Gene Information

Name : A2cp1_1137 (A2cp1_1137)
Accession : YP_002491548.1
Strain : Anaeromyxobacter dehalogenans 2CP-1
Genome accession: NC_011891
Putative virulence/resistance : Virulence
Product : type IV secretion/conjugal transfer ATPase
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 1268795 - 1271245 bp
Length : 2451 bp
Strand : +
Note : TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family; PFAM: CagE TrbE VirB component of type IV transporter system; KEGG: btr:Btr_2518 TrwK protein

DNA sequence :
ATGGGCCGGGTGAACCTGCTGCAGGCGAGCCGGGGCGAGTTGCCGGCCACCGCCTTCGTTCCGTACTCGCACCACGTCAC
GCCGACGATCGTGGCGACGCGCGGAGGCGAGTACCTCTCCGCGTGGAAGCTCGGCGGGCGCGCGCACGAAGCGGCGTCCG
CCGGCGAGCAGGCGGAGTGGGTGGCGGACCTGAACAACGCCTGGCGCGGCCTCGCCGAGGCCGGCGTGGCGTTCTGGTCC
CACGTCGTCCGGCGCCGCGCGGATGCCTTCCCGCGGAGCGCCTTCGACGGGCACTTCTGCCGGCGGCTCGACGCCGCCTA
TGCGGCGACCCTCGCCGGCGCGCGGTTCATGGTGAACGAGCTGTACCTCACGCCGGTCGTCCGGACGGTGGGCGACGAGG
TCCTGGAGGCGCTCGGCCGCCGCGAGAAGGAGGACGTCCCGGCGAAGCTCCGGCGGCAGCAGGACGGCATCGCGAAGCTC
GACGACCTCAACCGGGCGCTCGGCTCGACGCTCCGGCGCTACGGCGCGGAGCTGCTCCGGACGTACGAGGGCGAGGGAGG
GAAGCTCTTCTCGGCCCCGCTCGAGGCGCTGGGGCAGCTCGTGAACGGCGAGCGCCTACCGATGCCGGTCTGCCGCGACC
GCTTCGGCGACTACCTCGTCGTGAACCGGCCGCTCTTCGGCTGGCACGGCGAGGTCGGCGAGCTCCGGCTCGTGGACCGC
GTCCGACGGTTCGGGATGCTCGAGATCGTCGAGTACGACGGGAAGGGTACTACCCCGGGCGACCTCGATGGACTCCTCCG
GGCCGAGTTCGAGTTCATCCTGACGCAGAGCTTCGCCGCGCTCTCGAAGCACGCCGCGAAGGGATTCCTGGAGCGCCACA
AGCAGCGGCTCCTCGACGCCAAGGACGTCGCGAGGAGCCAAGTCGCCGAGATCGACTTCGCACTCGACCAGCTCATGTCG
GGGTCGTTCGTCGTGGGCGAGCACCACGCGACGCTCCTCGCCTTCGGCGAGAGCGCCGACGAGGTGCGCGATCACTTGGC
CTGGGCCAGGTCCGAGCTCCTCGACCGCGGCATCGTGGCGAAGCCGGTGGACCTCGCGCTCGAGGCGGGGTTCTGGGCGC
AGCTGCCGGGGAACCTCCGCTGGAGGCCCCGGCCGATGGCGATCACCTCGCAGAACTTCCTCTGCTTCTCGCCGTTCCAC
AACTTCATGACCGGCAAGGCGGCCGGGAACCCCTGGGGTCCTGCGGTCACGGTTCTCCGGACCGCGAGCGGGACGCCGCT
CTACTTCAACTTCCACGCGTCGCCAGCCGGCGAGGACTCCGAGGGCGAACGGCTTCTCGGGAACACGCTCATCCTCGGCC
AGTCGAGCGCGGGCAAGACCGTGCTCCTCGGCTTCCTCCTCGCACAGGCCCAGAAGTACCGGCCCACTGTGGTCGCCTTC
GACAAGGACCGGGGCCTCGAGATCGCGATCCGCGCCATGGGCGGCTGCTACCTCCCGCTCAAGAGCGGTGAACCGACCGG
CTGGAACCCGGTTCAGCTCGAGCCAACGAGCGCGAACCTCCTCTTCCTGAAGGGGCTCGTGAGGGCGCTCGTGTCGGCGA
ACGGGAGCGAGGTCACGCACGAGGACGAGGTGTGGATCGATCGCTCGGTCGACACGGTGATGACGCTCATCGACCGGAGG
CATCGCCGGCTGTCGCTCCTCCTCGAGTGTCTGCCCGATCCCCTGAACGAGGACGGCGCGCATCCGAGCGTGGCGGCGCG
TCTCCGACGCTGGTGCGAGGGTGGGCCGTACGGCTGGGTGTTCGACAACGCCGAGGACGTGCTCGATCTCGGAACGAACC
GCGTTTACGGCTTCGACATCACCGAGCTCCTCGACTGCGCCGACGCGCGAGGGCCGATGATGAAGTACCTGCTCCACCGC
ACGGAGGCGATGCTCGACGGCCGCCGCTTCATCTACGTCTTCGACGAGTGGTGGCGCGCGCTCAGCGGCGAGGACTTCGC
CGAGCTCACGAAGAACAAGGGGAAGACGATCCGAAAACAGGACGGGTTCCTCGTCCTGTGCACGCAGGAGCCGGACGACG
CGCTCCAGAGCCCCGTGGGCAAGTCGGTCATCCAGCAGTGCGCGACGCTGCTGCTCCTCCGGAATCCGAACGCCACGCGC
GAGGACTACGTCGAGGGTCTGAAGCTTAGCGAGCCCGAGTACGAGCTCGTGCGGTCCCTTCCGGAGCAGAGCCGCCGGTT
CCTCGTGAAGCAGGGTGGCGGCTCGGCGGTGGCGGAGCTCGATCTGTCGGCCATGCCGGAGGCGCTCGCCGTGCTCTCCG
GCACGCCGGACCGGGCCCGGCTCGTCGAGGCTCTCGCGGCGGAGTGTGGCGAGGCTCCGGAGCAGTGGCTGCCCCGGTTC
TGGGAGCGGCTCGGCGTGCCCGTCCAACCGCTCGAGCAGGAGACGCCATGA

Protein sequence :
MGRVNLLQASRGELPATAFVPYSHHVTPTIVATRGGEYLSAWKLGGRAHEAASAGEQAEWVADLNNAWRGLAEAGVAFWS
HVVRRRADAFPRSAFDGHFCRRLDAAYAATLAGARFMVNELYLTPVVRTVGDEVLEALGRREKEDVPAKLRRQQDGIAKL
DDLNRALGSTLRRYGAELLRTYEGEGGKLFSAPLEALGQLVNGERLPMPVCRDRFGDYLVVNRPLFGWHGEVGELRLVDR
VRRFGMLEIVEYDGKGTTPGDLDGLLRAEFEFILTQSFAALSKHAAKGFLERHKQRLLDAKDVARSQVAEIDFALDQLMS
GSFVVGEHHATLLAFGESADEVRDHLAWARSELLDRGIVAKPVDLALEAGFWAQLPGNLRWRPRPMAITSQNFLCFSPFH
NFMTGKAAGNPWGPAVTVLRTASGTPLYFNFHASPAGEDSEGERLLGNTLILGQSSAGKTVLLGFLLAQAQKYRPTVVAF
DKDRGLEIAIRAMGGCYLPLKSGEPTGWNPVQLEPTSANLLFLKGLVRALVSANGSEVTHEDEVWIDRSVDTVMTLIDRR
HRRLSLLLECLPDPLNEDGAHPSVAARLRRWCEGGPYGWVFDNAEDVLDLGTNRVYGFDITELLDCADARGPMMKYLLHR
TEAMLDGRRFIYVFDEWWRALSGEDFAELTKNKGKTIRKQDGFLVLCTQEPDDALQSPVGKSVIQQCATLLLLRNPNATR
EDYVEGLKLSEPEYELVRSLPEQSRRFLVKQGGGSAVAELDLSAMPEALAVLSGTPDRARLVEALAAECGEAPEQWLPRF
WERLGVPVQPLEQETP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trwK YP_001610476.1 TrwK protein Virulence Not named Protein 0.0 55
trwK CAD42844.1 TrwK protein Not tested trw-PAI Protein 0.0 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A2cp1_1137 YP_002491548.1 type IV secretion/conjugal transfer ATPase VFG2259 Protein 0.0 54
A2cp1_1137 YP_002491548.1 type IV secretion/conjugal transfer ATPase VFG2211 Protein 2e-135 42