Gene Information

Name : Mnod_5381 (Mnod_5381)
Accession : YP_002500529.1
Strain : Methylobacterium nodulans ORS 2060
Genome accession: NC_011894
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 5464832 - 5467468 bp
Length : 2637 bp
Strand : -
Note : KEGG: met:M446_5085 ATP-dependent chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase

DNA sequence :
ATGAACTTCGAAAAATACACCGAGCGCGCCCGCGGCTTCGTGCAGGCCGCCCAGGCCCTGGCGCTCCGCGAAGGCCACCC
GCAGCTCGCGCCGGGTCACGTCCTGAAGGTCCTGCTCGACGATCCGGAGGGCCTCTGCGCCGGCCTGATCGACCGCGCCG
GCGGCCAGTCCCGCGTCGCGCTCGCCCAGATCGAGGCGTGGCTCGCCAAGCAGCCGAAGGTCTCCGGCGCTGCCGCGCAG
CCGCAGGCGACGCGCGACCTCATGCGCCTGTTCGACACGGCCGAGAAGGCCGCCGAGAAGGCGGGTGATTCCTACGTCAC
CGTCGAGCGCCTGCTGCTCGCACTCGCCGTCGAGAAGGACAGCGAGGCCGGCAAGGCCCTCTCCGCCGCGGGCGTGACCG
CCGCCTCTCTCAACGCCGCCATCAACGCCCTGCGCAAGGGGCGCACCGCCGACAACGCCACCGCCGAGAACGCCTACGAC
GCGCTCAAGAAATACGCCCGCGACCTCACTGAGGACGCCCGCGAGGGCAGGCTCGACCCGGTCATCGGCCGCGACGAGGA
GATCCGCCGCACCATCCAGGTCCTGTCCCGGCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGA
CCGCCATCGTCGAGGGGCTGGCGCTGCGCATCGTCAACGGCGACGTGCCCGAATCCTTGCGCGACAAGCGGCTGCTCGCC
CTCGACATGGGCGCGCTGATCGCGGGTGCGAAGTACCGCGGCGAGTTCGAGGAGCGCCTGAAGGGCGTGCTCTCCGAGGT
CACGGCGGCCGAGGGCGGCATCATCCTGTTCATCGACGAGATGCACACGCTGGTCGGCGCCGGCAAGGCGGACGGGGCGA
TGGACGCCTCGAACCTGCTCAAGCCTGCCCTTGCCCGCGGCGAGCTGCATTGCGTGGGCGCGACGACCCTCGACGAGTAC
CGCAAGCATGTGGAGAAGGATGCGGCGCTCGCCCGGCGCTTCCAGCCGGTCTTCGTGTCCGAGCCGAGTGTGGAGGACAC
GGTCTCAATCCTGCGCGGCATCAAGGAGAAGTACGAGCAGCACCACGGCGTGCGCATCCAGGATGCGGCGCTGGTGGCGG
CCGCGACCCTGTCGAACCGCTACATCACCGACCGCTTCCTGCCCGACAAGGCGATCGACCTCGTCGACGAGGCGGCCTCG
CGCCTGCGCATGCAGGTCGATTCCAAGCCCGAGGAACTCGACAACATCGACCGCGAGATCGTGCGGCTGAAGATCGAGGC
CGAGGCGCTCAAGAAGGAGACCGACGCGGCCTCGCGCGACCGGCTGACCCGCCTGGAGAAGGAGCTCGGTGACCTGGAGG
AGCAGTCGTCGGCGATCACGGCGCGCTGGAAGGCCGAGAAGGACAAGCTCGGCCGCGCCGCGGAGCTGAAGAAGAAGCTC
GACGAGGCGCGCACTGAACTCGCCTCCGCGCAGCGGCAGGGCCAGTACCAGCGGGCGGGCGAGCTCGCCTACGGCATCAT
CCCGGGGCTGGAGCGGGAGCTCGCCGAGATCGAGGCGCGCAGCGCCGACGGCACGCGCGGCAACGGCTCGGGCCTGATGG
AAGAGGCGGTGACGCCCAACCACGTGGCGAGCGTCGTCTCGCGCTGGACGGGTGTGCCTGTCGACAAGATGCTGGAGGGC
GAGCGCGAGAAGCTGCTCGCGATGGAGGAGGCCCTGAGCAAACGGGTCGTCGGCCAGCGTGAGGCGGTGGAGGCGGTCGC
GACCGCGGTGCGCCGGGCGCGCGCCGGCCTGCAGGATCCGAACCGGCCGATCGGCTCGTTCATGTTCCTGGGGCCGACCG
GCGTCGGCAAGACCGAGCTGACGAAGGCTCTCGCGAACTTCCTGTTCGACGACGAGACCGCGATGGTGCGCCTCGACATG
TCCGAGTACATGGAGAAGCACTCCGTCGCCCGGCTCATCGGCGCGCCGCCCGGCTATGTCGGCTACGAGGAGGGCGGGGC
CCTCACCGAAGCCGTGCGGCGCCGGCCCTACCAGGTTGTCCTGTTCGACGAGATCGAGAAGGCGCATCCGGACGTGTTCA
ACGTCCTGCTGCAGGTTCTGGACGACGGGCGGCTCACGGACGGCCAGGGGCGGACGGTGGATTTCCGCAATACGCTCCTT
GTGATGACCTCGAATCTCGGCGCCGAGTACCTGGTGACCCAACCGGAAGGCCAGGACACCGATGCGGTCCGCGACGAGGT
GATGGCGGTGGTGCGCGGGCATTTCCGTCCCGAGTTCCTGAACCGCGTCGACGAGATCATCCTGTTCCACCGCCTCAAGC
GGGCGGAGATGGGGGCGATCGTCGATATCCAGCTCGGCCGGCTGCAGAAGCTGCTCGACGAGCGCAAGATCACGCTCGAG
GTCGAGCCGGATGCCCGCGCCTGGCTCGCCGAGCGCGGCTACGACCCGGCCTACGGGGCGCGTCCGCTGAAGCGGGTCAT
CCAGAAGGCGGTGCAGGATCCGCTGGCCGAGCAGCTGCTCGCGGGCGCGATCCACGACGGCGAGACCGTGCCGGTGCGCC
ACGGACCGGAGGGCCTGATCATCGGCGACGTCGCGGTGACGGCCGAACGCCGCCCGGCGAATGTCAGGCTGAACTGA

Protein sequence :
MNFEKYTERARGFVQAAQALALREGHPQLAPGHVLKVLLDDPEGLCAGLIDRAGGQSRVALAQIEAWLAKQPKVSGAAAQ
PQATRDLMRLFDTAEKAAEKAGDSYVTVERLLLALAVEKDSEAGKALSAAGVTAASLNAAINALRKGRTADNATAENAYD
ALKKYARDLTEDAREGRLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPESLRDKRLLA
LDMGALIAGAKYRGEFEERLKGVLSEVTAAEGGIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDAALARRFQPVFVSEPSVEDTVSILRGIKEKYEQHHGVRIQDAALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMQVDSKPEELDNIDREIVRLKIEAEALKKETDAASRDRLTRLEKELGDLEEQSSAITARWKAEKDKLGRAAELKKKL
DEARTELASAQRQGQYQRAGELAYGIIPGLERELAEIEARSADGTRGNGSGLMEEAVTPNHVASVVSRWTGVPVDKMLEG
EREKLLAMEEALSKRVVGQREAVEAVATAVRRARAGLQDPNRPIGSFMFLGPTGVGKTELTKALANFLFDDETAMVRLDM
SEYMEKHSVARLIGAPPGYVGYEEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLL
VMTSNLGAEYLVTQPEGQDTDAVRDEVMAVVRGHFRPEFLNRVDEIILFHRLKRAEMGAIVDIQLGRLQKLLDERKITLE
VEPDARAWLAERGYDPAYGARPLKRVIQKAVQDPLAEQLLAGAIHDGETVPVRHGPEGLIIGDVAVTAERRPANVRLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-107 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-108 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-108 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mnod_5381 YP_002500529.1 ATP-dependent chaperone ClpB VFG2076 Protein 5e-118 42