Gene Information

Name : thyA (Achl_2730)
Accession : YP_002488784.1
Strain : Arthrobacter chlorophenolicus A6
Genome accession: NC_011886
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3055397 - 3056200 bp
Length : 804 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
GTGAGCATCCCCACGCCTTATGAAGACCTTCTGCGCGACGTCCTGGCCCAGGGCACGCACAAATCCGACCGTACGGGCAC
CGGAACCACCAGCGTTTTCGGCCGCCAGATCCGTTTCGACCTGGCCGAAGGCTTCCCGCTCATCACCACCAAGCGGGTCC
ACTTCAAGTCCGTGGCGGTGGAGCTGTTGTGGTTCCTGCGCGGCGAAACCAACGTGAAGTGGATGCAGGACCAGGGCGTC
ACCATCTGGAACGAATGGGCTGACGAGGACGGCGACCTCGGCCCGGTTTACGGTGTGCAGTGGCGCAGCTGGCCCACCCC
GGACGGCGGCCACATCGACCAGATCGCCGAGCTCGTAGAGAACCTCAAGGCCAACCCGGACTCCCGCCGGCACATCGTCT
CTGCCTGGAACGTCTCCGAGCTCAATGACATGGCACTGCCGCCGTGCCACGCGTTCTTCCAGTTCTATGTTGCCGACGGA
AAGCTCTCCTGCCAGCTGTACCAGCGTTCGGCGGACATGTTCCTGGGCGTCCCGTTCAACATCGCCTCCTACGCCCTGCT
CACGTACATGCTGGCGCAGCAGGTGGGCCTTGAGCCCGGCGAATTTGTCTGGACCGGCGGCGACGTCCACATTTACGAGA
ACCACATGGACCAGGTCCTCAAGCAGCTCGAACGCGAGCCTTACGAGTACCCGCAGCTGAAGATCAACAGGAAACCCGCC
TCGATCTTCGACTACACGCTGGAAGACTTCGAGGTGGTCGGTTACAAGCACCACCCCACCATTAAGGCGCCGATTGCCGT
ATGA

Protein sequence :
MSIPTPYEDLLRDVLAQGTHKSDRTGTGTTSVFGRQIRFDLAEGFPLITTKRVHFKSVAVELLWFLRGETNVKWMQDQGV
TIWNEWADEDGDLGPVYGVQWRSWPTPDGGHIDQIAELVENLKANPDSRRHIVSAWNVSELNDMALPPCHAFFQFYVADG
KLSCQLYQRSADMFLGVPFNIASYALLTYMLAQQVGLEPGEFVWTGGDVHIYENHMDQVLKQLEREPYEYPQLKINRKPA
SIFDYTLEDFEVVGYKHHPTIKAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-94 73
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-55 44