Gene Information

Name : Achl_2761 (Achl_2761)
Accession : YP_002488815.1
Strain : Arthrobacter chlorophenolicus A6
Genome accession: NC_011886
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3084947 - 3086110 bp
Length : 1164 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGTCCCTGCAGGAAAACCAAGGTTTCAACACCCGCGCGGTGCACGCGGGCCAGGCCTTCGAGCCCCGCACCGGGGCCGT
AGTCCCGCCGCTGCACTTCAGTTCCACGTATGCGCAGGACGGCATCGGCAACCTTCGCAGCGGCTACGAGTACGGCCGCG
GCGGCAACCCCACCCGCGATGCCCTGCAGGAGCAGCTGGCCGCACTGGAACTGGGAACGCACGCCTACAGCTTCAGCTCG
GGCCTGGCCGCCGAGGATGCGCTGATCCGTGCCCTGACCAGGCCAGGGGACCACATTGTGCTCGGCAACGATGCCTATGG
CGGCACCTACCGGCTGATCAGCCGGGTGCTGGGCGACTGGGGCATCGGCAACACCCCGGTGGACATGGCCAACCTGGACA
CCGTCCGCCGCGCCGTCGCCGCGAACAAGACCCGCTTCGTATGGGTGGAGACGCCCTCCAACCCCCTGATGAAGATCACG
GACATCGCAGCGCTCGCGGACATAGCGCACGACGCCGGGGCCCTCCTCGTGGTGGACAACACCTTCGCGTCTCCCTACCT
GCAGAACCCGCTCGCCCTGGGTGCCGACGTAGTGGTCCACTCCACCACGAAGTACATCGGCGGCCACTCCGATGTGGTGG
GCGGCGCCGTGGTGGTCAAGGACGCGGAGCTGGCGGACAAGATCGGCTTCGTGCAGTTCGCCGTGGGGGCGGTGTCCGGG
CCAATGGACGCGTTCCTCACCACCCGCGGCCTGAAGACCCTGGGCGTGCGGATGGACCGGCACAGCGAGAACGGCCAGGC
CGTGGCCGAATGGCTGCTGGAACGCCCCGAAGTCGAGGCCGTCCTGTACCCGGGGCTGCCGTCCCACCCCGGCCACGAGT
TGGCCAAGAGCCAGATGCGCAGTTTTGGCGGGATGGTCTCGGTGCAGTTCAAGGGCGGCGAGGCGGCGGCCCGGAAGGTG
GCCGAATCCACCTCGGTGTTCACCCTGGCCGAGTCCTTGGGCGGCATCGAATCGCTGATGAACTACCCGTCCGAAATGAC
GCACGCTTCGGTCAAGGGCACCGAGCTCGCCGTGCCGGTGAACCTGCTGCGCCTGTCCTGCGGCATCGAGGACAAAGAGG
ACCTGGTGGCTGACCTGGAGCAGGCTTTCTCCTCGATCCCCTGA

Protein sequence :
MSLQENQGFNTRAVHAGQAFEPRTGAVVPPLHFSSTYAQDGIGNLRSGYEYGRGGNPTRDALQEQLAALELGTHAYSFSS
GLAAEDALIRALTRPGDHIVLGNDAYGGTYRLISRVLGDWGIGNTPVDMANLDTVRRAVAANKTRFVWVETPSNPLMKIT
DIAALADIAHDAGALLVVDNTFASPYLQNPLALGADVVVHSTTKYIGGHSDVVGGAVVVKDAELADKIGFVQFAVGAVSG
PMDAFLTTRGLKTLGVRMDRHSENGQAVAEWLLERPEVEAVLYPGLPSHPGHELAKSQMRSFGGMVSVQFKGGEAAARKV
AESTSVFTLAESLGGIESLMNYPSEMTHASVKGTELAVPVNLLRLSCGIEDKEDLVADLEQAFSSIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-63 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-64 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-41 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Achl_2761 YP_002488815.1 cystathionine gamma-synthase BAC0207 Protein 9e-51 42