Gene Information

Name : Cyan7425_3142 (Cyan7425_3142)
Accession : YP_002483831.1
Strain : Cyanothece sp. PCC 7425
Genome accession: NC_011884
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 3114437 - 3117598 bp
Length : 3162 bp
Strand : -
Note : KEGG: ana:alr4604 type I site-specific deoxyribonuclease chain R; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases

DNA sequence :
ATGAGCAAGTTCACCACTGAAGACCAGATCGAAGCCTATAACCTCGAACTGCTTGATGCCCTTGGTTATAGCTACAAACA
CGGCTCTACGATCGAACCTGAAGGAGCTGCACCCGAACGGCAAAGCTTTGGTGATGTGCTGCTCAAAGACCGGCTGAATG
AGGTCATTGGGCGGATCAATTCCCACATTCCCCCTGAGATTCGCCAGCAAGCCCAGCGGGAACTGCAAAACATCGCCAGT
CCTGACCTGATCAGCAACAACGAAGCCTTCCACCGCTACCTCACGGAGGGTATCACGGTTGAATACACCAAGAATGGCGA
AATCAAAGGTGAGCAACTCTGGCTGATTGACTGGGACAATCCCGACAATAACGAATTTCTCGCCGTCAACCAGTTCACCG
TCATTGAAGATAACCACAATCGCCGCCCCGATATCATCCTCTTTATTAACGGGCTGCCCCTGGTAGTGATTGAACTCAAA
AATGCCGCTGATGCCAAAGCTAACCTGCAAGCTGCCCATAACCAATTGCAAACCTACAAACGCGAGATTCCCAGCCTCTT
TACCTACAACGCCCTGCTGGTGATCTCCGATGGCATCTCTGCCCGTGCCGGTTCCCTCTCTGCGCCCTACAGCCGCTTCA
GCCAGTGGAAACGCAAACTCCCCAACGGCGAGATTGATAATAACCCCGACACCAACGAACTGGAAATTCTCACCCAGGGG
ATGCTCAATAAAGCCACCCTGCTTGACCTGATCCGACACTTCACCGTTTTTGAAAAGGTCAAGATTGTAGACCCCAACAC
CGAAGTCGTCACCCTGCAAACGATTAAGAAGCTAGCCGCCTATCACCAGTATTACGCCGTCAATTTAGCGGTTGAGAGTG
TCATCGCTGCCACCCGATCCAACTATCGCGGCGGGGTCGTGTGGCACACCCAGGGCAGCGGTAAGTCCCTCTCAATGGTG
TTTCTCAGCGGTAAGCTGGTGCTGGCACTGGATAACCCCACGATTGTTGTCCTCACCGATCGCAACGACCTGGACGATCA
ACTCTTCGATACCTTTGCCGGGTGCCGCCAACTGCTCCGCCAAGATCCCCAACAAGCGGATAACCGGGATGCGGTGCGGG
AACTGCTCAACGTCGCCTCCGGTGGCATCATCTTTACCACCGTGCAAAAGTTTGCCCCGGTCGAAGGGGAAACCCTGTAT
CCCAAGATTAGCGATCGCACCAACATCGTTGTCCTGGCTGATGAAGCTCACCGCAGCCAATACGGATTCAAAGCCAAACA
GGTCAACATCAAAGACGAGCAAGGCAATGTAGTTGGAAAACAGACCCGCTATGGTTTTGCCAAATACATCCGCGATGCCC
TGCCCAAGGCCACCTTCGTTGGTTTCACCGGCACCCCCGTCGAACAGACCGACAAAAACACCCCCCAGGTTTTTGGCAGC
TATATCGACGTTTACGACATTGCCCAGGCAGTCGAAGATGGAGCAACCGTCCCGATTTACTACGAAAGCCGCTTGGTCAA
AGTAGACCTGGACGAACATGGGCGGGAATTGCTGGACGAACTCGACGAAGACCTCAGCTTTGAAGACCTGGGTAGTACTC
AGCAAGCCAAGGCACGGCAAACCCAACTAGAAGCGATCGTCGGCTCCACCCAACGCCTGGAAACGATCGCCCAGGACATC
ATCACCCACTTTGAGAAACGCCAAACCGCCAATCGGGGTAAGGGCATGATCGTTACCCTCAGCCGCCAGATTGCCGCCAA
CCTCTACGACAACATCATCAAACTTCGTCCTGGTTGGCATAGCGACGACCTGAACAGCGGGAAGATCAAAGTCGTCATGA
CTGCCAGTGCCTCCGATGCAGGTAACCTCGTTGCACACCACACCAGCAAGAAGGATCGTCAAGTCCTGGCGCAACGCCTC
AAAGACCCCGACAATGACCTGGAACTCGTCATCGTCTGCGATATGTGGCTCACCGGGTTTGATGCCCCCTGCCTCCACAC
AATGTACATCGACAAGCCCATGAAGGGGCATAACCTGATGCAGGCGATCGCCCGGATCAACCGTGTCTACTTCGAGAAGC
AGGGTGGCTTGATTGTGGATTACTTAGGTGTGGCCCAAGAACTCAAAAATGCCCTCTCCTTCTACTCCCAGAGCGGCGGT
AAAGGCGACCTGACCGTCGATCAAGACGTAGCGATCGGGTTACTGCTGCGAACTCTGGAAGTCGTCGAAGGCATCATGGC
GGAATTCAACTATCAGCCCTACTTCACTGCAAGCACTGGGGATAAACTCAATATTCTCAAATCCGCTACCAACTATGTGG
CTGATCCACAAATCAAAGACCGATTCCTTGATGCGGTGACGGCCCTCTCGAAAAGCTACGCCCTCATCGCCCATCACCCA
GAAGCGATCGCCCAAGCTGAGAAAATTTCCTTCTTCCAGGCGATTCAAGCCAGCCTCCGTAAACTTGAACCCAGTGACGG
CAGCCTCAGCAATGCTGACATCGAAACCGCCATTCGTCAGGTGGTCGATCAAGCTCTTGTCTCCGATACCGTCATCAACA
TCTTTGACGAAGCAGGCATCAAAAGCCCGGATGTCTCGGTGATCTCCGACGAATTCCTGGCAGATGTCGAGGGGATGGAG
CATAAAAACCTGGCGGTGGAACTACTCAAACGCCTGCTCCGGGATGAAGTCAAAGCCCAGCGTCGCACTAACCTCGTCCG
CAGCCGCCAACTTGCCGAAATGTTGGAAGAATCCCTCCGACGCTATCAAAATCAGGTGATCAGCGTGACGGAAGTGATCC
AGGAGCTGATCAGCCTCTCCAAAGATGTCCAGGCTGCGAAACAACGGGGTGAAGAGTTGGGGCTAGAACCCTACGAACTC
GCTTTTTACGATGCCCTGTCCCAAAATCAGAGTGCCAGAGAGGTGATGGGTCAGGACAAATTACGGGAGCTAGCGATCAC
CCTGGTGGTCAGAATCCGCAAGAATGCCACCATTGACTGGAATCTCAAAGAAAGTGTCCGCGCCAGAATGAAGGTCATGG
TCAAACGCCTACTCCGAGAATATGGCTACCCACCTGACATGCAGGCCCTCGCGATCGAGCTAGTGCTGGAGCAAGCTAAG
GTGTTCACGGAATTTGAAGTTGAAACGAATTGCTCCAACTAA

Protein sequence :
MSKFTTEDQIEAYNLELLDALGYSYKHGSTIEPEGAAPERQSFGDVLLKDRLNEVIGRINSHIPPEIRQQAQRELQNIAS
PDLISNNEAFHRYLTEGITVEYTKNGEIKGEQLWLIDWDNPDNNEFLAVNQFTVIEDNHNRRPDIILFINGLPLVVIELK
NAADAKANLQAAHNQLQTYKREIPSLFTYNALLVISDGISARAGSLSAPYSRFSQWKRKLPNGEIDNNPDTNELEILTQG
MLNKATLLDLIRHFTVFEKVKIVDPNTEVVTLQTIKKLAAYHQYYAVNLAVESVIAATRSNYRGGVVWHTQGSGKSLSMV
FLSGKLVLALDNPTIVVLTDRNDLDDQLFDTFAGCRQLLRQDPQQADNRDAVRELLNVASGGIIFTTVQKFAPVEGETLY
PKISDRTNIVVLADEAHRSQYGFKAKQVNIKDEQGNVVGKQTRYGFAKYIRDALPKATFVGFTGTPVEQTDKNTPQVFGS
YIDVYDIAQAVEDGATVPIYYESRLVKVDLDEHGRELLDELDEDLSFEDLGSTQQAKARQTQLEAIVGSTQRLETIAQDI
ITHFEKRQTANRGKGMIVTLSRQIAANLYDNIIKLRPGWHSDDLNSGKIKVVMTASASDAGNLVAHHTSKKDRQVLAQRL
KDPDNDLELVIVCDMWLTGFDAPCLHTMYIDKPMKGHNLMQAIARINRVYFEKQGGLIVDYLGVAQELKNALSFYSQSGG
KGDLTVDQDVAIGLLLRTLEVVEGIMAEFNYQPYFTASTGDKLNILKSATNYVADPQIKDRFLDAVTALSKSYALIAHHP
EAIAQAEKISFFQAIQASLRKLEPSDGSLSNADIETAIRQVVDQALVSDTVINIFDEAGIKSPDVSVISDEFLADVEGME
HKNLAVELLKRLLRDEVKAQRRTNLVRSRQLAEMLEESLRRYQNQVISVTEVIQELISLSKDVQAAKQRGEELGLEPYEL
AFYDALSQNQSAREVMGQDKLRELAITLVVRIRKNATIDWNLKESVRARMKVMVKRLLREYGYPPDMQALAIELVLEQAK
VFTEFEVETNCSN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 48
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 48
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 47
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 45