
GGTAGATCAGGCCTACGACGATGCGATCGCGCGCTTGGACGTAATGACCGCAGCACTGGGCCAGCCGCTGCCATCGACCA
TTGCCACGTTCAGCCGGCCCGACCCTCGGCGCCGAGCGCAATGCACCATCGAGGAATACGGTGCGATCGTCGACCACCTC
GTCGACCAGATCGCGGCCGGTGAGGCCTTTCAAGTGGTGCCCTCGCAGCGCTTCGAGGTGGATACCGATGTCGATCCGAT
CGATGTCTATCGCATGCTGCGGGTCACCAACCCTAGCCCTTACATGTATCTGCTGCATGTGCCTAATAGCGATGGAGCAA
CTGGCTTTTCGATCGTTGGATCCAGCCCGGAGGCGTTGGTGACCGTCAAGGACGGTCGGGTGACGACGCATCCGATCGCT
GGAACTCGCTGGCGAGGCCAGACCGAAGAAGAGGATCAGCTACTGGAAAAAGAGTTGCTCGCCGACGAGAAGGAACGAGC
AGAGCACTTAATGCTTGTCGATCTCGGTCGCAACGACCTTGGTCGGGTCTGTACGCCAGGCACCGTACGTGTCGAGGATT
ACAGCCACGTTGAACGTTACAGTCACGTAATGCACATGGTGTCTACGGTGACCGGGCTGCTCGGTGAAGGCCGCACCGCC
CTGGACGCGGTGACCGCCTGCTTCCCTGCCGGCACGCTGTCGGGTGCCCCGAAGGTGCGGTCCATGGAGCTAATCGAGGA
AGTGGAGAAGACGCGCCGCGGCCTTTATGGTGGCGTGGTCGGTTACCTCGACTTCGCTGGTAACGCTGACTTCGCGATAG
CAATCCGTACAGCGCTGATGCGTGACGGCATCGCGTATGTCCAAGCCGGCGGTGGGGTAGTGGCCGACTCCAACGGGCCC
TACGAATACATCGAGGCGAGTAACAAGGCTCGAGCGGTGTTGAACGCGATCGCCGCCGCCGAGACGTTGACCTCTTTGGA
CTTCGGTGTTGCCCTCGCCCCTGGCCGCGTGGCGGCCAGGGGCGAGGCGGGCAATCAAGGGAGGCTGTGA

Protein sequence :
MHAHLAATTSREDFRQLAVDHRVVPVTRKVLADSETPLSAYRKLAANRPSTFLLESAENGRSWSQWSFIGVGAPSALTIR
DGEAVWLGTVPQDAPTGGDPLHVLQATLELLATAAMPGLPPLSSGMVGFFAYDMVRRLERLPELALNDLQLPDMLLLLAT
DVAAVDHHEGTITLIANAVNWNGTDERVDQAYDDAIARLDVMTAALGQPLPSTIATFSRPDPRRRAQCTIEEYGAIVDHL
VDQIAAGEAFQVVPSQRFEVDTDVDPIDVYRMLRVTNPSPYMYLLHVPNSDGATGFSIVGSSPEALVTVKDGRVTTHPIA
GTRWRGQTEEEDQLLEKELLADEKERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHVERYSHVMHMVSTVTGLLGEGRTA
LDAVTACFPAGTLSGAPKVRSMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRDGIAYVQAGGGVVADSNGP
YEYIEASNKARAVLNAIAAAETLTSLDFGVALAPGRVAARGEAGNQGRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00342 YP_008211668.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR26 Protein 1e-65 43
BJAB07104_00338 YP_008207803.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR25 Protein 1e-65 43