Gene Information

Name : guaA (Cyan7425_0294)
Accession : YP_002481049.1
Strain : Cyanothece sp. PCC 7425
Genome accession: NC_011884
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 95460 - 97073 bp
Length : 1614 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGCTTTCCTCTACTTCTGAAATCCCTGCTGCTGCTGATCCGGCGAGCCAAGCTGTTAATCGCCCAATGATAGCTATTCT
CGATTTTGGTTCCCAGTATTCCGAACTGATCGCCCGTCGTATTCGGGAAACCCAGGTTTATTCTGAAGTGTTATCCTACC
GCACCACCGCGGCCCAACTGCAAACCCTGAATCTAAAGGGCATTATTCTTTCTGGTGGCCCCAGCTCCGTTTATGACGCT
AAAGCTCCCCTGTGTGACCCAGAGATCTGGAATTTAGGTATTCCTGTGCTGGGAGTTTGCTATGGCATGCAGTTGATGGT
GCAACAGTTGGGTGGAGAGGTAGAGCGATCGGCCCTGGGAGAATATGGCAAAGCCTCCCTGCTGATTGACGACCCCACAG
ATTTGCTGACAAATGTGGAAAACGAAACCACAATGTGGATGAGCCACGGCGATTCCGTCTCCCAATTGCCTGCTGGTTTT
AAAACCCTTGCCCATACGGACAATACCCCCTGTGCGGCGATCGCGGACCACAAGCGCAAATTGTATGGGGTGCAATTTCA
TCCAGAGGTCGTCCATTCCCTGGGTGGCCAGGCTTTAATTCGCAATTTTGTTTATCACATTTGCCAGTGTGAGCCCACCT
GGACTACAGAACTGTTCGTTGAAGAAGCGATCCGGGAAATTCGGGCCAAAGTTGGGGATAAACGGGTGTTGCTGGCCCTT
TCTGGTGGGGTGGATTCCTCCACGCTGGCCTTTTTGCTCTACCGGGCGATCGGTAACCAGCTCACCTGTATGTTTATCGA
TCAGGGCTTCATGCGCAAAAATGAACCGGAGCGGCTGGTGAAACTTTTTCGAGAGCAGTTTCATATTCCGGTGGAGTACG
TTAATGCCAGTGAGCGCTTCCTGGAGCGGTTGGAAGGGGTGACGGACCCAGAGGAAAAACGTAAGCGGATTGGGCACGAA
TTTATTCAGGTATTTGAAGAAGAATCCCGTCGTCTCGGTCCCTTTGACTACTTGGCGCAAGGAACCCTTTACCCGGATGT
GATCGAATCTGCTGATACGAACGTCGATCCAGAAACGGGGGAACGGGTGGCCGTCAAAATCAAAAGCCATCACAATGTCG
GCGGTCTACCCAAGGATCTGCGCTTCAAGCTGGTTGAACCCCTGCGCAAGTTGTTCAAAGATGAAGTCCGCAAGGTAGGG
CGATCGCTGGGCTTACCGGAAGAAATTGTGCAACGGCATCCCTTTCCCGGTCCCGGTCTGGCGATTCGGATTCTGGGTGA
CATTACCCCGGAACGGCTCCATATTCTGCGGGAAGCTGACTTTATTGTGCGTCAGGAAATTAATCGCTCCGGTCTCTATC
AGGAATTCTGGCAGGCCTTTGCGGTGTTGTTACCCATTCGCAGTGTGGGGGTGATGGGGGATCATCGCACCTATGCCTAC
CCGATCGTCCTACGGCTGGTCTCTAGTGAGGATGGCATGACCGCAGATTGGTCCCGGGCTCCCTATGAGTTGCTGGAGAA
AATTTCCAATCGGATTGTCAATGAAGTTCCTGGGGTGAACCGGGTTGTCTACGACATTACCTCCAAACCCCCTGGCACCA
TCGAGTGGGAGTAA

Protein sequence :
MLSSTSEIPAAADPASQAVNRPMIAILDFGSQYSELIARRIRETQVYSEVLSYRTTAAQLQTLNLKGIILSGGPSSVYDA
KAPLCDPEIWNLGIPVLGVCYGMQLMVQQLGGEVERSALGEYGKASLLIDDPTDLLTNVENETTMWMSHGDSVSQLPAGF
KTLAHTDNTPCAAIADHKRKLYGVQFHPEVVHSLGGQALIRNFVYHICQCEPTWTTELFVEEAIREIRAKVGDKRVLLAL
SGGVDSSTLAFLLYRAIGNQLTCMFIDQGFMRKNEPERLVKLFREQFHIPVEYVNASERFLERLEGVTDPEEKRKRIGHE
FIQVFEEESRRLGPFDYLAQGTLYPDVIESADTNVDPETGERVAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVRKVG
RSLGLPEEIVQRHPFPGPGLAIRILGDITPERLHILREADFIVRQEINRSGLYQEFWQAFAVLLPIRSVGVMGDHRTYAY
PIVLRLVSSEDGMTADWSRAPYELLEKISNRIVNEVPGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-140 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-140 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-140 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-127 53