Gene Information

Name : A2cp1_2459 (A2cp1_2459)
Accession : YP_002492863.1
Strain : Anaeromyxobacter dehalogenans 2CP-1
Genome accession: NC_011891
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0294
EC number : 2.5.1.15
Position : 2716177 - 2717028 bp
Length : 852 bp
Strand : -
Note : KEGG: ank:AnaeK_2371 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS

DNA sequence : 
ATGCGGATGCGGATCGGGGCCAGGCTCTTCGACGGGCCTGGCCCCTTCGTCATGGGGGTCGTGAACGCGACCCCGGACTC
GTTCTCGGACGGCGGCCGGTTCCTCGAGCGCGACGCGGCGGTGGCGCACGCGCTGCGGCTCGCGGACGAGGGCGCCGATC
TGGTGGACCTGGGCGGCGAGTCCACCCGGCCCGGCGCGCCGCCGGTGACGGCCGACGAGGAGCTCCGGCGGGTGGTGCCG
GTCGTCGCCGCGCTGCGCGCGCGCGGGTTCACGCTCCCGATCTCGGTGGACACGTGGAAGGCGCGGGTGGCGCGGGAGGC
GCTCGCGGCCGGGGCGGACCTGGTGAACGACGTGACCGGCCTCGCCGACCCGGACATGGGCGGCGTGGTCGCCGGGGCCG
GCGTGCCGATCGTGCTCCAGCACATGCGCGGCACGTTCGCCGACATGGCCACGCGCGCGGTGTATGCGGACGTGGTCGAG
GAGGTCGCCGCCGAGCTGGACGAGGCGCTGGCCCGGGCCGGGGCGGCCGGCATCCCGCGCGATCGCGTGGTGCTCGACCC
CGGCATCGGCTTCGCGAAGGACGCCCGGCAGAGCCTGGAGCTGCTGGCGCGGGTCGGGGAGCTGCGGCGCCTCGGGTGCC
CGCTGCTGGTGGGCCCGTCGCGCAAGAGCTTCATCGGGAAGGTCACCGGCGCGCCCGCGGCGGAGCGCCTGCCCGGCACG
CTCGCGGCGGTGACCGCGTGCGTGCTGGCCGGCGTGGAGCTGGTGCGCGTCCACGACGTCGCGGCCGCCCGGCAGGCAGC
CGACGTCGCGGCCGCGATCCGGGGAGCGGCGCGCGCTCCCGGTCCGCTGTAG

Protein sequence : 
MRMRIGARLFDGPGPFVMGVVNATPDSFSDGGRFLERDAAVAHALRLADEGADLVDLGGESTRPGAPPVTADEELRRVVP
VVAALRARGFTLPISVDTWKARVAREALAAGADLVNDVTGLADPDMGGVVAGAGVPIVLQHMRGTFADMATRAVYADVVE
EVAAELDEALARAGAAGIPRDRVVLDPGIGFAKDARQSLELLARVGELRRLGCPLLVGPSRKSFIGKVTGAPAAERLPGT
LAAVTACVLAGVELVRVHDVAAARQAADVAAAIRGAARAPGPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 2e-15 41
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 1e-15 41
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 1e-15 41
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 2e-15 41
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 1e-15 41
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 1e-15 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A2cp1_2459 YP_002492863.1 dihydropteroate synthase AE000516.2.gene3902. Protein 3e-14 50
A2cp1_2459 YP_002492863.1 dihydropteroate synthase CP002695.1.gene1085. Protein 4e-26 48
A2cp1_2459 YP_002492863.1 dihydropteroate synthase NC_002516.2.881715.p Protein 7e-23 48
A2cp1_2459 YP_002492863.1 dihydropteroate synthase NC_008702.1.4608834. Protein 6e-18 46
A2cp1_2459 YP_002492863.1 dihydropteroate synthase NC_011586.7045137.p0 Protein 8e-21 46
A2cp1_2459 YP_002492863.1 dihydropteroate synthase NC_010400.5986775.p0 Protein 2e-21 46
A2cp1_2459 YP_002492863.1 dihydropteroate synthase NC_010410.6003232.p0 Protein 8e-21 46
A2cp1_2459 YP_002492863.1 dihydropteroate synthase NC_011595.7059722.p0 Protein 8e-21 46
A2cp1_2459 YP_002492863.1 dihydropteroate synthase CP001138.1.gene3456. Protein 3e-22 45
A2cp1_2459 YP_002492863.1 dihydropteroate synthase NC_002695.1.916103.p Protein 3e-22 45
A2cp1_2459 YP_002492863.1 dihydropteroate synthase CP000034.1.gene3358. Protein 3e-22 45
A2cp1_2459 YP_002492863.1 dihydropteroate synthase AM180355.1.gene1650. Protein 3e-24 43
A2cp1_2459 YP_002492863.1 dihydropteroate synthase CP000647.1.gene3624. Protein 2e-23 43
A2cp1_2459 YP_002492863.1 dihydropteroate synthase CP004022.1.gene3451. Protein 8e-24 42
A2cp1_2459 YP_002492863.1 dihydropteroate synthase DQ464881.1.gene2.p01 Protein 4e-15 42