Gene Information

Name : Mnod_3067 (Mnod_3067)
Accession : YP_002498311.1
Strain : Methylobacterium nodulans ORS 2060
Genome accession: NC_011894
Putative virulence/resistance : Resistance
Product : O-succinylhomoserine (thiol)-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3166683 - 3167840 bp
Length : 1158 bp
Strand : +
Note : TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: met:M446_3453 O-succinylhomoserine (thiol)-lyase

DNA sequence : 
GTGGCACATCGGAAGGCCGCACAGACGATCGCCGCCGCGAACGGCATTGGCTCGGATACTGCCTATGGGGCCGTCAGCCC
GCCGCTCTACCTCTCGACGACCTACGCGTTCGAGGGCTTCGAGCGCCCGCGGGCGCACGACTATTCGCGGCTCGGCAACC
CGACCCGCGACCAGCTCGCCGACACCATCGCCAAGCTGGAGGGCGGCGCGCACGCCGTGGTGGTGGCGAGCGGCATGGCG
GCCCTGGACCTCGCGCTCTCGCCCGTTGCGCCCGGCGACCTGCTGGTCGCCCCGCACGACTGCTACGGGGGCACCCACCG
CCTCCTGAGCCAGCGCAGCGCGAAGGGGCACTACCGCGTCGCCTTCGTGGACCAGACCGACGAGAACGCTCTCGCGGCCG
CCCTGGTGGAGCGGCCCCGCCTCGTCCTGATCGAGACGCCGAGCAACCCGCTGATGCGGATTGTGGACATCCGCCGCGTG
GCCGCGCGGGCCAAGGCCGTCGGCGCCCTGCTCGTCGTCGACAACACGTTCCTGTCTCCCGCCCTGCAACAGCCGATCTC
GCTCGGGGCGGACCTCGTCGTCCACTCCACCACGAAATTCCTCAACGGCCATTCGGACGTGATCGGCGGGGCGGTAGTGG
CCGCGGATGCTAAGCTTGGCGAGGATCTTGCCGCCTGGGCGAACACCATCGGCGTCACCGGCTCGCCCTTCGACGCCTAC
CTGACTCTGCGTGGCATTCGCACGCTGTTCGCGCGCGTGGAGCGCCAGCAGCAGAGCGCAGCGGCCATCGCGGCATTCCT
GGCGGCGCACCCGGCGGTGGCGCGCGTCCACTACCCTGGTTTGCCCGAGCACCCGGGACACGCGATCGCGAAGGCGCAGC
AGAGCGGCTTCGGCGCGATGCTGAGCTTCGAACTCGCGGGCGGGCGCGAGGCCATCCGCGCCGTTGTCGAGCGGCTGCGG
GTCTTCACCCTGGCGGAATCGCTTGGCGGGATCGAGAGCCTGATCGCTCACCCGGTGAGCATGACTCACGCGGCCATGGA
TCCCGAGGCGCGCCGGAGGGCCGGCGTGGGCGATGGCCTCTTGCGGCTGTCGGTCGGGCTTGAGGCCGAGGAGGACCTGC
TGGACGACCTCGCGCAGGCCCTCGACGCCGCGCGCTGA

Protein sequence : 
MAHRKAAQTIAAANGIGSDTAYGAVSPPLYLSTTYAFEGFERPRAHDYSRLGNPTRDQLADTIAKLEGGAHAVVVASGMA
ALDLALSPVAPGDLLVAPHDCYGGTHRLLSQRSAKGHYRVAFVDQTDENALAAALVERPRLVLIETPSNPLMRIVDIRRV
AARAKAVGALLVVDNTFLSPALQQPISLGADLVVHSTTKFLNGHSDVIGGAVVAADAKLGEDLAAWANTIGVTGSPFDAY
LTLRGIRTLFARVERQQQSAAAIAAFLAAHPAVARVHYPGLPEHPGHAIAKAQQSGFGAMLSFELAGGREAIRAVVERLR
VFTLAESLGGIESLIAHPVSMTHAAMDPEARRRAGVGDGLLRLSVGLEAEEDLLDDLAQALDAAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-41 41
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-42 41
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-40 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mnod_3067 YP_002498311.1 O-succinylhomoserine (thiol)-lyase BAC0207 Protein 1e-37 42