Gene Information

Name : guaA (Achl_2576)
Accession : YP_002488630.1
Strain : Arthrobacter chlorophenolicus A6
Genome accession: NC_011886
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2897541 - 2899130 bp
Length : 1590 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACTACTCCCACTGCATCCCAGACTTCCCAGAAGCCGGTGCTGGTTGTTGACTATGGAGCCCAGTACGCGCAGCTGAT
TGCCCGCCGCGTCAGGGAAGCGAATGTGTATTCGGAAGTGGTTCCGCATACTTACACCACCGAACAGCTCCTCGCCAAGA
ACCCCGCCGCGATCATCCTTTCCGGCGGACCTTCCAGCGTTTATGCCGACGGCGCCCCCAGCGTGGGTGCCGATCTCTTC
GAAGCCGGCATCCCCGTCTTTGGCATCTGCTACGGCTTCCAGGCCATGGCCAACGCACTGGGCGGCAAGGTGGACAAGAC
CGGCCTTCGGGAATACGGCTCCACCCAGACCACCATCCTGGGCGAAGGGCGTTCCGTGCTCGAGGGCATGCCCCAGCACC
AGAACACCTGGATGAGCCACGGCGACTCCGTGCACGCGGCTCCGGAGGGCTTTGAGGTCCTGGCCACCACTGCCGGCGCC
GAGGTTGCAGCCTTCGCCAACGAGGAAAAGTGCCTCTACGGCGTGCAGTGGCACCCCGAGGTCAAGCACTCAGCCTACGG
CCAGCAGGTGCTGGAAAACTTCCTCTTCAAGGGCGCCAAGATCGAGCCCAACTGGACCACGGGGAACATCCTCGAAGAGC
AGGTTGAGCGCATCCGCAACCAGATCGGTGATGCCCGGGTCATCTGCGGCCTCTCCGGCGGCGTCGATTCCGCCGTCGCA
GCAGCCCTCGTGCAGCGCGCCGTGGGCGATCAGCTCACGTGTGTGTTCGTTGACCACGGCCTGCTCCGCGAAGGCGAAGC
GGAGCAGGTTGAACGCGACTTTGTCGCCGCCACCGGCGTCAAGCTTTACATCGCGAACGAGCAGGAGCGCTTCCTCTCCG
CACTGGCCGGAGTGAGCGATCCCGAAACCAAGCGCAAGATCATCGGCCGCGAATTCATCCGCGCCTTCGAAGAAGCCGAA
CTGGCCATCATCGCCGAGGCCGCCGCGCACGGTGAGAAGATCAAGTTCCTGGTCCAGGGCACCCTGTACCCGGACGTCGT
CGAATCCGGCGGCGGCGAAGGTGCAGCAAACATCAAGAGCCACCACAACGTGGGCGGCCTCCCCGAGGACCTGCAGTTTG
AGCTCGTCGAGCCGCTGCGGGCCCTGTTCAAGGATGAGGTCCGTGCCGTGGGCGCCCAGCTGGGACTGCCCCAGGAGATC
GTGGGACGCCAGCCGTTCCCGGGCCCGGGCCTGGGTATCCGGATCGTCGGCGACGTCACGAAGGAGCGCCTGGACCTGCT
GCGCAAGGCCGACGCCATCGCCCGCGCCGAGCTGACCGCCGCCGGCCTGGACAACGAGGTGTGGCAGATGCCCGTCGTAC
TGCTGGCAGATGTCCGCAGCGTCGGCGTCATGGGAGACGGCCGCACCTACGGCCACCCCATCGTCCTGCGCCCGGTCTCT
TCCGAGGACGCCATGACCGCCGACTGGTCACGCCTGCCTTATGACCTCCTGGCCCGGATCTCCAACCGGATCACCAATGA
GGTGGACGGCGTTAACCGCGTGGTGCTGGACGTCACCAGCAAGCCGCCGGGAACCATCGAGTGGGAATAG

Protein sequence :
MTTPTASQTSQKPVLVVDYGAQYAQLIARRVREANVYSEVVPHTYTTEQLLAKNPAAIILSGGPSSVYADGAPSVGADLF
EAGIPVFGICYGFQAMANALGGKVDKTGLREYGSTQTTILGEGRSVLEGMPQHQNTWMSHGDSVHAAPEGFEVLATTAGA
EVAAFANEEKCLYGVQWHPEVKHSAYGQQVLENFLFKGAKIEPNWTTGNILEEQVERIRNQIGDARVICGLSGGVDSAVA
AALVQRAVGDQLTCVFVDHGLLREGEAEQVERDFVAATGVKLYIANEQERFLSALAGVSDPETKRKIIGREFIRAFEEAE
LAIIAEAAAHGEKIKFLVQGTLYPDVVESGGGEGAANIKSHHNVGGLPEDLQFELVEPLRALFKDEVRAVGAQLGLPQEI
VGRQPFPGPGLGIRIVGDVTKERLDLLRKADAIARAELTAAGLDNEVWQMPVVLLADVRSVGVMGDGRTYGHPIVLRPVS
SEDAMTADWSRLPYDLLARISNRITNEVDGVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-164 71
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-126 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-126 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-126 50