Gene Information

Name : guaA (Ddes_1806)
Accession : YP_002480381.1
Strain : Desulfovibrio desulfuricans ATCC 27774
Genome accession: NC_011883
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2180668 - 2182203 bp
Length : 1536 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCCCAGCAAGGTCATTATAATAGACTACGGCTCACAGGTTACCCAGCTTATCGCACGCCGTGTGCGTGAGGCCGGGGT
ATACTCCGAAATTCATTCCTGCGTGACCACCGCCCAGCAGGTGGCCGCCATGAAGCCCCAGGCCATCATCCTTTCCGGCG
GCCCCGCCAGCGTGGGCGAAGCCGACGCACCGGCGCTGGACCCCGGTTTTCTTGAACTGGGTGTGCCCGTGCTCGGCATC
TGCTATGGCATGCAGCTTCTGGCCCGCGAGATGGGCGGGCAGCTGGCCCAGTCTCTCACGCGCGAATACGGCCCGGCCGA
CCTCAATTTCACCGCACCCTGCGCCCTGTGGGAAGGTATCACCGCACCCACCCGCGTATGGATGAGCCATGGCGACAAGG
TGATGGCCCCGCCGCCCGGCTTTACGGTTACTGGCAGCACCAGCACCCTTGAAGTGGCCGCCATGGCCGATGAGACCCGC
AAAATCTACGCCGTGCAGTTCCATCCCGAAGTGCACCACAGCGTGGACGGCGAGCGCATGCTGCACAACTTCCTGTTCAA
GGTCACGGGCATCAAGCCCGACTGGACCATGTCCTCCTTTGTGGAGCGCGTAGTCAAGGAAATGGCCGAGCAGGTGGGCG
ACAAGCACGTGGTCTGCGCCCTTTCGGGCGGTATCGACTCCACAGTGGTGGCCGTGCTGCTGCACAGGGCCATAGGCAAG
CGCCTGCACTGCATCTTTGTGGACAACGGCCTGCTGCGTCTTGGCGAAGGTGATGAGGTGGTCAGCTACCTGCGCGAGCA
TTTTGACCTCAACCTCAACTTCGTGCAGGCGCAGGAGCGCTTTCTTTCCAAGCTCAAAGGCGTGGAAGACCCCGAAAAGA
AACGCAAAATCATCGGCCACACCTTTATTGAAATTTTTGATGAAGAAGCCAACAAGCTGGATCAGGTGGACTTTCTGGCT
CAGGGAACCCTGTATCCCGACGTCATTGAATCCATTTCCCACAAGGGACCCAGCGCCGTCATCAAGAGTCACCACAATGT
GGGCGGCCTGCCCGACACAATGAAGCTCAAGCTTATTGAACCCCTGCGTGAACTCTTCAAGGACGAAGTGCGCAAAGTGG
CGGCCGAACTCGGCATGCCCGACTCCATCGTGTGGCGGCATCCCTTCCCTGGTCCCGGCCTTGCCATCCGTGTGCTTGGC
GAAGTGAGCGAAGAACGCCTCAACATCCTGCGCCAGGCCGACAGGATCGTGCAGCAGGAACTGCGCGAATCCGGCTGGTA
TCGTAAGGTCTGGCAGGGCTTTGCCGTGCTGCTACCCCTCAAGACCGTGGGCGTTATGGGCGACGGGCGCACCTATGAAC
ATGTGGTGGCCCTGCGCGTGGTCGACAGCGTTGACGCCATGACAGCAGACTGGGCGCGCCTGCCCGCTGATCTCATCGAG
CGCATGTCGGGCCGCATCATCAATGAAGTCAAGGGCGTCAACCGTGTGGTTTACGATGTGTCCTCCAAACCGCCCAGCAC
CATTGAATGGGAATAG

Protein sequence :
MPSKVIIIDYGSQVTQLIARRVREAGVYSEIHSCVTTAQQVAAMKPQAIILSGGPASVGEADAPALDPGFLELGVPVLGI
CYGMQLLAREMGGQLAQSLTREYGPADLNFTAPCALWEGITAPTRVWMSHGDKVMAPPPGFTVTGSTSTLEVAAMADETR
KIYAVQFHPEVHHSVDGERMLHNFLFKVTGIKPDWTMSSFVERVVKEMAEQVGDKHVVCALSGGIDSTVVAVLLHRAIGK
RLHCIFVDNGLLRLGEGDEVVSYLREHFDLNLNFVQAQERFLSKLKGVEDPEKKRKIIGHTFIEIFDEEANKLDQVDFLA
QGTLYPDVIESISHKGPSAVIKSHHNVGGLPDTMKLKLIEPLRELFKDEVRKVAAELGMPDSIVWRHPFPGPGLAIRVLG
EVSEERLNILRQADRIVQQELRESGWYRKVWQGFAVLLPLKTVGVMGDGRTYEHVVALRVVDSVDAMTADWARLPADLIE
RMSGRIINEVKGVNRVVYDVSSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-142 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-142 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-141 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-125 50