Gene Information

Name : lysS (Cyan7425_0384)
Accession : YP_002481137.1
Strain : Cyanothece sp. PCC 7425
Genome accession: NC_011884
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 181362 - 182891 bp
Length : 1530 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGAGCAAGCCATCCGATTCTGCCCCCGCCCAACCTTCCTCAACCCTGGAGGACATTCGCGCTACCCGTCTGGATAAGGT
CGATAAACTAAAGCAAGCGGGTTGTAATCCCTATGCCTATCGCTGGGAAGTAAGCCACCACGCCGCTGAACTCCAACGTC
AGTTTGCCGATCTCCCCAGTGGTGCAGAGGTGGAGTTGGAGGTGGGGCTAGCCGGCCGGATTATGGCCCGTCGCTTTATG
GGTAAGCTGGCCTTTGCCACCCTGCAGGATGAAACGGGCACAATTCAGCTTTATCTGGAAAAACAACGCCTGGCTGACCA
CATGGATGCCGAGGCCTTTAAGCGCCTGGATAAACTGATGGACACCGGCGATATTGTTGGGGTGCGGGGAACAGTGAAGC
GCACAGAGAAAGGGGAACTGTCGATCGCCGTGAGCGAGTATGCCATTCTGACCAAATCCTTGCTGCCCCTCCCGGACAAA
TGGCACGGTTTAACGGATGTGGAAAAACGCTATCGGCAACGGTATGTCGATCTAATTGTTAACCCGGAGGTGCGGGAAAC
GTTTCGACGCCGGGCCCTGATCACGGCTGCGATTCGTCGCTATCTCGATCAGCAGGATTTTATTGAAATTGAAACGCCGG
TATTGCAGTTAGAGGCTGGAGGTGCAGAAGCCCGTCCCTTTATCACCTACCACAACACCTTAGAGATGCAGATGTATCTG
CGAATTGCCACAGAGTTGCACCTGAAACGGTTGATTGTTGGCGGTTTTGAAAAGGTATTTGAACTGGGGCGCGTATTTCG
GAATGAAGGGATTTCCACCCGCCATAACCCAGAATTCACAACGATCGAAATTTACCAAGCCTATGCTGATTATCAGGACA
TGATGGCCTTGACCGAAAATTTGATCGTAACGGCAGCAGAAACGGTATTGGGCACGCTCAAAATTGACTATCAGGGAACA
GAAATTGACTTAACTCCCCCCTGGCAGCGGATTACGATGTGGGAGGTGGTGCAGCAAAAAACCGGCCTGGATTTCAGCCA
GTTTACGACCCTTGATGAAGCTAAAGCAGCAGCAGATCAGGCAGGAATTGTCGATCTGGAAAAGTGTGATTCGATCGGTA
AAGTTTTGAACGAAGCCTTTGAACAAAAGGTCGAAGCCACTCTGATGCAACCCACCTTTGTGCTGGACTATCCGGTGGAA
ATTTCGCCCCTAGCCAAACCCCATCGCAGTCAACCGGGCTTAGTGGAGCGGTTTGAACTGTTTATTGTCGGACGGGAAAC
AGCCAATAGTTTTTCTGAGTTAACTGATCCGATCGATCAACGTCAGCGCTTAGAACTGCAAGCCGAACGCAAAGCCGCGG
GAGATCTGGAAGCCCACAGTGTGGATGAAGACTTTCTCACTGCCCTGGAACACGGAATGCCCCCCACGGGAGGATTGGGA
ATTGGCATCGATCGTCTGGTGATGCTGTTAACCAACGCCGCCAGTATTCGGGATGTGATTGCCTTCCCTGTGCTCAAAGC
TGAGAAGTAA

Protein sequence :
MSKPSDSAPAQPSSTLEDIRATRLDKVDKLKQAGCNPYAYRWEVSHHAAELQRQFADLPSGAEVELEVGLAGRIMARRFM
GKLAFATLQDETGTIQLYLEKQRLADHMDAEAFKRLDKLMDTGDIVGVRGTVKRTEKGELSIAVSEYAILTKSLLPLPDK
WHGLTDVEKRYRQRYVDLIVNPEVRETFRRRALITAAIRRYLDQQDFIEIETPVLQLEAGGAEARPFITYHNTLEMQMYL
RIATELHLKRLIVGGFEKVFELGRVFRNEGISTRHNPEFTTIEIYQAYADYQDMMALTENLIVTAAETVLGTLKIDYQGT
EIDLTPPWQRITMWEVVQQKTGLDFSQFTTLDEAKAAADQAGIVDLEKCDSIGKVLNEAFEQKVEATLMQPTFVLDYPVE
ISPLAKPHRSQPGLVERFELFIVGRETANSFSELTDPIDQRQRLELQAERKAAGDLEAHSVDEDFLTALEHGMPPTGGLG
IGIDRLVMLLTNAASIRDVIAFPVLKAEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-103 49
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 4e-80 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002481137.1 lysyl-tRNA synthetase VFG1668 Protein 1e-103 49