Gene Information

Name : A2cp1_3847 (A2cp1_3847)
Accession : YP_002494237.1
Strain : Anaeromyxobacter dehalogenans 2CP-1
Genome accession: NC_011891
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 4276404 - 4277576 bp
Length : 1173 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: ank:AnaeK_3764 cystathionine gamma-lyase

DNA sequence : 
ATGGCCGACGCCGAGACGAAGCCCGGGTTCGACACCCTCGCCATCCACGCCGGCCAGGCGCCGGATCCGACCACCGGCGC
GATCATGACGCCGGTGTACCTGTCGTCCACCTACGTGCAGGCCTCGCCCGGCGTGCACAAGGGCTTCGAGTACTCGCGCA
CCCGCAACCCGACGCGCGACGCGCTCCAGGGCTGCCTGGCGGCGCTGGAGGGCGGCCGGCACGCGCTCGCGTTCGCCTCC
GGCCTCGCCGCCACCGACGCGATCCTCCACCTGCTCCAGGCGGGCGACCACGTCCTCGCCTCGGACGACGTGTACGGCGG
CACCTTCCGCATCTTCGACAAGGTGTTCCGCCGCCACGGGCTGGAGTTCTCGCACGTGGACATGAGCGACCCGCGCAACG
TGGAGCGCGGGCTGCGCCCGAACACGCGGCTGGTGTGGATCGAGAGCCCCACCAACCCCATGCTGAAGATCGTGGACCTC
GCCGAGGTGGCGCGGATGGCGCGGGCGCACGGGGCGCGCACGGTGGTGGACAACACCTTCGCCACGCCGTACTTCCAGCG
TCCGCTCGAGCTCGGCATCGACCTCGTCGCCCACTCCACCACCAAGTACCTGAACGGCCACTCCGACGTGATCGGCGGGG
CGCTGGTGACCTCGGACGACGCGCTGCACGAGCGGCTCGCGTTCCTGCAGAACGCGGTGGGCGGGGTGCCCGGGCCGCTC
GACAGCTTCCTGGTGCTGCGCGGGCTGAAGACGCTGCACGTGCGCATGCAGCGCCACGCCGAGAACGCGCTCGCGCTGGC
GCGCTTCCTGGAGGGCCACCCGCAGGTGGAGCGCGTCACCTACCCGGGCCTCGCCTCGCACCCGCAGCACGGGCTCGCGG
CCCGGCAGATGAGGGGCTTCGGCGGCATGCTCACGTTCGTGATCCGCGGCGGCCTGCCGGCGGCGCGCGCCTTCCTCGAG
CACGTGCGGATCTTCGCGTGCGCGGAGTCGCTCGGGGGCGTGGAGAGCCTCATCGAGCACCCGGCCATCATGACCCACGC
GTCGGTGCCGAAGGAGACGCGCGAGGCGCTCGGGATCGCGGACGGCTTCATCCGCGTCTCCGCCGGGATCGAGGCGGTGG
ACGACCTCCGAGCCGACCTCGAGCGCGGCTTCGCCGCCGCGCGCCGCGCGTGA

Protein sequence : 
MADAETKPGFDTLAIHAGQAPDPTTGAIMTPVYLSSTYVQASPGVHKGFEYSRTRNPTRDALQGCLAALEGGRHALAFAS
GLAATDAILHLLQAGDHVLASDDVYGGTFRIFDKVFRRHGLEFSHVDMSDPRNVERGLRPNTRLVWIESPTNPMLKIVDL
AEVARMARAHGARTVVDNTFATPYFQRPLELGIDLVAHSTTKYLNGHSDVIGGALVTSDDALHERLAFLQNAVGGVPGPL
DSFLVLRGLKTLHVRMQRHAENALALARFLEGHPQVERVTYPGLASHPQHGLAARQMRGFGGMLTFVIRGGLPAARAFLE
HVRIFACAESLGGVESLIEHPAIMTHASVPKETREALGIADGFIRVSAGIEAVDDLRADLERGFAAARRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-86 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-87 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-64 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A2cp1_3847 YP_002494237.1 cystathionine gamma-lyase BAC0207 Protein 7e-75 45