Gene Information

Name : A2cp1_3333 (A2cp1_3333)
Accession : YP_002493733.1
Strain : Anaeromyxobacter dehalogenans 2CP-1
Genome accession: NC_011891
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3711751 - 3713031 bp
Length : 1281 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ank:AnaeK_3252 cystathionine gamma-synthase

DNA sequence :
ATGTCCGAAGACGTCCACCTCGACTCCAACGTGCCAGGCAACCCGGCCTACCACTTCACCATCGTCGCGCCCGGCACGCC
GGCACGGGCGGGCTGGGCGGAGCGTGCGCCGCTCGTCCCCGGGGCCGCGCTCGCCACGCAGTGCGTCCACGCGGGCGTGC
AGCCCGACCCCGCCTACGGCGCGGTGATGCCGCCCATCTACCAGTCGTCCACGTTCGCGTTCCGCGACGTGTGCACCAAC
GCCGGCTACGACTACACGCGCAGCGGCAACCCGACGCGCGCCGCGCTCGAGGAGGCCATCGCCACGCTGGAGGGAGGCGC
CGGGGCGACCTGCACCACCACCGGCATGGCCGCGGTGCTGGTGGCGCTCAACCTGCTCCCGCACGGCAGCCACCTGCTCT
GTACCGTGGACTGCTACGGCGGCACGTTCCGGACGCTCGAGCACGCGCGGCAGGCGTACGGGCTGGAGGTCACCTACCTC
GACCTCGCCGACCTCGGCGCGGTCGAGCGCGCGCTGCGGCCGAACACCGGGATGGTCTGGATCGAGACGCCGTCGAACCC
GCTGCTCCGCCTCACCGACATCCGCGCGGTGGCCGAGCTGGCGCACCGGCGCGGCGCGCTCGTGGTGGTGGACAACACGT
TCCTCTCGCCGGCGCTCCAGCGCCCGTTCGAGCACGGCGCCGATCTGGTGGTGCACTCCACCACCAAGTACCTGAACGGC
CACAGCGACGTGGTCGGCGGTGCGGTGGTCGCGCCCCGCGGCCGCACCGCGCTCCTGCAGCGCATCCAGTCGATGAACAA
CCTGCTCGGCACCTCCCAGAGCCCGCACGACGCCTTCCTGGTGCTCCGCGGCCTGAAGACGCTGGCGCTGCGCGTGAAGG
CGCACGAGGCCGGCGCGCAGCGGGTGGCGGAGTTCCTGGCCGGCCACCCGCAGGTGGCGCGGGTTCACTACCCCGGCCTC
CCGTCGCACCCGCAGCACGCGCTCGCGCGCGCGCAGCAGCGCGGCTTCGGCGCCATGCTCAGCTTCGAGCTCCGCGACGG
CCGCCCGGATCGGGTGGACCACGTGCTGCGCACGCTGCGCTGGTTCACGCTGGCGGAGTCGCTGGGCGGCGTCGAGAGCC
TGGTGGCGCACCCGGCCTCGATGACGCACGCGTCGATGACGCCGGAGGCGCGGCAGCGGGCGGGCATCACCGACTCCGTG
ATCCGGCTCTCCATCGGCATCGAGGACCCCGCGGACCTGATCGGCGACCTCGACCGCGCGCTCGCGTCGCTGCCGGCCTG
A

Protein sequence :
MSEDVHLDSNVPGNPAYHFTIVAPGTPARAGWAERAPLVPGAALATQCVHAGVQPDPAYGAVMPPIYQSSTFAFRDVCTN
AGYDYTRSGNPTRAALEEAIATLEGGAGATCTTTGMAAVLVALNLLPHGSHLLCTVDCYGGTFRTLEHARQAYGLEVTYL
DLADLGAVERALRPNTGMVWIETPSNPLLRLTDIRAVAELAHRRGALVVVDNTFLSPALQRPFEHGADLVVHSTTKYLNG
HSDVVGGAVVAPRGRTALLQRIQSMNNLLGTSQSPHDAFLVLRGLKTLALRVKAHEAGAQRVAEFLAGHPQVARVHYPGL
PSHPQHALARAQQRGFGAMLSFELRDGRPDRVDHVLRTLRWFTLAESLGGVESLVAHPASMTHASMTPEARQRAGITDSV
IRLSIGIEDPADLIGDLDRALASLPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-64 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-65 42
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-54 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A2cp1_3333 YP_002493733.1 cystathionine gamma-synthase BAC0207 Protein 4e-62 46