Gene Information

Name : A2cp1_0414 (A2cp1_0414)
Accession : YP_002490837.1
Strain : Anaeromyxobacter dehalogenans 2CP-1
Genome accession: NC_011891
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 466526 - 469138 bp
Length : 2613 bp
Strand : -
Note : KEGG: ank:AnaeK_0413 ATP-dependent chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase

DNA sequence :
ATGCGAATGGAAAAGCTCACCGTGAAGGCGCAGGAGGTCCTCGCCGCCGCGCAGGGGGAGGCGCGCCGACGCGACCACCA
GGCCGTGGACGTCGAGCACCTCGTGCTCGCGCTGCTCGCGCAGGAGGAGGGCATCGCGCGCCCGGTGCTGGAGAAGATCG
GCGCGGACCCGCGCCTGGTCGCCTCGCGGGTGGAGGACGAGCTGCGCTCGCTGCCGAAGGTGTCGGGCGCGGAGCCCTAC
CCGGCGAACCGGCTGCTGAAGCTGTTCGACCGGGCCGAGGACGAGGCGCGCAAGCTGAAGGACGAGTACGTCTCGACCGA
GCACCTGCTGCTCGCCGCCGCCGAGGACAAGGGCGGCGCCGGCGAGGCGCTGCGCGCGTCCGGCGCGACGCCCGAGCGCG
TCCGCCAGGCGGTGCAGGAGGTGCGGGGCGGCGCGCGCGTCACCTCGCCCGAGGCCGAGAGCCAGTACCGCGCGCTCGAG
AAGTACGCGAAGGACCTCACCGACCTCGCCAGGAAGGGCAAGCTCGACCCGGTCATCGGCCGCGACGACGAGATCCGGCG
CGTGGTCCAGATCCTGTCGCGCCGCACCAAGAACAACCCGGTGCTGGTGGGCGACCCCGGCGTGGGCAAGACCGCCATCG
TGGAGGGGCTGGCGCGCCGCATCGTGGACGGCGACGTGCCGGAGGGGCTGAAGAACAAGCGGCTGCTCGCGCTCGATCTC
GGCGCCCTGCTCGCCGGCGCGAAGTTCCGCGGCGAGTTCGAGGAGCGGCTGAAGGCGGTGCTGAAGGAGGTGACCGGCTC
GGAGGGCCAGATCATCCTCTTCATCGACGAGATGCACACCATCGTGGGCGCCGGCGCCGCCGAGGGCGCCATGGACGCGG
GCAACATGCTGAAGCCCGCGCTCGCCCGCGGCGAGCTGCACGCGGTGGGCGCCACCACCGTGAACGAGTACCGCAAGCAC
ATCGAGAAGGACCCCGCCCTGGAGCGGCGCTTCCAGCCGGTGTTCGTGGGCGAGCCGTCGCTCACCGACACCATCTCGAT
CCTGCGCGGCCTGAAGGATCGCTACGAGCTGCACCACAAGGTCCGCATCCAGGACGCGGCGCTGGTGGAGGCGGCGCGCC
TGTCGAGCCGCTACATCACCGATCGCTTCCTGCCCGACAAGGCCATCGACCTCGTGGACGAGGCGGCCAGCCGGCTGCGC
ATCGAGATCGACTCGATGCCGACCGAGGTGGACGAGGTGCGCCGGCGCATCGGGCAGCTCGAGATCGAGCGGCAGGGCCT
GCGCAAGGAGCAGGACGAGGCCTCCCGCGCGCGGCTCGCCGCGGTGGAGAAGGAGCTCGCCGCCCGCAACGAGGAGTTCA
CCGCGCTGAAGGGGCGCTGGGACGCCGAGAAGGCGGTGATCCAGGAGCTGAGCCAGGCGCGCCAGGAGCTGGAGGCGCTC
AAGGTCGAGCAGGCCGCGGCCGAGCGGCAGGCCGACTTCCAGAAGGCCGCCGAGATCAAGTTCGGCCGGCTGCCGGAGCT
GACGCGGCGGGTGAAGGCCGCCGAGGAGAAGCTCGCCGAGGCCCAGACCCGCGGCGCCATGCTGAAGGAGGAGGTCACGC
CGGAGGAGATCGGCGAGGTGGTCTCGAAGTGGACCGGCATCCCGGTGTCGCGCCTGATGGAGGGCGAGGTCGAGAAGCTG
CTCGGGATGGAGCAGCGCCTGCACGAGCGGGTGGTCGGGCAGGAGGAGGCGGTGAGCGCCGTCTCCGCGGCGGTGCGCCG
GGCCCGCTCCGGGCTGCAGGACCCGAACCGTCCCATCGGCTCGTTCATCTTCCTCGGCCCCACCGGCGTGGGGAAGACCG
AGACCGCCCGCGCGCTCGCGCAGTTCCTGTTCGACGACGAGCGGGCCATGGTCCGGCTCGACATGTCCGAGTACATGGAG
AAGCACACCGTCTCGCGGCTCATCGGCGCGCCGCCGGGCTACGTCGGCTACGAGGAGGGCGGGCAGCTCACCGAGGCGGT
GCGGCGCCGGCCTTACGCGGTGGTGCTCTTCGACGAGATCGAGAAGGCGCACCACGACGTGTTCAACGTGCTGCTCCAGA
TCCTCGACGACGGCCGGCTCACCGACGGCCAGGGCCGCACGGTGGACTTCCGCAACACGGTCATCATCATGACCTCCAAC
ATCGGCTCGGCCGACATCCAGCGCCTCGCCGGCCGCCCCGGGGCGGACATGCAGCAGATCCGCGAGGCGGCGCTCGAGCA
CCTGCGCGGCGAGTTCCGCCCGGAGTTCCTGAACCGGGTGGACGAGATCGTGGTGTTCCGGCCGCTCGGCCGCGAGGACG
TGGGGCGGATCGTGGAGATCCAGCTCGGCCGGCTGCGCAAGCTCATCGAGGAGCGCCACGTCAGCCTCGAGCTCACCGAG
GCGGCGCGCGAGGCCATCGCCGACGCCGGGTACGATCCGGTCTACGGCGCGCGCCCGCTGAAGCGCGCCATCCAGCGGAT
GGTGCAGGACCCGCTCGCGACGCGCCTGCTCCAGGGCGAGTTCAAGGCCGGCGACCACGTGGTGGTGGACGAGGGCAAGG
ACGGCAACATCGCGTTCCGCAAGGGCGAGCGGCCGGAGGTCACCGTCCACTGA

Protein sequence :
MRMEKLTVKAQEVLAAAQGEARRRDHQAVDVEHLVLALLAQEEGIARPVLEKIGADPRLVASRVEDELRSLPKVSGAEPY
PANRLLKLFDRAEDEARKLKDEYVSTEHLLLAAAEDKGGAGEALRASGATPERVRQAVQEVRGGARVTSPEAESQYRALE
KYAKDLTDLARKGKLDPVIGRDDEIRRVVQILSRRTKNNPVLVGDPGVGKTAIVEGLARRIVDGDVPEGLKNKRLLALDL
GALLAGAKFRGEFEERLKAVLKEVTGSEGQIILFIDEMHTIVGAGAAEGAMDAGNMLKPALARGELHAVGATTVNEYRKH
IEKDPALERRFQPVFVGEPSLTDTISILRGLKDRYELHHKVRIQDAALVEAARLSSRYITDRFLPDKAIDLVDEAASRLR
IEIDSMPTEVDEVRRRIGQLEIERQGLRKEQDEASRARLAAVEKELAARNEEFTALKGRWDAEKAVIQELSQARQELEAL
KVEQAAAERQADFQKAAEIKFGRLPELTRRVKAAEEKLAEAQTRGAMLKEEVTPEEIGEVVSKWTGIPVSRLMEGEVEKL
LGMEQRLHERVVGQEEAVSAVSAAVRRARSGLQDPNRPIGSFIFLGPTGVGKTETARALAQFLFDDERAMVRLDMSEYME
KHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYAVVLFDEIEKAHHDVFNVLLQILDDGRLTDGQGRTVDFRNTVIIMTSN
IGSADIQRLAGRPGADMQQIREAALEHLRGEFRPEFLNRVDEIVVFRPLGREDVGRIVEIQLGRLRKLIEERHVSLELTE
AAREAIADAGYDPVYGARPLKRAIQRMVQDPLATRLLQGEFKAGDHVVVDEGKDGNIAFRKGERPEVTVH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-103 45
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-97 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-97 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A2cp1_0414 YP_002490837.1 ATP-dependent chaperone ClpB VFG2076 Protein 3e-121 45
A2cp1_0414 YP_002490837.1 ATP-dependent chaperone ClpB VFG2084 Protein 1e-100 43