Gene Information

Name : smpB (Mnod_1485)
Accession : YP_002496780.1
Strain : Methylobacterium nodulans ORS 2060
Genome accession: NC_011894
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1568706 - 1569179 bp
Length : 474 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCCCGCAAACCGGATCCCGGCCGCCGCATCGTTGCGGACAATCGCAAGGCCCGCTTCAACTACGAGATCACCGACAC
GGTGGAGGCGGGCATCGCGCTCACCGGCACCGAGGTGAAGTCGCTGCGCGGCGGCAAGGCGACGATCGGGGAGGCCTATG
CGGGCCCCTCGGGCGACGAGTTCTTCCTGTTCAACGCCTACATCCCCGAATACCTCGAGGCCAACCGCTTCAATCACGAG
ACCAAGCGACCCCGCCGCCTGCTGCTGCACCGGCGCCAGATCAACAAGTTCCTGGGCGCCACCCAGCGCGAGGGCTACAC
GGTCATTCCGCTCAAGATCTATTTCAACGAGCGTGGCCGGGCGAAGGTCGAACTCGGCCTCGGGCGGGGCAAGAAGCTGC
ACGACAAGCGCGAGACCGCCAAGGAGCGCGACTGGCAGCGCGACCGCGCGCGGCTCCTGCGCGACAAGGGGTGA

Protein sequence :
MARKPDPGRRIVADNRKARFNYEITDTVEAGIALTGTEVKSLRGGKATIGEAYAGPSGDEFFLFNAYIPEYLEANRFNHE
TKRPRRLLLHRRQINKFLGATQREGYTVIPLKIYFNERGRAKVELGLGRGKKLHDKRETAKERDWQRDRARLLRDKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 7e-29 49
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 5e-25 47
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 2e-24 41