Gene Information

Name : Achl_2227 (Achl_2227)
Accession : YP_002488281.1
Strain : Arthrobacter chlorophenolicus A6
Genome accession: NC_011886
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2496367 - 2498184 bp
Length : 1818 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
TTGAATACACCCAATGCAGTGCTGCCCCCTGCCCAAAACCACCCTGCCGGAGCCACGCCTGAAGCACCGGTCACCCAGTC
CCTGAAGTCCCACTCGCTGGCCTACATCGATGATCCGCAGCACGGCATCCGTGTCCCGGTAACGGAGATCGCGCTGGAGC
CCTCGCCCAACGGCCAGCCGAACGCCCCTTTCCGCACGTACCGGACAGCGGGCCCGGGAAGCGACCCCGTCCGGGGCCTC
AGCCCTTTCCGGTCGGGATGGATTGAAGGGCGGGATGACACGGAAGAGTACAGCGGAAGGGCACGGAACCTGCTCGACGA
CGGCCGCTCGGCTGTGCGCCGCGGCGCCGCCTCTGCGGAATGGAAAGGCGGGCGCCCGGTGCCCCGCCGCGCCGTCGACG
GCCGGACAGTCACCCAGATGCACTACGCCCGGAAGGGCGTGGTGACGCCGGAAATGCGGTTCGTGGCGCTGCGGGAAAAC
TGTGATCCGGAACTGGTCCGGAGTGAGGTTGCGGCTGGACGGGCCATTATCCCCGCCAATATCAACCATCCGGAGTCCGA
ACCGATGATCATCGGCAAGGCTTTCCTGGTGAAGATCAACGCCAACATCGGCAACTCCGCCGTCACCAGTTCCATCAGGG
AGGAGGTGGACAAGCTGCAGTGGGCCACCCGGTGGGGTGCCGACACGGTGATGGACCTTTCCACGGGCGACGACATCCAC
ACCACCAGGGAATGGCTCATCCGCAATTCCCCCGTGCCGATCGGCACCGTGCCCATCTACCAGGCCCTGGAAAAGGTCAA
CGGCGAGGCGAACGCACTGACGTGGGAAATCTTCCGCGACACCGTCATAGAACAATGTGAACAGGGCGTGGACTATATGA
CGGTCCACGCCGGCGTCCTGCTCCGCTACGTGCCGCTGACCGCCAACAGGGTCACCGGCATCGTGTCCCGGGGCGGGTCC
ATCATGGCGGGATGGTGCCTGGCGCACCACCAGGAGAACTTCCTGTACACGCATTTCGATGAGCTGTGTGAGATCTTCGC
CAAGTACGATGTCGCGTTCTCGCTGGGTGACGGCCTGCGCCCCGGTGCCACCGCCGATGCCAACGACGCTGCGCAGTTCG
CGGAACTCGACACGCTGGCTGAGCTTACGGACCGCGCCTGGAAACATGACGTGCAGGTCATGGTGGAAGGGCCGGGCCAC
GTCCCGTTTCATCTGGTGCGGGAGAACGTGGAGCGCCAGCAGCAACTGTGCAAGGGCGCGCCGTTCTATACGCTGGGGCC
GCTGGTCACCGATGTGGCCCCAGGCTACGACCACATCACCTCAGCCATCGGCGCCACCGAGATCGCGCGCTACGGCACCG
CCATGCTCTGCTACGTCACACCCAAGGAGCATCTGGGACTGCCCGACAGGGACGATGTGAAGACCGGAGTCATCACCTAC
AAAATCGCCGCGCACGCCGCCGACCTGGCCAAGGGCCACCCCGGGGCGCACGAACGGGACGACGCCCTGTCCAAGGCCAG
GTTCGAGTTCCGCTGGCGGGACCAGTTTGCCCTTTCACTTGACCCCGAGACGGCCGAAGCCTTCCATGATGAAACCCTTC
CGGCCGAGCCCGCCAAGACGGCACACTTCTGCTCCATGTGCGGGCCGAAGTTCTGCTCGATGCGGATCAGCCAGGACATC
CGCAATGAGTACGGATCCGCGGAAGCCCAGGCCGCGATAGCCGAAGCGGCATCCGGGATGCGGGAGAAGAGCCAGGAGTT
CCTGGAATCCGGCGGCAAGGTGTACCTTCCCGAGCTGAAAGTCCCGGCCGGCAGCTAA

Protein sequence :
MNTPNAVLPPAQNHPAGATPEAPVTQSLKSHSLAYIDDPQHGIRVPVTEIALEPSPNGQPNAPFRTYRTAGPGSDPVRGL
SPFRSGWIEGRDDTEEYSGRARNLLDDGRSAVRRGAASAEWKGGRPVPRRAVDGRTVTQMHYARKGVVTPEMRFVALREN
CDPELVRSEVAAGRAIIPANINHPESEPMIIGKAFLVKINANIGNSAVTSSIREEVDKLQWATRWGADTVMDLSTGDDIH
TTREWLIRNSPVPIGTVPIYQALEKVNGEANALTWEIFRDTVIEQCEQGVDYMTVHAGVLLRYVPLTANRVTGIVSRGGS
IMAGWCLAHHQENFLYTHFDELCEIFAKYDVAFSLGDGLRPGATADANDAAQFAELDTLAELTDRAWKHDVQVMVEGPGH
VPFHLVRENVERQQQLCKGAPFYTLGPLVTDVAPGYDHITSAIGATEIARYGTAMLCYVTPKEHLGLPDRDDVKTGVITY
KIAAHAADLAKGHPGAHERDDALSKARFEFRWRDQFALSLDPETAEAFHDETLPAEPAKTAHFCSMCGPKFCSMRISQDI
RNEYGSAEAQAAIAEAASGMREKSQEFLESGGKVYLPELKVPAGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 9e-177 61
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 9e-177 61
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-168 61