Gene Information

Name : Mnod_4530 (Mnod_4530)
Accession : YP_002499701.1
Strain : Methylobacterium nodulans ORS 2060
Genome accession: NC_011894
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4584440 - 4586323 bp
Length : 1884 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCCCCCGTCATCCCCCCCAAAGGCCTGCCGCAGAGTGTGACCACCGGGCCGATCGCCGGCTCCGTGAAGGTCTA
TGCCAGTCCCGAGGGGCGGCCTGACATCCGGGTGCCCCTGCGCGAGATCGGCTTGAGCGATCCTTCCGAAGCGCCGGTGC
GTGTCTACGATCCCTCCGGCCCCTACACGGAGAACGAGGCCAAGGTCGACCTCGCGGCCGGGCTGCCGGAGCTGCGCGCG
CCCTGGATCGCGTCCCGCGGCTACGCCGCCGTGACGCCCCGCGCCGTCAAGCCGGAGGATAACGGCTTCGTGGGCGAGGA
TCGGCTGGTCGCCCCCTGTCCGGCGAAGCGCACCATCCGCAAGGCGGCGCCGGGCCAGATGACGACCCAGTACGAGTTCG
CCCGGGCCGGGATCATCACCGAGGAGATGATCTACGTCGCGCACCGAGAGAATCTCGGCCGCAAGGCGATGCTGGAGCAG
GCCGAGGCCAAGCTCGCGGATGGCGAGAGCTTCGGCGCGGCGATCCCGCCCTTCATCACGCCGGAATTCGTGCGCGACGA
GGTCGCCCGCGGGCGCGCCATCATCCCGGCCAACATCAACCACACCGAACTCGAGCCGATGGCCATCGGCCGCAACTTCC
TGGTCAAGATCAACGCCAATATCGGCAACTCGGCCGTGACCTCGTCGGCTGCCGAGGAGGTCGAGAAGATGGTCTGGGCG
ATCCGCTGGGGCGCCGACACCGTCATGGACCTCTCGACCGGCCGCAACATCCACAACATCCGCGGCTGGATCCTGCGCAA
CGCGCCGGTGCCGATCGGGACCGTGCCGATCTACCAGGCGCTGGAGAAGGTCGGGGGCGATCCCCTCAAGCTCGACTGGG
AGGTGTTCAAGGACACGCTCATCGAGCAGGCCGAGCAGGGCGTCGACTACTTCACCATCCATGCCGGCGTGCGCCTCGCC
CATGTGCCGCTCACCGCACGGCGCGTCACCGGCATCGTCTCGCGCGGCGGCTCAATCATGGCGCGCTGGTGCCTCGCCGG
GCACCGGGAATCGTTCCTCTACGAGCGGTTCGACGAGATCTGCGACATCATGCGGGCCTACGATGTCTCGTTCTCGCTCG
GCGACGGGCTGCGCCCCGGCTCGATCGCGGATGCCAACGACGCGGCGCAGTTCGCGGAGCTGGAGACCCTGGGCGAACTC
ACCCGGGTGGCCTGGGACAAGGGCTGCCAAGTGATGATCGAGGGCCCCGGCCACGTGCCGATGCACAAGATCAAGGTCAA
CATGGAGAAGCAGCTGCGCGAGTGCGGCGAGGCGCCGTTCTACACGCTCGGGCCGCTGACCACCGATGTCGCGCCCGGCT
ACGACCACATCACCTCGGGCATCGGGGCGGCGATGATCGGCTGGTTCGGCACCGCAATGCTCTGCTACGTGACGCCCAAG
GAGCATCTCGGCCTGCCGAACCGCGACGACGTGAAGACCGGCGTCATCACCTACAAGATCGCCGCCCACGCTGCCGACCT
CGCCAAGGGCCACCCGGCCGCGCAGCTGCGCGACGACGCCCTTTCCCGCGCCCGGTTCGACTTCCGCTGGGAGGACCAGT
TCAACCTCTCGCTCGATCCCGACACCGCGCGCGCCTATCACGACGAGACGCTGCCGAAGGATGCCCACAAGGTCGCGCAT
TTCTGCTCGATGTGCGGCCCGAAATTCTGCTCGATGAAGATCACGCAGGATCTGCGCGCCGACGTCCTCGCCATGGAGGC
GGCCGGGACGGTGGTGGGCGCCGCGCCGGCGATGAGCGAGGAGGACCGGGCCGCCGGCATGGCGGCGAAATCGGCCGAGT
TCCTGGCTGAGGGCGGCAAGCTCTACGTCGACGCCGCGGAGTAG

Protein sequence :
MNAPVIPPKGLPQSVTTGPIAGSVKVYASPEGRPDIRVPLREIGLSDPSEAPVRVYDPSGPYTENEAKVDLAAGLPELRA
PWIASRGYAAVTPRAVKPEDNGFVGEDRLVAPCPAKRTIRKAAPGQMTTQYEFARAGIITEEMIYVAHRENLGRKAMLEQ
AEAKLADGESFGAAIPPFITPEFVRDEVARGRAIIPANINHTELEPMAIGRNFLVKINANIGNSAVTSSAAEEVEKMVWA
IRWGADTVMDLSTGRNIHNIRGWILRNAPVPIGTVPIYQALEKVGGDPLKLDWEVFKDTLIEQAEQGVDYFTIHAGVRLA
HVPLTARRVTGIVSRGGSIMARWCLAGHRESFLYERFDEICDIMRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGEL
TRVAWDKGCQVMIEGPGHVPMHKIKVNMEKQLRECGEAPFYTLGPLTTDVAPGYDHITSGIGAAMIGWFGTAMLCYVTPK
EHLGLPNRDDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFDFRWEDQFNLSLDPDTARAYHDETLPKDAHKVAH
FCSMCGPKFCSMKITQDLRADVLAMEAAGTVVGAAPAMSEEDRAAGMAAKSAEFLAEGGKLYVDAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 64
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 62